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Institut de Biologie StructuraleGrenoble / France

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Publications depuis 2015

La liste des publications du groupe parues dans des revues à comité de lecture depuis 2015, ainsi que les ouvrages et chapitres d’ouvrage, est consultable ici (données issues de HAL-IBS).

Publications jusqu’à 2014

Publications 2014

Discola KF, Forster A, Boulay F, Simorre JP, Attree I, Dessen A, and Job V
Membrane and chaperone recognition by the major translocator protein PopB of the type III secretion system of Pseudomonas aeruginosa.
J Biol. Chem 289:3591-­‐3601

Flayhan A, Vellieux FM, Lurz R, Maury O, Contreras-­‐Martel C, Girard E, Boulanger P, Breyton C
Crystal structure of pb9, the distal protein of bacteriophage T5 : a conserved structural motif among all siphophages.
J. Virol 88:820-­‐828

Lebreton A, Job V, Ragon M, Le Monnier A, Dessen A, Cossart P, and Bierne H
Structural basis for the inhibition of the chromatin receptor BAHD1 by the bacterial nucleomodulin LntA.
MBio 5 : e00775-­‐e00713

Nikolaidis I, Favini-Stabile S, Dessen A.
Resistance to antibiotics targeted to the bacterial cell wall.
Protein Science, Wiley-Blackwell, 23 (3), pp.243-59

Shaik, MM, Maccagni, A, Tourcier, G, Di Guilmi, AM, and Dessen, A
Structural basis of pilus anchoring by the ancillary pilin RrgC of Streptococcus pneumoniae.
J. Biol. Chem. 289 : 16988-­‐16997

Tosi, T, Estrozi, LF, Job, V, Guilvout, I, Pugsley, AP, Schoehn, G, and Dessen, A
Structural similarity of secretins from type II and type III secretion systems.
Structure 22 : 1348-­‐1355.

Wong, SG and Dessen, A
Structure of a bacterial a2-­‐macroglobulin reveals mimicry of eukaryotic innate immunity.
Nature Comm. 5, 4917

Publications 2013

Favini-Stabile S, Contreras-Martel C, Thielens N and Dessen A
MreB and MurG as scaffolds for the cytoplasmic steps of peptidoglycan biosynthesis.
Environmental Microbiology (2013) 15(12) : 3218-3228

Hrast M, Turk S, Sosič I, Knez D, Randall CP, Barreteau H, Contreras-Martel C, Dessen A, O’Neill AJ, Mengin-Lecreulx D, Blanot D and Gobec S
Structure–activity relationships of new cyanothiophene inhibitors of the essential peptidoglycan biosynthesis enzyme MurF.
European Journal of Medicinal Chemistry (2013) 66 : 32-45

Lombardi C, Ayach M, Beaurepaire L, Chenon M, Andreani J, Guerois R, Jupin I and Bressanelli S
A compact viral processing proteinase/ubiquitin hydrolase from the OTU family.
PLoS Pathogens (2013) 9(8) : e1003560

Neves D, Job V, Dortet L, Cossart P and Dessen A
Structure of Internalin InlK from the Human Pathogen Listeria monocytogenes.
Journal of Molecular Biology (2013) 425(22) : 4520–4529

Ruane KM, Lloyd AJ, Fulop V, Dowson CG, Barreteau H, Boniface A, Dementin S, Blanot D, Mengin-Lecreulx D, Gobec S, Dessen A and Roper DI
Specificity determinants for lysine incorporation in Staphylococcus aureus peptidoglycan as revealed by the structure of a MurE enzyme ternary complex.
Journal of Biological Chemistry (2013) 288(46) : 33439-33448

Tosi T, Pflug A, Discola KF, Neves D and Dessen A
Structural basis of eukaryotic cell targeting by type III secretion system (T3SS) effectors.
Research in Microbiology (2013) 164(6) : 605-619

Publications 2012

El Mortaji L, Contreras-Martel C, Moschioni M, Ferlenghi I, Manzano C, Vernet T, Dessen A and Di Guilmi AM
The full-length Streptococcus pneumoniae major pilin RrgB crystallizes in a fiber-like structure, which presents the D1 isopeptide bond and provides details on the mechanism of pilus polymerization.
Biochemical Journal (2012) 441(3) : 833-841

Gendrin C, Contreras-Martel C, Bouillot S, Elsen S, Lemaire D, Skoufias DA, Huber P, Attree I and Dessen A
Structural basis of cytotoxicity mediated by the type III secretion toxin exoU from Pseudomonas aeruginosa.
PLoS Pathogens (2012) 8(4) : e1002637

Hrast M, Turk S, Sosič I, Knez D, Randall CP, Barreteau H, Contreras-Martel C, Dessen A, O’Neill AJ, Mengin-Lecreulx D, Blanot D and Gobec S
Structure–activity relationships of new cyanothiophene inhibitors of the essential peptidoglycan biosynthesis enzyme MurF.
European Journal of Medicinal Chemistry (2013) 66 : 32-45

Inglis SR, Strieker M, Rydzik AM, Dessen A and Schofield CJ
A boronic-acid-based probe for fluorescence polarization assays with penicillin binding proteins and beta-lactamases.
Analytical Biochemistry (2012) 420(1) : 41-47

Neves D and Dessen A
Microbiology : sensing stability.
Nature Chemical Biology (2012) 8(8) : 681-682

Neves D, Estrozi LF, Job V, Gabel F, Schoehn G and Dessen A
Conformational states of a bacterial alpha(2)-macroglobulin resemble those of human complement C3.
PLoS One (2012) 7(4) : e35384

Nikolaidis I, Izore T, Job V, Thielens N, Breukink E and Dessen A
Calcium-dependent complex formation between PBP2 and lytic transglycosylase SltB1 of Pseudomonas aeruginosa.
Microbial Drug Resistance (2012) 18(3) : 298-305

Tomašić T, Šink R, Zidar N, Fic A, Contreras-Martel C, Dessen A, Patin D, Blanot D, Müller-Premru M, Gobec S, Zega A, Kikelj D and Mašič LP
Dual inhibitor of MurD and MurE ligases from escherichia coli and staphylococcus aureus.
ACS Medicinal Chemistry Letters (2012) 3(8) : 626-630

Publications 2011

Contreras-Martel C, Amoroso A, Woon EC, Zervosen A, Inglis S, Martins A, Verlaine O, Rydzik AM, Job V, Luxen A, Joris B, Schofield CJ and Dessen A
Structure-guided design of cell wall biosynthesis inhibitors that overcome beta-Lactam resistance in Staphylococcus aureus (MRSA).
ACS Chemical Biology (2011) 6 (9) : 943-951

Contreras Martel C, El Mortaji L, Manzano C, Terrasse R, Vernet T, Di Guilmi AM and Dessen A
Structural basis of host cell recognition by the pilus adhesin from Streptococcus pneumonia.
Structure (2011) 18 (1) : 106-115

El Ghachi M, Mattei PJ, Ecobichon C, Martins A, Hoos S, Schmitt C, Colland F, Ebel C, Prevost MC, Gabel F, England P, Dessen A and Boneca IG
Characterization of the elongasome core PBP2 : MreC complex of Helicobacter pylori.
Molecular Microbiology (2011) 82 (1) : 68-86

Inglis SR, Strieker M, Rydzik AM, Dessen A and Schofield CJ
A boronic-acid-based probe for fluorescence polarization assays with penicillin binding proteins and β-lactamases.
Analytical Biochemistry (2011) 420 : 41-47

Izoré T, Job V and Dessen A
Biogenesis, regulation, and targeting of the type III secretion system.
Structure (2011) 19 (5) : 603-612

Izoré T, Perdu C, Job V, Atree I, Faudry E and Dessen A
Structural characterization and membrane localization of ExsB from the type III secretion system (T3SS) of Pseudomonas aeruginosa.
Journal of Molecular Biology (2011) 413 (1) : 236-246

Lebreton A, Lakisic G, Job V, Fritsch L, Tham TN, Camejo A, Mattei PJ, Regnault B, Nahori MA, Cabanes D, Gautreau A, Ait-Si-Ali S, Dessen A, Cossart P and Bierne H
A bacterial protein targets the BAHD1 chromatin complex to stimulate type III interferon response.
Science (2011) 331 (6022) : 1319-1321

Macheboeuf P, Piuzzi M, Finet S, Bontems F, Pérez J, Dessen A and Vachette P
Solution X-ray scattering study of a full-length class A penicillin-binding protein.
Biochemical and Biophysical Research Communications (2011) 405 (1) : 107-111

Mattei PJ, Faudry E, Job V, Izore T, Attree I and Dessen A
Membrane targeting and pore formation by the type III secretion system translocon.
FEBS Journal (2011) 278(3) : 414-426

Nickerson NN, Tosi T, Dessen A, Baron B, Raynal B, England P and Pugsley AP
Outer membrane targeting of secretin PulD relies on disordered domain recognition by a dedicated chaperone.
Journal of Biological Chemistry (2011) 286 (45) : 38833-38843

Sosic I, Barreteau H, Simcic M, Roman S, Cesar J, Zega A, Golic Grdadolnik S, Contreras-Martel C, Dessen A, Amoroso A, Joris B, Blanot D and Gobec S
Second-generation sulfonamide inhibitors of Dglutamic acid-adding enzyme : activity optimisation with conformationally rigid analogues of dglutamic acid.
European Journal of Medicinal Chemistry (2011) 46 (7) : 2880-2894

Szeto TH, Dessen A and Pelicic V
Structure/function analysis of Neisseria meningitidis PilW, a conserved protein that plays multiple roles in type IV pilus biology.
Infection and Immunity (2011) 79 (8) : 3028-3035

Tomašić T, Zidar N, Šink R, Kovač A, Blanot D, Contreras-Martel C, Dessen A, Müller-Premru M, Zega A, Gobec S, Kikelj D and Peterlin Mašič L
Structure-based design of a new series of d-glutamic acid based inhibitors of bacterial UDP-N-acetylmuramoyl-l-alanine : D-glutamate ligase (MurD).
Journal of Medicinal Chemistry (2011) 54 (13) : 4600-4610

Tosi T, Nickerson NN, Mollica L, Jensen MR, Blackledge M, Baron B, England P, Pugsley AP and Dessen A
Pilotin-secretin recognition in the type II secretion system of Klebsiella oxytoca.
Molecular Microbiology (2011) 82 (6) : 1422-1432

Publications 2010

Aschtgen MS, Gavioli M, Dessen A, Lloubes R and Cascales E
The SciZ protein anchors the enteroaggregative Escherichia coli Type VI secretion system to the cell wall.
Molecular Microbiology (2010) 75(4) : 886-899.

Dessen A and Xu W
Structural biology of protein functional regulation.
Current Opinion in Structural Biology (2010) 20(6) : 711-713

El Mortaji L, Terrasse R, Dessen A, Vernet T and Di Guilmi AM
Stability and assembly of pilus subunits of streptococcus pneumoniae.
Journal of Biological Chemistry (2010) 285(16) : 12405-12415.

Gendrin C, Sarrazin S, Bonnaffe D, Jault JM, Lortat-Jacob H and Dessen A
Hijacking of the pleiotropic cytokine interferon-gamma by the type III secretion system of Yersinia pestis.
PLoS One (2010) 5(12) : e15242

Izoré T, Contreras-Martel C, El Mortaji L, Manzano C, Terrasse R, Vernet T, Di Guilmi AM and Dessen A
Structural basis of host cell recognition by the pilus adhesin from Streptococcus pneumoniae.
Structure (2010) 18(1) : 106-115.

Job V, Mattei PJ, Lemaire D, Attree I and Dessen A
Structural basis of chaperone recognition of type III secretion system minor translocator proteins.
Journal of Biological Chemistry (2010) 285(30) : 23224-23232.

Matteï P-J, Neves D and Dessen A
Bridging cell wall biosynthesis and bacterial morphogenesis.
Current Opinion in Structural Biology (2010) 20(6) : 749-755

Ple S, Job V, Dessen A and Attree I
Co-chaperone interactions in export of the type III needle component PscF of Pseudomonas aeruginosa
Journal of Bacteriology (2010) 192(14) : 3801-3808.

Zidar N, Tomasic T, Sink R, Rupnik V, Kovac A, Turk S, Patin D, Blanot D, Contreras Martel C, Dessen A, Muller Premru M, Zega A, Gobec S, Peterlin Masic L and Kikelj D
Discovery of novel 5-benzylidenerhodanine and 5-benzylidenethiazolidine-2,4-dione inhibitors of MurD ligase.
Journal of Medicinal Chemistry (2010) 53(18) : 6584-6594

Publications 2009

Contreras-Martel C, Dahout-Gonzalez C, Martins Ados S, Kotnik M and Dessen A
PBP active site flexibility as the key mechanism for beta-lactam resistance in pneumococci.
Journal of Molecular Biology (2009) 387(4) : 899-909.

Manzano C, Izore T, Job V, Di Guilmi AM and Dessen A
Sortase activity is controlled by a flexible lid in the pilus biogenesis mechanism of gram-positive pathogens.
Biochemistry (2009) 48(44) : 10549-10557.

Neiers F, Madhurantakam C, Fälker S, Manzano C, Dessen A, Normark S, Henriques-Normark B and Achour A
Two crystal structures of Pneumococcal pilus sortase C provide novel insights into catalysis and substrate specificity.
Journal of Molecular Biology (2009) 393 : 704-716.

Publications 2008

Manzano C, Contreras-Martel C, El Mortaji L, Izoré T, Fenel D, Vernet T, Schoehn G, Di Guilmi AM, Dessen A
_Sortase-mediated pilus fiber biogenesis in Streptococcus pneumoniae.
Structure (2008) Dec 10 ;16(12):1838-48.

Diemer H, Elias M, Renault F, Rochu D, Contreras-Martel C, Schaeffer C, Van Dorsselaer A and Chabriere E
Tandem use of X-ray crystallography and mass spectrometry to obtain ab initio the complete and Journal of Molecular Biology (2008) 378(5) : 1031-1039
exact amino acids sequence of HPBP, a human 38-kDa apolipoprotein.
Proteins (2008) 71(4) : 1708-1720

Humljan J, Kotnik M, Contreras-Martel C, Blanot D, Urleb U, Dessen A, Solmajer T and Gobec S
Novel naphthalene-N-sulfonyl-D-glutamic acid derivatives as inhibitors of MurD, a key peptidoglycan biosynthesis enzyme.
J Med Chem (2008) 51(23) : 7486-7494

Job V, Carapito R, Vernet T, Dessen A and Zapun A
Common alterations in PBP1a from resistant Streptococcus pneumoniae decrease its reactivity toward beta-lactams : STRUCTURAL INSIGHTS.
Journal of Biological Chemistry (2008) 283(8) : 4886-4894

Macheboeuf P, Lemaire D, Dos Santos Martins A, Dideberg O, Jamin M and Dessen A
Trapping of an acyl-enzyme intermediate in a Penicillin-Binding Protein (PBP)-catalyzed reaction.
Journal of Molecular Biology (2008) 276(2) : 405-413

Trindade MB, Job V, Contreras-Martel C, Pelicic V and Dessen A
Structure of a widely conserved type IV pilus biogenesis factor that affects the stability of secretin multimers.
Molecular Biology (2008) 378(5):1031-1039

Publications 2007

Contreras-Martel C, Matamala A, Bruna C, Poo-Caamano G, Almonacid D, Figueroa M, Martinez-Oyanedel J and Bunster M
The structure at 2 A resolution of Phycocyanin from Gracilaria chilensis and the energy transfer network in a PC-PC complex.
Biophysical Chemistry (2007) 125(2-3) : 388-396

Faudry E, Job V, Dessen A, Attree I and Forge V
Type III secretion system translocator has a molten globule conformation both in its free and chaperone-bound forms.
Febs Journal (2007) 274(14) : 3601-3610

Kotnik M, Humljan J, Contreras-Martel C, Oblak M, Kristan K, Herve M, Blanot D, Urleb U, Gobec S, Dessen A and Solmajer T
Structural and functional characterization of enantiomeric glutamic acid derivatives as potential transition state analogue inhibitors of MurD ligase.
Journal of Molecular Biology (2007) 370(1) : 107-115

Macheboeuf P, Fischer DS, Brown T, Jr., Zervosen A, Luxen A, Joris B, Dessen A and Schofield CJ
Structural and mechanistic basis of penicillin-binding protein inhibition by lactivicins.
Nature Chemical Biology (2007) 3(9) : 565-569

Morales R, Berna A, Carpentier P, Contreras-Martel C, Renault F, Nicodeme M, Chesne-Seck ML, Bernier F, Dupuy J, Schaeffer C, Diemer H, Van-Dorsselaer A, Fontecilla-Camps JC, Masson P, Rochu D and Chabriere E
[Discovery and crystallographic structure of human apolipoprotein].
Annales Pharmaceutiques Françaises (2007) 65(2) : 98-107

Quinaud M, Ple S, Job V, Contreras-Martel C, Simorre JP, Attree I and Dessen A
Structure of the heterotrimeric complex that regulates type III secretion needle formation.
Proceedings of the National Academy of Sciences U S A (2007) 104(19) : 7803-7808

Publications 2006

Cavazza C, Contreras-Martel C, Pieulle L, Chabriere E, Hatchikian EC and Fontecilla-Camps JC
Flexibility of thiamine diphosphate revealed by kinetic crystallographic studies of the reaction of pyruvate-ferredoxin oxidoreductase with pyruvate.
Structure (2006) 14(2) : 217-224

Contreras-Martel C, Carpentier P, Morales R, Renault F, Chesne-Seck ML, Rochu D, Masson P, Fontecilla-Camps JC and Chabriere E
Crystallization and preliminary X-ray diffraction analysis of human phosphate-binding protein.
Acta Crystallographica Section F : Structural Biology and Crystallization Communications (2006) 62(Pt 1) : 67-69

Contreras-Martel C, Job V, Di Guilmi AM, Vernet T, Dideberg O and Dessen A
Crystal structure of penicillin-binding protein 1a (PBP1a) reveals a mutational hotspot implicated in beta-lactam resistance in Streptococcus pneumoniae.
Journal of Molecular Biology (2006) 355(4) : 684-696

Macheboeuf P, Contreras-Martel C, Job V, Dideberg O and Dessen A
Penicillin binding proteins : key players in bacterial cell cycle and drug resistance processes.
FEMS Microbiology Reviews (2006) 30(5) : 673-691

Morales R, Berna A, Carpentier P, Contreras-Martel C, Renault F, Nicodeme M, Chesne-Seck ML, Bernier F, Dupuy J, Schaeffer C, Diemer H, Van-Dorsselaer A, Fontecilla-Camps JC, Masson P, Rochu D and Chabriere E
Serendipitous discovery and x-ray structure of a human phosphate binding apolipoprotein.
Structure (2006) 14(3) : 601-609

Publications 2005

Macheboeuf P, di Guilmi AM, Job V, Vernet T, Dideberg O and Dessen A
Active site restructuring regulates ligand recognition in class A penicillin-binding proteins (PBPs).
Proceedings of the National Academy of Sciences U S A (2005) 102(3) : 577-582

Morlot C, Pernot L, Le Gouellec A, di Guilmi AM, Vernet T, Dideberg O and Dessen A
Crystal structure of a peptidoglycan synthesis regulatory factor (PBP3) from Streptococcus pneumoniae.
Journal of Biological Chemistry (2005) 280(16) : 15984-15991

Quinaud M, Chabert J, Faudry E, Neumann E, Lemaire D, Pastor A, Elsen S, Dessen A and Attree I
The PscE-PscF-PscG complex controls type III secretion needle biogenesis in Pseudomonas aeruginosa.
Journal of Biological Chemistry (2005) 280(43) : 36293-36300

Publications 2004

Dessen A
A new catalytic dyad regulates anchoring of molecules to the gram-positive cell wall by sortases.
Structure (Camb) (2004) 12(1) : 6-7

Goure J, Pastor A, Faudry E, Chabert J, Dessen A and Attree I
The V antigen of Pseudomonas aeruginosa is required for assembly of the functional PopB/PopD translocation pore in host cell membranes.
Infection Immunity (2004) 72(8) : 4741 - 4750

Nanao MH, Tcherniuk SO, Chroboczek J, Dideberg O, Dessen A and Balakirev MY
Crystal structure of human otubain 2.
EMBO Reports (2004) 5(8) : 783-788

Pernot L, Chesnel L, Legouellec A, Croize J, Vernet T, Dideberg O and Dessen A
A PBP2x from a clinical isolate of spectrococcus pneumoniae exhibits an alternative mechanism for reduction of susceptibility to beta-lactam antibiotics.
Journal of Biological Chemistry (2004) 279 : 16463-16470

Publications 2003

Di Guilmi AM, Dessen A, Dideberg O and Vernet T
Functional characterization of penicillin-binding protein 1b from Streptococcus pneumoniae.
Journal of Bacteriology (2003) 185(5) : 1650-1658.

Di Guilmi AM, Dessen A, Dideberg O and Vernet T
The glycosyltransferase domain of penicillin-binding protein 2a from Streptococcus pneumoniae catalyzes the polymerization of murein glycan chains.
Journal of Bacteriology (2003) 185(15) : 4418-4423

Fokine A, Morales R, Contreras-Martel C, Carpentier P, Renault F, Rochu D and Chabriere E
Direct phasing at low resolution of a protein copurified with human paraoxonase (PON1).
Acta Crystallographica D Biological Crystallography (2003) 59(Pt 12) : 2083-2087

Job V, Di Guilmi AM, Martin L, Vernet T, Dideberg O and Dessen A
Structural studies of the transpeptidase domain of PBP1a from Streptococcus pneumoniae.
Acta Crystallographica D Biological Crystallography (2003) 59(6) : 1067-1069

Molla G, Motteran L, Job V, Pilone MS and Pollegioni L
Kinetic mechanisms of glycine oxidase from Bacillus subtilis.
European Journal of Biochemistry (2003) 270(7) : 1474-1482

Nanao M, Ricard-Blum S, Di Guilmi AM, LeMaire D, Lascoux D, Chabert J, Attree I and Dessen A
Type III secretion proteins PcrV and PcrG from Pseudomonas aeruginosa form a 1:1 complex through high affinity interactions.
BMC Microbiology (2003) 3 : 21

Schoehn G, Di Guilmi AM, Lemaire D, Attree I, Weissenhorn W and Dessen A
Oligomerization of type III secretion proteins PopB and PopD precedes pore.
Embo Journal(2003) 22(19) : 4957-4967

Publications 2002

Boselli A, Sacchi S, Job V, Pilone MS and Pollegioni L
Role of tyrosine 238 in the active site of Rhodotorula gracilis D-amino acid oxidase. A site-directed mutagenesis study.
European Journal of Biochemistry (2002) 269(19) : 4762-4771

Di Guilmi AM and Dessen A
New approaches towards the identification of antibiotic and vaccine targets in Streptococcus pneumoniae.
EMBO Reports (2002) 3(8) : 728-734.

Di Guilmi AM, Dessen A, Dideberg O and Vernet T
Bifunctional penicillin-binding proteins : focus on the glycosyltransferase domain and its specific inhibitor moenomycin.
Current Pharmacology Biotechnology (2002) 3(2) : 63-75.

Job V, Molla G, Pilone MS and Pollegioni L
Overexpression of a recombinant wild-type and His-tagged Bacillus subtilis glycine oxidase in Escherichia coli.
European Journal of Biochemistry (2002) 269(5) : 1456-1463

Publications 2001

Contreras Martel C, Martinez Oyanedel J, Bunster M, Legrand P, Piras C, Vernede X and Fontecilla Camps J C
Crystallization and 2.2 angstrom E resolution structure of R-phycoerythrin from Gracilaria chilensis : a case of perfect hemihedral twinning.
Acta Crystallographica D Biological Crystallography (2001) 57 Part 1 : 52-60

Dessen A, di Guilmi AM, Vernet T and Dideberg O
Molecular mechanisms of antibiotic resistance in Gram-positive pathogens.
Current Drug Targets - Infectious Disorders (2001) 1 : 63-77

Dessen A, Mouz N, Gordon E, Hopkins J and Dideberg O
Crystal Structure of PBP2x from a Highly Penicillin-resistant Streptococcus pneumoniae Clinical Isolate. A MOSAIC FRAMEWORK CONTAINING 83 MUTATIONS.
Journal of Biological Chemistry (2001) 276(48) : 45106-45112.

Publications 2000

Dessen A
Phospholipase A(2) enzymes : structural diversity in lipid messenger metabolism.
Structure Folding & Design (2000) 8(2) : R15-22.

Dessen A
Structure and mechanism of human cytosolic phospholipase A(2).
Biochimica and Biophysica Acta (2000) 1488(1-2) : 40-47.

Dessen A, Forest E, Volchkov V, Dolnik O, Klenk HD and Weissenhorn W
Crystallization and preliminary X-ray analysis of the matrix protein from Ebola virus.
Acta Crystallographica D Biological Crystallography (2000) 56(Pt 6) : 758-760.

Dessen A, Volchkov V, Dolnik O, Klenk HD and Weissenhorn W
Crystal structure of the matrix protein VP40 from Ebola virus.
Embo Journal (2000) 19(16) : 4228-4236.

Molla G, Porrini D, Job V, Motteran L, Vegezzi C, Campaner S, Pilone MS and Pollegioni L
Role of arginine 285 in the active site of Rhodotorula gracilis D-amino acid oxidase. A site-directed mutagenesis study.
Journal of Biological Chemistry (2000) 275(32) : 24715-24721

Ruigrok RW, Schoehn G, Dessen A, Forest E, Volchkov V, Dolnik O, Klenk HD and Weissenhorn W
Structural characterization and membrane binding properties of the matrix protein VP40 of Ebola virus.
Journal of Molecular Biology (2000) 300(1) : 103-112.

Somoza JR, Menon S, Schmidt H, Joseph-McCarthy D, Dessen A, Stahl ML, Somers WS and Sullivan FX
Structural and kinetic analysis of Escherichia coli GDP-mannose 4,6 dehydratase provides insights into the enzyme’s catalytic mechanism and regulation by GDP-fucose.
Structure Folding & Design (2000) 8(2) : 123-135.