High throughput membrane protein crystallization

Presentation

A high throughput membrane protein crystallization platform is being established at the IBS. It will comprise robotic systems with advanced imaging capabilities for in meso-crystallization of membrane proteins. The platform will include a UV microscope for testing crystallization probes, and will enable high-throughput crystallization with the capacity to store samples at different temperatures. The platform will facilitate the use of very small (about 10 nl) probes for crystallization and will be equipped with efficient systems for membrane protein crystallization.

This platform should considerably enhance the rate of success in crystallizing membrane proteins, and in particular human proteins which are often available in relatively small amounts.

Key words

Structural Biology, high-throughput crystallization, in meso crystallization, membrane proteins, lipidic cubic phase

Contact

Gordeliy Valentin

Dedicated staff

• Gordeliy Valentin
• Moiseeva Ekaterina
• Borshchevskiy Valentin

Specific equipment

Robot for in meso membrane protein crystallization, automated system for imaging crystallization probes, UV microscope for visualization of protein crystals, temperature controlled storing boxes for crystallization probes.

Access mode

Open access to internal and external users.

Cost

Contact Valentin Gordeliy for details related to costing.

Location

IBS/LPM

How to make a request?

Access can be requested by email to Valentin Gordeliy

Additional information