LRMN Publications
Publications 2009
Amero C, Schanda P, Dura MA, Ayala I, Marion D, Franzetti B, Brutscher B and Boisbouvier J
Fast two-dimensional NMR spectroscopy of high molecular weight protein assemblies.
Journal of the American Chemical Society (2009) 131(10): 3448-3449
Ayala I, Sounier R, Use N, Gans P and Boisbouvier J
An efficient protocol for the complete incorporation of methyl-protonated alanine in perdeuterated protein.
Journal of Biomolecular NMR (2009) 43(2): 111-119
Bruschweiler S, Schanda P, Kloiber K, Brutscher B, Kontaxis G, Konrat R and Tollinger M
Direct observation of the dynamic process underlying allosteric signal transmission.
Journal of the American Chemical Society (2009) 131: 3063-3068
Gal M, Kern T, Schanda P, Frydman L and Brutscher B
An improved ultrafast 2D NMR experiment: Towards atom-resolved real-time studies of protein kinetics at multi-Hz rates.
Journal of Biomolecular NMR (2009) 43(1): 1-10
Lescop E and Brutscher B
Highly automated protein backbone resonance assignment within a few hours: the "BATCH" strategy and software package.
Journal of Biomolecular NMR (2009) 44(1): 43-57
McIntosh LP, Kang HS, Okon M, Nelson ML, Graves BJ and Brutscher B
Detection and assignment of phosphoserine and phosphothreonine residues by (13)C- (31)P spin-echo difference NMR spectroscopy.
Journal of Biomolecular NMR (2009) 43(1): 31-37
Ortega-Roldan JL, Jensen MR, Brutscher B, Azuaga AI, Blackledge M and van Nuland NA
Accurate characterization of weak macromolecular interactions by titration of NMR residual dipolar couplings: application to the CD2AP SH3-C:ubiquitin complex.
Nucleic Acids Research (2009) 37(9): e70
Perard J, Rasia R, Medenbach J, Ayala I, Boisbouvier J, Drouet E and Baudin F
Human initiation factor eIF3 subunit b interacts with HCV IRES RNA through its N-terminal RNA recognition motif.
_ FEBS Letters (2009) 583(1): 70-74
Rasia RM, Noirclerc-Savoye M, Bologna NG, Gallet B, Plevin MJ, Blanchard L, Palatnik JF, Brutscher B, Vernet T and Boisbouvier J
Parallel screening and optimization of protein constructs for structural studies.
Protein Science (2009) 18(2): 434-439
Publications 2008
Bersch B, Favier A, Schanda P, van Aelst S, Vallaeys T, Coves J, Mergeay M and Wattiez R
Molecular structure and metal-binding properties of the periplasmic CopK protein expressed in Cupriavidus metallidurans CH34 during copper challenge.
Journal of Molecular Biology (2008) 380(2): 386-403
Gershenzon NI, Skinner TE, Brutscher B, Khaneja N, Nimbalkar M, Luy B and Glaser SJ
Linear phase slope in pulse design: Application to coherence transfer.
Journal of Magnetic Resonance (2008) 192(2): 235-243
Kern T, Hediger S, Muller P, Giustini C, Joris B, Bougault C, Vollmer W and Simorre JP
Toward the characterization of peptidoglycan structure and protein-peptidoglycan interactions by solid-state NMR spectroscopy.
Journal of the American Chemical Society (2008) 130(17): 5618-5619
Kern T, Schanda P and Brutscher B
Sensitivity-enhanced IPAP-SOFAST-HMQC for fast-pulsing 2D NMR with reduced radiofrequency load.
Journal of Magnetic Resonance (2008) 190(2): 333-338
Lescop E, Rasia R and Brutscher B
Hadamard amino-acid-type edited NMR experiment for fast protein resonance assignment.
Journal of the American Chemical Society (2008) 130(15): 5014-5015
Marx JC, Poncin J, Simorre JP, Ramteke PW and Feller G
The noncatalytic triad of alpha-amylases: A novel structural motif involved in conformational stability.
Proteins (2008) 70(2): 320-328
Nodet G, Abergel D and Bodenhausen G
Predicting NMR relaxation rates in anisotropically tumbling proteins through networks of coupled rotators.
Chemphyschem (2008) 9(4): 625-633
Ribeiro EA, Favier A, Gerard FCA, Leyrat C, Brutscher B, Blondel D, Ruigrok RW, Blackledge M and Jamin M
Solution structure of the C-terminal nucleoprotein-RNA binding domain of the vesicular stomatitis virus phosphoprotein.
Journal of Molecular Biology (2008) 382(2): 525-538
Schanda P, Brutscher B, Konrat R and Tollinger M
Folding of the KIX domain: Characterization of the equilibrium analog of a folding intermediate using 15N/13C relaxation dispersion and fast 1H/2H amide exchange NMR spectroscopy.
Journal of Molecular Biology (2008) 380(4): 726-741
Van Melckebeke H, Devany M, Di Primo C, Beaurain F, Toulme JJ, Bryce DL and Boisbouvier J
Liquid-crystal NMR structure of HIV TAR RNA bound to its SELEX RNA aptamer reveals the origins of the high stability of the complex.
Proceedings of the National Academy of Sciences U S A (2008) 105(27): 9210-9215
Publications 2007
Boudet J, Chouquet A, Chahboune A, Giustini C, Joris B, Simorre JP and Bougault CM
1H, 13C and 15N resonance assignments of YajG, an Escherichia coli protein of unknown structure and function.
Biomolecular NMR Assignments (2007) 1: 89-91
Cho MK, Kim HY, Bernado P, Fernandez CO, Blackledge M and Zweckstetter M
Amino acid bulkiness defines the local conformations and dynamics of natively unfolded alpha-synuclein and tau.
Journal of the American Chemical Society (2007) 129(11): 3032-3033
D’Autreaux B, Pecqueur L, Peredo AG, Diederix RE, Caux-Thang C, Tabet L, Bersch B, Forest E and Michaud-Soret I
Reversible redox- and zinc-dependent dimerization of the Escherichia coli Fur protein.
Biochemistry (2007) 46(5): 1329-1342
Bernado P, Mylonas E, Petoukhov MV, Blackledge M and Svergun DI
Structural characterization of flexible proteins using small-angle X-ray scattering.
Journal of the American Chemical Society (2007) 129(17): 5656-5664
Gal M, Schanda P, Brutscher B and Frydman L
UltraSOFAST HMQC NMR and the repetitive acquisition of 2D protein spectra at Hz rates.
Journal of the American Chemical Society (2007) 129(5): 1372-1377
Giraud N, Blackledge M, Bockmann A and Emsley L
The influence of nitrogen-15 proton-driven spin diffusion on the measurement of nitrogen-15 longitudinal relaxation times.
Journal of Magnetic Resonance (2007) 184(1): 51-61
Houben K, Blanchard L, Blackledge M and Marion D
Intrinsic dynamics of the partly unstructured PX domain from the Sendai virus RNA polymerase co-factor P.
Biophysical Journal (2007) 93(8): 2830-2844
Houben K, Marion D, Tarbouriech N, Ruigrok RW and Blanchard L
Interaction of the C-terminal domains of the sendai virus N and P proteins: Comparison of polymerase-nucleocapsid interaction within the paramyxovirus family.
Journal Of Virology (2007) 81(13): 6807-6816
Lescop E and Brutscher B
Hyperdimensional protein NMR spectroscopy in peptide-sequence space.
Journal of the American Chemical Society (2007) 129(39): 11916-11917
Lescop E, Schanda P and Brutscher B
A set of BEST triple-resonance experiments for time-optimized protein resonance assignment.
Journal of Magnetic Resonance (2007) 129(10): 2756-2757
Lescop E, Schanda P, Rasia R and Brutscher B
Automated spectral compression for fast multidimensional NMR and increased time resolution in real-time NMR spectroscopy.
Journal of the American Chemical Society (2007) 129(10): 2756-2757
Manon F, Favier A, Nuñez G, Simorre JP and Cusack S
Solution structure of NOD1 CARD and mutational analysis of its interaction with the CARD of downstream kinase RICK.
Journal of Molecular Biology (2007) 365(1): 160-174
Markwick PR, Bouvignies G and Blackledge M
Exploring multiple timescale motions in protein GB3 using accelerated molecular dynamics and NMR spectroscopy.
Journal of the American Chemical Society (2007) 129(15): 4724-4730
Markwick PR, Doltsinis NL and Schlitter J
Probing irradiation induced DNA damage mechanisms using excited state Car-Parrinello molecular dynamics.
Journal of Chemical Physics (2007) 126(4): 045104
Meier S, Strohmeier M, Blackledge M and Grzesiek S
Direct observation of dipolar couplings and hydrogen bonds across a beta-hairpin in 8 M urea.
Journal of the American Chemical Society (2007) 129(4): 754-755
Mukrasch MD, Markwick P, Biernat J, Bergen M, Bernado P, Griesinger C, Mandelkow E, Zweckstetter M and Blackledge M
Highly populated turn conformations in natively unfolded tau protein identified from residual dipolar couplings and molecular simulation.
Journal of the American Chemical Society (2007) 129(16): 5235-5243
Palatnik JF, Wollmann H, Schommer C, Schwab R, Boisbouvier J, Rodriguez R, Warthmann N, Allen E, Dezulian T, Huson D, Carrington JC and Weigel D
Sequence and expression differences underlie functional specialization of Arabidopsis microRNAs miR159 and miR319.
Developmental Cell (2007) 13(1): 115-125
Pannetier N, Houben K, Blanchard L and Marion D
Optimized 3D-NMR sampling for resonance assignment of partially unfolded proteins.
Journal of Magnetic Resonance (2007) 186(1): 142-149
Quinaud M, Ple S, Job V, Contreras-Martel C, Simorre JP, Attree I and Dessen A
Structure of the heterotrimeric complex that regulates type III secretion needle formation.
Proceedings of the National Academy of Sciences U S A (2007) 104(19): 7803-7808
Rouhier N, Kauffmann B, Tete-Favier F, Palladino P, Gans P, Branlant G, Jacquot JP and Boschi-Muller S
Functional and structural aspects of poplar cytosolic and plastidial type a methionine sulfoxide reductases.
Journal of Biological Chemistry (2007) 282(5): 3367-3378
Schanda P, Lescop E, Falge M, Sounier R, Boisbouvier J and Brutscher B
Sensitivity-optimized experiment for the measurement of residual dipolar couplings between amide protons.
Journal of Biomolecular NMR (2007) 38(1): 47-55
Sein J, Giraud N, Blackledge M and Emsley L
The role of (15)N CSA and CSA/dipole cross-correlation in (15)N relaxation in solid proteins.
Journal of Magnetic Resonance (2007) 168(1): 26-33
Sounier R, Blanchard L, Wu Z and Boisbouvier J
High-accuracy distance measurement between remote methyls in specifically protonated proteins.
Journal of the American Chemical Society (2007) 129(3): 472-473
Tarendeau F, Boudet J, Guilligay D, Mas PJ, Bougault CM, Boulo S, Baudin F, Ruigrok RW, Daigle N, Ellenberg J, Cusack S, Simorre JP and Hart DJ
Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit.
Nature Structural and Molecular Biology (2007) 14(3): 229-233
Publications 2006
Bernado P, Blackledge M and Sancho J
Sequence-specific solvent accessibilities of protein residues in unfolded protein ensembles.
Biophysical Journal (2006) 91(12): 4536-4543
Bouvignies G, Markwick P, Bruschweiler R and Blackledge M
Simultaneous determination of protein backbone structure and dynamics from residual dipolar couplings.
Journal Of The American Chemical Society (2006) 128(47): 15100-15101
Bouvignies G, Meier S, Grzesiek S and Blackledge M
Ultrahigh-resolution backbone structure of perdeuterated protein GB1 using residual dipolar couplings from two alignment media.
Angewandte Chemie International Edition (2006) 45(48): 8166-8169
Dames SA, Aregger R, Vajpai N, Bernado P, Blackledge M and Grzesiek S
Residual dipolar couplings in short peptides reveal systematic conformational preferences of individual amino acids.
Journal of the American Chemical Society (2006) 128(41): 13508-13514
Giraud N, Sein J, Pintacuda G, Bockmann A, Lesage A, Blackledge M and Emsley L
Observation of heteronuclear overhauser effects confirms the N-15-H-1 dipolar relaxation mechanism in a crystalline protein.
Journal of the American Chemical Society (2006) 128(38): 12398-12399
Losonczi J, Kupce E, Gray G, Sandor P and Brutscher B
Aligning ultrafast NMR spectroscopy and cold probe technology to reveal the mysteries of protein dynamics.
American Laboratory (2006) 38(6): 23-+
Marion D
Processing of ND NMR spectra sampled in polar coordinates: a simple Fourier transform instead of a reconstruction.
Journal of Biomolecular NMR (2006) 36(1): 45-54
Pecqueur L, D’Autréaux B, Dupuy J, Nicolet Y, Jacquamet L, Brutscher B, Michaud-Soret I and Bersch B
Structural changes of Escherichia coli ferric uptake regulator during metal-dependent dimerization and activation explored by NMR and x-ray crystallography.
Journal of Biological Chemistry (2006) 281(30): 21286-21295
Reinscheid UM, Farjon J, Radzom M, Haberz P, Zeeck A, Blackledge M and Griesinger C
Effect of the Solvent on the Conformation of a Depsipeptide: NMR-Derived Solution Structure of Hormaomycin in DMSO from Residual Dipolar Couplings in a Novel DMSO-Compatible Alignment Medium.
Chembiochem (2006) 7(2): 287-296
Rouhier N, Gama F, Wingsle G, Gelhaye E, Gans P and Jacquot JP
Engineering functional artificial hybrid proteins between poplar peroxiredoxin II and glutaredoxin or thioredoxin.
Biochemica and Biophysica Research Communications (2006) 341(4): 1300-1308
Schanda P and Brutscher B
Hadamard frequency-encoded SOFAST-HMQC for ultrafast two-dimensional protein NMR.
Journal of Magnetic Resonance (2006) 178(2): 334-339
Schanda P, Forge V and Brutscher B
HET-SOFAST NMR for fast detection of structural compactness and heterogeneity along polypeptide chains.
Magnetic Resonance in Chemistry: MRC (2006) 44(sp): S177-S184
Schanda P, Van Melckebeke H and Brutscher B
Speeding up three-dimensional protein NMR experiments to a few minutes.
Journal of the American Chemical Society (2006) 128(28): 9042-9043
Sendra V, Cannella D, Bersch B, Fieschi F, Menage S, Lascoux D and Coves J
CopH from Cupriavidus metallidurans CH34. A novel periplasmic copper-binding protein.
Biochemistry (2006) 45(17): 5557-5566
Skora L, Cho MK, Kim HY, Fernandez C, Blackledge M and Zweckstetter M
Charge-induced molecular alignment of intrinsically disordered proteins.
Angewandte Chemie International Edition (2006) 45: 7012-7015
Publications 2005
Bernado P, Bertoncini CW, Griesinger C, Zweckstetter M and Blackledge M
Defining long-range order and local disorder in native alpha-synuclein using residual dipolar couplings.
Journal of the American Chemical Society (2005) 127(51): 17968-17969
Bernado P, Blanchard L, Timmins P, Marion D, Ruigrok RW and Blackledge M
A structural model for unfolded proteins from residual dipolar couplings and small-angle x-ray scattering. Proc Natl Acad Sci U S A (2005) 102(47): 17002-17007
Bouvignies G, Bernado P, Meier S, Cho K, Grzesiek S, Bruschweiler R and Blackledge M
Identification of slow correlated motions in proteins using residual dipolar and hydrogen-bond scalar couplings
Proc Natl Acad Sci U S A (2005) 102(39): 13885-13890
Bouvignies G, Bernado P and Blackledge M
Protein backbone dynamics from N-HN dipolar couplings in partially aligned systems: a comparison of motional models in the presence of structural noise
Journal of Magnetic Resonance (2005) 173(2): 328-338
Blackledge M
Recent progress in the study of biomolecular structure and dynamics in solution from residual dipolar couplings
Progress in Nuclear Magnetic Resonance Spectroscopy (2005) 46(1): 23-61
Deprez C, Lloubes R, Gavioli M, Marion D, Guerlesquin F and Blanchard L
Solution Structure of the E.coli TolA C-terminal Domain Reveals Conformational Changes upon Binding to the Phage g3p N-terminal Domain
Journal of Molecular Biology (2005) 346(4): 1047-1057
Friebe P, Boudet J, Simorre JP and Bartenschlager R
Kissing-loop interaction in the 3’ end of the hepatitis C virus genome essential for RNA replication
Journal of Virology (2005) 79(1): 380-392
Giraud N, Blackledge M, Goldman M, Bockmann A, Lesage A, Penin F and Emsley L
Quantitative analysis of backbone dynamics in a crystalline protein from nitrogen-15 spin-lattice relaxation.
Journal of the American Chemical Society (2005) 127(51): 18190-18201
Jaroniec CP, Boisbouvier J, Tworowska I, Nikonowicz EP and Bax A
Accurate measurement of 15N-13C residual dipolar couplings in nucleic acids
J Biomol NMR (2005) 31(3): 231-241
Marion D
Fast acquisition of NMR spectra using Fourier transform of non-equispaced data.
Journal of Biomolecular NMR (2005) 32(2): 141-150
Nálezková M, de Groot A, Graf M, Gans P and Blanchard L
Overexpression and purification of Pyrococcus abyssi phosphopantetheine adenylyltransferase (PPAT) from an optimized synthetic gene for NMR studies
Protein Expression and Purification (2005) 39(2): 296-306
Schanda P and Brutscher B
Hadamard frequency-encoded SOFAST-HMQC for ultrafast two-dimensional protein NMR.
J Magn Reson (2005) 178(2): 334-339
Schanda P, Kupce E and Brutscher B
SOFAST-HMQC Experiments for Recording Two-dimensional Deteronuclear Correlation Spectra of Proteins within a Few Seconds.
Journal of Biomolecular NMR (2005) 33(4): 199-211
Schanda P and Brutscher B
Very fast two-dimensional NMR spectroscopy for real-time investigation of dynamic events in proteins on the time scale of seconds
Journal of the American Chemical Society (2005) 127(22): 8014-8015
Sibille N, Blackledge M, Brutscher B, Coves J and Bersch B
Solution Structure of the Sulfite Reductase Flavodoxin-like Domain from Escherichia coli
Biochemistry (2005) 44(25): 9086-9095
Van Melckebeke H, Pardi A, Boisbouvier J, Simorre JP and Brutscher B
Resolution-Enhanced Base-Type-Edited HCN Experiment for RNA.
Journal of Biomolecular NMR (2005) 32(4): 263-271
Publications 2004
Bernado P and Blackledge M
Anisotropic small amplitude Peptide plane dynamics in proteins from residual dipolar couplings
Journal of the American Chemical Society (2004) 126(15): 4907-20
Bernadó P and Blackledge M
Local dynamic amplitudes on the protein backbone from dipolar couplings: toward the elucidation of slower motions in biomolecules.
Journal of the American Chemical Society (2004) 126(25): 7760 - 1761
Blanchard L, Tarbouriech N, Blackledge M, Timmins P, Burmeister W P, Ruigrok R W H and Marion D
Structure and dynamics of the nucleocapsid-binding domain of the Sendai virus phosphoprotein in solution.
Virology (2004) 319(2): 201-211
Brutscher B
DEPT spectral editing in HCCONH-type experiments. Application to fast protein backbone and side chain assignment
Journal of Magnetic Resonance (2004) 167(2): 178-184
Brutscher B
Combined frequency- and time-domain NMR spectroscopy. Application to fast protein resonance assignment
Journal of Biomolecular NMR (2004) 29(1): 57-64
Duraffourg N, Ollagnier de Choudens S, Fontecave M, Loiseau L, Barras F, Marion D and Blanchard L
Assignment of the 1H, 15N and 13C resonances of SufA from Escherichia coli involved in Fe-S cluster biosynthesis.
Journal of Biomolecular NMR (2004) 30(3): 379-380
Giraud N, Böckmann A, Lesage A, Penin F, Blackledge M and Emsley L
Site-specific backbone dynamics from a crystalline protein by solid-state NMR spectroscopy.
Journal of the American Chemical Society (2004) 126(37): 11422 - 3
Marion D
Measurement of dipole-dipole cross-correlated relaxation in fast rotating CH2D groups.
Journal of Magnetic Resonance (2004) 166(2): 202-214
Prestegard J H, Bougault C M and Kishore A I
Residual dipolar couplings in structure determination of biomolecules
Chemical Reviews (2004) 104(8): 3519-3540
Rossy E, Champier L, Bersch B, Brutscher B, Blackledge M and Coves J
Biophysical characterization of the MerP-like amino-terminal extension of the mercuric reductase from Ralstonia metallidurans CH34.
Journal of Biological Inorganic Chemistry (2004) 9(1): 49-58
Van Melckebeke H, Simorre J-P and Brutscher B
Suppression of artifacts induced by homonuclear decoupling in amino-acid-type edited methyl 1H-13C correlation experiments
Journal of Magnetic Resonance (2004) 170(2): 199-205
Van Melckebeke H, Simorre J-P and Brutscher B
Amino Acid-type edited NMR experiments for methyl-methyl distance measurement in (13)c-labeled proteins
Journal of the American Chemical Society (2004) 126(31): 9584-9591
Vanhaverbeke C, Simorre J P, Sadir S, Gans P and Lortat Jacob H
NMR characterisation of the interaction between the C-terminal domain of Interferon-g and heparin-derived oligosaccharides
Biochemical Journal (2004) 384(1): 93-99
Vreuls C, Filée P, Van Melckebeke H, Aerts T, De Deyn P, Llabres G, Matagne A, Simorre J P, Frère J and Joris B
Guanidine hydrochloride denaturation of the dimeric B. licheniformis BlaI repressor highlights an independent domain unfolding pathway
Biochemical Journal (2004) 384(1): 179-190
Publications 2003
Armengaud J, Fernandez B, Chaumont V, Rollin Genetet F, Finet S, Marchetti C, Myllykallio H, Vidaud C, Pellequer J L, Gribaldo S, Forterre P, Gans P, Yang Y, Sanchez J F, Strub M P, Brutscher B and Aumelas A
Identification, purification, and characterization of an eukaryotic-like phosphopantetheine adenylyltransferase (coenzyme A biosynthetic pathway) in the hyperthermophilic archaeon Pyrococcus abyssi NMR structure of the cathelin-like domain of the protegrin-3 precursor
Journal of Biological Chemistry (2003) 278(33): 31078-87
Bersch B, Rossy E, Coves J and Brutscher B
Optimized set of two-dimensional experiments for fast sequential assignment, secondary structure determination, and backbone fold validation of C-13/N-15-labelled proteins
Journal of Biomolecular Nmr (2003) 27(1): 57-67
Bouvier D, Vanhaverbeke C, Simorre J P, Arlaud G J, Bally I, Forge V, Margolis R L, Gans P and Kleman J P
Unusual Ca2+-calmodulin binding interactions of the microtubule-associated protein F-STOP
Biochemistry (2003) 42(39): 11484-11493
Debonis S, Simorre J P, Crevel I, Lebeau L, Skoufias D A, Blangy A, Ebel C, Gans P, Cross R, Hackney D D, Wade R H and Kozielski F
Interaction of the mitotic inhibitor monastrol with human kinesin Eg5
Biochemistry (2003) 42(2): 338-49.
Duma L, Hediger S, Brutscher B, Bockmann A and Emsley L
Resolution enhancement in multidimensional solid-state NMR spectroscopy of proteins using spin-state selection
Journal of the American Chemical Society (2003) 125(39): 11816-11817
Graciet E, Gans P, Wedel N, Lebreton S, Camadro J M and Gontero B
The small protein CP12: A protein linker for supramolecular complex assembly
Biochemistry (2003) 42(27): 8163-8170
Juy M, Penin F, Favier A, Galinier A, Montserret R, Haser R, Deutscher J and Bockmann A
Dimerization of Crh by Reversible 3D Domain Swapping Induces Structural Adjustments to its Monomeric Homologue Hpr
Journal of Molecular Biology (2003) 332(4): 767-776
Van Melckebeke H, Vreuls C, Gans P, Filée P, Llabres G, Joris B and Simorre J
Solution structural study of BlaI: implications for the repression of genes involved in beta-lactam antibiotic resistance.
Journal of Molecular Biology (2003) 333(4): 711 - 20
Vanbelle C, Brutscher B, Blackledge M, Muhle-Goll C, Remy M H, Masson J M and Marion D
NMR Study of the Interaction between Zn(II) Ligated Bleomycin and Streptoalloteichus hindustanus Bleomycin Resistance Protein
Biochemistry (2003) 42(3): 651-663.
Vella F, Thielens N M, Bersch B, Arlaud G J and Frachet P
A Recombinant Chimeric Epidermal Growth Factor-like Module with High Binding Affinity for Integrins
The Journal Of Biological Chemistry (2003) 278(22): 19834-19843
Wu H W, Blackledge M, Maciejewski M W, Mullen G P and King S M
Relaxation-based structure refinement and backbone molecular dynamics of the dynein motor domain-associated light chain
Biochemistry (2003) 42(1): 57-71
Yang Y, Sanchez J F, Strub M P, Brutscher B and Aumelas A
NMR structure of the cathelin-like domain of the protegrin-3 precursor
Biochemistry (2003) 42(16): 4669-80
Publications 2002
Béraud S, Bersch B, Brutscher B, Gans P, Barras F and Blackledge M
Direct structure determination using residual dipolar couplings: reaction-site conformation of methionine sulfoxide reductase in solution.
Journal of the American Chemical Society (2002) 124(46): 13709 - 15
Brutscher B
Intraresidue HNCA and COHNCA experiments for protein backbone resonance assignment.
Journal of Magnetic Resonance (2002) 156(1): 155-9.
Champier L, Sibille N, Bersch B, Brutscher B, Blackledge M and Coves J
Reactivity, secondary structure, and molecular topology of the Escherichia coli sulfite reductase flavodoxin-like domain
Biochemistry (2002) 41(11): 3770-80
D’autreaux B, Touati D, Bersch B, Latour J M and Michaud Soret I
Direct inhibition by nitric oxide of the transcriptional ferric uptake regulation protein via nitrosylation of the iron
Proceedings of the National Academy of Science U S A (2002) 99(26): 16619-24
Deprez C, Blanchard L, Guerlesquin F, Gavioli M, Simorre JP, Lazdunski C, Marion D and Lloubes R
Macromolecular import into Escherichia coli: the TolA C-terminal domain changes conformation when interacting with the colicin A toxin
Biochemistry (2002) 41(8): 2589-98
Favier A, Brutscher B, Blackledge M, Galinier A, Deutscher J, Penin F and Marion D
Solution Structure and Dynamics of Crh, the Bacillus subtilis Catabolite Repression HPr
Journal of Molecular Biology (2002) 317(1): 131-44
Sibille N, Bersch B, Covès J, Blackledge M and Brutscher B
Side chain orientation from methyl 1H-1H residual dipolar couplings measured in highly deuterated proteins.
Journal of the American Chemical Society (2002) 124(49): 14616 - 25
Publications 2001
Arlaud, G. J., Gaboriaud, C., Thielens, N. M., Rossi, V., Bersch, B., Hernandez, J. F. and Fontecilla Camps, J. C.
Structural biology of C1: dissection of a complex molecular machinery.
Immunological Reviews (2001) 180: 136-145
Beraud S, Chambost JP, Bersch B, Gans P, Barras F and Marion D
Backbone H(N), N, Calpha, C’ and Cbeta assignment of the 25 kDa peptide methionine sulfoxide reductase from Erwinia chrysanthemi
Journal of Biomolecular NMR (2001) 20(1): 97-8
Beraud, S., Chambost, J. P., Bersch, B., Gans, P., Barras, F. and Marion, D.
Letter to the Editor: Backbone H-N, N, C-alpha, C ’ and C-beta assignment of the 25 kDa peptide methionine sulfoxide reductase from Erwinia chrysanthemi.
Journal of Biomolecular Nmr (2001) 20(1): 97-98
Bouchayer E, Stassinopoulou CI, Tzougraki CH, Marion D and Gans P
NMR and CD conformational studies of the C-terminal 16-peptides of Pseudomonas aeruginosa c551 and Hydrogenobacter thermophilus c552 cytochromes
Journal of Peptide Research (2001) 57(1): 39-47
Brutscher B
Accurate measurement of small spin-spin couplings in partially aligned molecules using a novel j-mismatch compensated spin-state-selection filter
Journal of Magnetic Resonance (2001) 151(2): 332-8
Brutscher B, Boisbouvier J, Kupce E, Tisne C, Dardel F, Marion D and Simorre JP
Base-type-selective high-resolution C-13 edited NOESY for sequential assignment of large RNAs
Journal of Biomolecular Nmr (2001) 19(2): 141-151
Dosset, P., Hus, J. C., Marion, D. and Blackledge, M.
A novel interactive tool for rigid-body modeling of multi-domain macromolecules using residual dipolar couplings.
Journal of Biomolecular Nmr (2001) 20(3): 223-231
Didier C, Pouget J, Cadet J, Favier A, Beani J and Richard M
Modulation of exogenous and endogenous levels of thioredoxin in human skin fibroblasts prevents DNA damaging effect of ultraviolet A radiation
Free Radical Biology and Medicine (2001) 30(5): 537-546
Favier A, Blackledge M, Simorre JP, Crouzy S, Dabouis V, Gueiffier A, Marion D and Debouzy JC
Solution structure of 2-(pyrido[1,2-e]purin-4-yl)amino-ethanol intercalated in the DNA duplex d(CGATCG)2
Biochemistry (2001) 40(30): 8717-26
Hus JC, Marion D and Blackledge M
Determination of protein backbone structure using only residual dipolar couplings
Journal of the American Chemical Society (2001) 123(7): 1541-1542
Legrand P, Bibert S, Jaquinod M, Ebel C, Hewat E, Vincent F, Vanbelle C, Concord E, Vernet T and Gulino D
Self-assembly of the Vascular Endothelial Cadherin Ectodomain in a Ca2+- dependent Hexameric Structure
Journal of Biological Chemistry (2001) 276(5): 3581-3588
Marion, D., Tarbouriech, N., Ruigrok, R. W., Burmeister, W. P. and Blanchard, L.
Assignment of the 1H, 15N and 13C resonances of the nucleocapsid- binding domain of the Sendai virus phosphoprotein.
Journal of Biomolecular NMR (2001) 21(1): 75-6.
Penin F, Favier A, Montserret R, Brutscher B, Deutscher J, Marion D and Galinier D
Evidence for a dimerisation state of the Bacillus subtilis catabolite repression HPr-like protein, Crh
Journal of Molecular Microbiology and Biotechnology (2001) 3(3): 429-32
Sibille, N., Coves, J., Marion, D., Brutscher, B. and Bersch, B.
1H, 13C and 15N assignment of the flavodoxin-like domain of the Escherichia coli sulfite reductase.
Journal of Biomolecular NMR (2001) 21(1): 71-2
Sibille, N., Pardi, A., Simorre, J. P. and Blackledge, M.
Refinement of Local and Long-Range Structural Order in Theophylline- Binding RNA Using (13)C-(1)H Residual Dipolar Couplings and Restrained Molecular Dynamics.
Journal of the American Chemical Society (2001) 123(49): 12135-12146.
Tsan, P., Caffrey, M., Daku, M. L., Cusanovich, M., Marion, D. and Gans, P.
Magnetic susceptibility tensor and heme contact shifts determinations in the Rhodobacter capsulatus ferricytochrome c ’: NMR and magnetic susceptibility studies.
Journal of the American Chemical Society (2001) 123(10): 2231-2242.
Publications 2000
Auge, S., Bersch, B., Tropis, M. and Milon, A.
Characterization of substance P-membrane interaction by transferred nuclear Overhauser effect.
Biopolymers (2000) 54(5): 297-306
Bersch, B., Blackledge, M, Brutscher, B., Cordier, JC, Hus, J. C. and Marion, D
Protein structure and dynamics by NMR in solution in Proteome and protein analysis. Springer, Berlin.(2000).: 91-116
Boisbouvier J, Blackledge M, Sollier A and Marion D
Simultaneous determination of disulphide bridge topology and three- dimensional structure using ambiguous intersulphur distance restraints: possibilities and limitations
Journal of Biomolecular NMR (2000) 16(3): 197-208
Boisbouvier, J., Brutscher, B., Pardi, A., Marion, D. and Simorre, J. P.
NMR determination of sugar puckers in nucleic acids from CSA-dipolar cross-correlated relaxation.
Journal of the American Chemical Society (2000) 122(28): 6779-6780
Brutscher, B.
Principles and applications of cross-correlated relaxation in biomolecules.
Concepts in Magnetic Resonance (2000) 12(4): 207-229
Demene, H., Tsan, P., Gans, P. and Marion, D.
NMR determination of the magnetic susceptibility anisotropy of cytochrome c ’ of Rhodobacter capsulatus by (1)J(HN) dipolar coupling constants measurement: Characterization of its monomeric state in solution.
Journal of Physical Chemistry B (2000) 104(11): 2559-2569.
Deprez, C., Blanchard, L., Simorre, J. P., Gavioli, M., Guerlesquin, F., Lazdunski, C., Lloubes, R. and Marion, D.
Assignment of the 1H, 15N and 13C resonances of the C-terminal domain of the TolA protein of Escherichia coli, involved in cell envelope integrity [letter]
Journal of Biomolecular NMR (2000) 18(2): 179-80
Dosset, P., J. C. Hus, M. Blackledge and D. Marion
Efficient analysis of macromolecular rotational diffusion from heteronuclear relaxation data.
Journal of Biomolecular NMR (2000) 16(1): 23-8.
Favier, A., Chapon, D., Fries, P. H., Rast, S. and Belorizky, E.
Comment on the intermolecular relaxation dispersion at 400, 600, 800 MHz of the (CH3)(4)N+ protons in D2O solutions with paramagnetic [Gd(D2O)(8)](3+) complexes.
Chemical Physics Letters (2000) 320(1-2): 49-52
Guilhaudis, L., J. P. Simorre, M. Blackledge, D. Marion, P. Gans, M. Neuburger and R. Douce
Combined Structural and Biochemical Analysis of the H-T Complex in the Glycine Decarboxylase Cycle: Evidence for a Destabilization Mechanism of the H-Protein.B
Biochemistry (2000) 39(15): 4259-4266.
Hus JC, Marion D and Blackledge M
De novo determination of protein structure by NMR using orientational and long-range order restraints
Journal of Molecular Biology (2000) 298(5): 927-36
Lancelin, J. M., Guilhaudis, L., Krimm, I., Blackledge, M. J., Marion, D. and Jacquot, J. P.
NMR structures of thioredoxin m from the green alga chlamydomonas reinhardtii
Proteins (2000) 41(3): 334-49
Tillett, M. L., Blackledge, M. J., Derrick, J. P., Lian, L. Y. and Norwood, T. J.
Overall rotational diffusion and internal mobility in domain II of protein G from Streptococcus determined from 15N relaxation data.
Protein Science (2000) 9(6): 1210-6.
Tsan, P., Hus, J. C., Caffrey, M., Marion, D. and Blackledge, M.
Rotational diffusion anisotropy and local backbone dynamics of carbon monoxide-bound Rhodobacter capsulatus cytochrome c’
Journal of the American Chemical Society (2000) 122(23): 5603-5612.
Vanbelle, C., Muhle-Goll, C., Remy, M. H., Masson, J. M., Marion, D. and Brutscher, B.
1H, 13C, and 15N assignment of a bleomycin resistance protein in its native form and in a complex with Zn2+ ligated bleomycin [letter]
Journal of Biomolecular NMR (2000) 18(2): 177-8
|
