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Institut de Biologie StructuraleGrenoble / France

Publications depuis 2015

La liste des publications du groupe parues dans des revues à comité de lecture depuis 2015 est consultable ici (données issues de HAL-IBS).

Publications jusqu’en 2014

Publications 2014

Appolaire A, Durá MA, Ferruit M, Andrieu JP, Godfroy A, Gribaldo S and Franzetti B
The TET2 and TET3 aminopeptidases from Pyrococcus horikoshii form a hetero-subunit peptidasome with enhanced peptide destruction properties.
Mol. Microbiol. 94(4):803-14.

Gaboriaud C, Ling WL, Thielens NM, Bally I and Rossi V
Deciphering the fine details of C1 assembly and activation mechanisms : mission impossible ?
Front. Immunol. 5:565 (pp 1-7).

Laffly E, Lacroix M, Martin L, Vassal-Stermann E, Thielens NM and Gaboriaud C
Human ficolin-2 recognition versatility extended : an update on its binding to sulphated/phosphated carbohydrates.
FEBS Lett. 588, 4694-4700.

Reiser J-B, Legoux F, Gras S, Trudel E, Chouquet A, Léger A, Le Gorrec M, Machillot P, Bonneville M, Saulquin X and Housset D
Analysis of relationships between peptide/MHC structural features and naïve T cell frequency in humans.
J. Immunol. 193 : 5816-5826.

Rossi V, Bally I, Lacroix M, Arlaud GJ and Thielens NM
Classical complement pathway components c1r and c1s : purification from human serum and in recombinant form and functional characterization.
Methods Mol Biol 1100, 43-­60

Sosoniuk E, Vallejos G, Kenawy H, Gaboriaud C, Thielens N, Fujita T, Schwaeble W, Ferreira A and Valck C
Trypanosomacruzi calreticulin inhibits the complement lectin pathway activation by direct interaction with L-­‐Ficolin.
Molecular Immunology 60, 80-­‐85.

Vassal-Stermann E, Lacroix M, Gout E, Laffly E, Pedersen CM, Martin L, Amoroso A, Schmidt RR, Zähringer U, Gaboriaud C, Di Guilmi A-M and Thielens NM
Human L-ficolin recognizes phosphocholine moieties of pneumococcal teichoic acid.
J. Immunol. 193, 5699-5708.

Verneret M, Tacnet-­‐Delorme P, Osman R, Awad R, Grichine A, Kleman JP, Frachet P
Relative Contribution of C1q and Apoptotic Cell-­‐Surface Calreticulin to Macrophage Phagocytosis.
Journal of Innate Immunity Doi : 10.1159/000358834

Publications 2013

Bally I, Ancelet S, Moriscot C, Gonnet F, Mantovani A, Daniele R,
Schoehn G, Arlaud GJ, and Thielen NM

Expression of recombinant human complement C1q allows identification of the C1r/C1s-binding sites.
Proceedings of the National Academy of Sciences (2013) 110(21) : 8650-8655

Berland S, Ma Y, Marie A, Andrieu JP, Bedouet L and Feng Q
Proteomic and profile analysis of the proteins laced with aragonite and vaterite in the freshwater mussel Hyriopsis cumingii shell biominerals.
Protein Peptide Letters (2013) 20(10) : 1170-1180

Bourhis JM, Vadon-Le Goff S, Afrache H, Mariano N, Kronenberg D, Thielens N, Moali C and Hulmes DJS
Procollagen C-proteinase enhancer grasps the stalk of the C-propeptide trimer to boost collagen precursor maturation.
Proceedings of the National Academy of Sciences (2013) 110(16) : 6394-6399

Candat A, Poupart P, Andrieu J-P, Chevrollier A, Reynier P, Rogniaux H, Avelange-Macherel M-H and Macherel D
Experimental determination of organelle targeting peptide cleavage sites using transient expression of GFP translational fusions.
Analytical Biochemistry (2013) 434(1) : 44–51

Favini-Stabile S, Contreras-Martel C, Thielens N and Dessen A
MreB and MurG as scaffolds for the cytoplasmic steps of peptidoglycan biosynthesis.
Environmental Microbiology (2013) 15(12) : 3218-3228

Gaboriaud C, Gupta RK, Martin L, Lacroix M, Serre L, Teillet F, Arlaud GJ, Rossi V and Thielens NM
The serine protease domain of MASP-3 : enzymatic properties and crystal structure in complex with ecotin.
PLoS One (2013) 8(7) : e67962

Henriksen ML, Brandt J, Andrieu JP, Nielsen C, Jensen PH, Holmskov U, Jorgensen TJ, Palarasah Y, Thielens NM and Hansen S
Heteromeric complexes of native collectin kidney 1 and collectin liver 1 are found in the circulation with MASPs and activate the complement system.
Journal of Immunology (2013) 191(12) : 6117-6127

Henriksen ML, Brandt J, Iyer SS, Thielens NM and Hansen S
Characterization of the interaction between collectin 11 (CL-11, CL-K1) and nucleic acids.
Molecular Immunology (2013) 56(4) : 757-767

Jacquet M, Lacroix M, Ancelet S, Gout E, Gaboriaud C, Thielens NM and Rossi V
Deciphering complement receptor Type 1 interactions with recognition proteins of the lectin complement pathway.
Journal of Immunology (2013) 190(7) : 3721-3731

Joseph K, Kulik L, Coughlin B, Kunchithapautham K, Bandyopadhyay M, Thiel S, Thielens NM, Holers VM and Rohrer B
Oxidative stress sensitizes Retinal Pigmented Epithelial (RPE) cells to complement-mediated injury in a natural antibody-, lectin pathway-, and phospholipid epitope-dependent manner.
Journal of Biological Chemistry (2013) 288(18) : 12753-12765

Ma Y, Berland S, Andrieu J-P, Feng Q and Bédouet L
What is the difference in organic matrix of aragonite vs. vaterite polymorph in natural shell and pearl ? Study of the pearl-forming freshwater bivalve mollusc Hyriopsis cumingii.
Materials Science and Engineering : C (2013) 33(3) : 1521-1529

Mauriello CT, Pallera HK, Sharp JA, Woltmann JL, Qian SZ, Hair PS, van der Pol P, van Kooten C, Thielens NM, Lattanzio FA, Cunnion KM and Krishna NK
A novel peptide inhibitor of classical and lectin complement activation including ABO incompatibility.
Molecular Immunology (2013) 53(1-2) : 132-139

Pederzoli-Ribeil M, Angelot F, Millet A, Kantari C, Reuter N, Mouthon L, Frachet P, Saas P and Witko-Sarsat V
Proteinase 3 (PR3) is a phosphatidylserine-binding protein that can bind microparticles : Relevance in the context of granulomatosis with polyangiitis (GPA).
La Presse Médicale (2013) 42(4, Part 2) : 652

Perino J, Thielens NM, Crouch E, Spehner D, Crance JM and Favier AL
Protective effect of surfactant protein d in pulmonary vaccinia virus infection : implication of A27 viral protein.
Viruses (2013) 5(3) : 928-953

Publications 2012

Broisat A, Hernot S, Toczek J, De Vos J, Riou LM, Martin S, Ahmadi M, Thielens N, Wernery U, Caveliers V, Muyldermans S, Lahoutte T, Fagret D, Ghezzi C and Devoogdt N
Nanobodies targeting mouse/human VCAM1 for the nuclear imaging of atherosclerotic lesions.
Circulation Research (2012) 110(7) : 927-937

Foucher AE, Reiser JB, Ebel C, Housset D and Jault JM
Potassium acts as a GTPase-activating element on each nucleotide-binding domain of the essential Bacillus subtilis EngA.
PLoS One (2012) 7(10) : e46795

Gabillet J, Millet A, Pederzoli-Ribeil M, Tacnet-Delorme P, Guillevin L, Mouthon L, Frachet P and Witko-Sarsat V
Proteinase 3, the autoantigen in granulomatosis with polyangiitis, associates with calreticulin on apoptotic neutrophils, impairs macrophage phagocytosis, and promotes inflammation.
Journal of Immunology (2012) 189(5) : 2574-2583

Gaboriaud C, Frachet P, Thielens N and Arlaud ǴJ
The human C1q globular domain : structure and recognition of non-immune self ligands.
Frontiers in Immunology (2012) 2(92) : 1-8

Gjelstrup LC, Kaspersen JD, Behrens MA, Pedersen JS, Thiel S, Kingshott P, Oliveira CL, Thielens NM and Vorup-Jensen T
The role of nanometer-scaled ligand patterns in polyvalent binding by large mannan-binding lectin oligomers.
Journal of Immunology (2012) 188(3) : 1292-1306

Laursen IA, Thielens NM, Christiansen M and Houen G
MASP interactions with plasma-derived MBL.
Molecular Immunology (2012) 52(2) : 79-87

Moreno-Amaral AN, Gout E, Danella-Polli C, Tabarin F, Lesavre P, Pereira-da-Silva G, Thielens NM and Halbwachs-Mecarelli L
M-ficolin and leukosialin (CD43) : new partners in neutrophil adhesion.
Journal of Leukocyte Biology (2012) 91(3) : 469-474

Nikolaidis I, Izore T, Job V, Thielens N, Breukink E and Dessen A
Calcium-dependent complex formation between PBP2 and lytic transglycosylase SltB1 of Pseudomonas aeruginosa.
Microbial Drug Resistance (2012) 18(3) : 298-305

Sevajol M, Reiser JB, Chouquet A, Perard J, Ayala I, Gans P, Kleman JP and Housset D
The C-terminal polyproline-containing region of ELMO contributes to an increase in the life-time of the ELMO-DOCK complex.
Biochimie (2012) 94(3) : 823-828

Siqueira-Silva J, Fenel D, Gout E, Yeda FP, Marinheiro JC, Barrella KM, Silva ML, Schoehn G, Harsi CM and Fender P
Generation and biological properties of a recombinant dodecahedron containing the short fiber protein of the human adenovirus 41.
Intervirology (2012) 55(5) : 349-355

Szolajska E, Burmeister WP, Zochowska M, Nerlo B, Andreev I, Schoehn G, Andrieu JP, Fender P, Naskalska A, Zubieta C, Cusack S and Chroboczek J
The structural basis for the integrity of adenovirus ad3 dodecahedron.
PLoS One (2012) 7(9) : e46075

Terrasse R, Tacnet-Delorme P, Moriscot C, Perard J, Schoehn G, Vernet T, Thielens NM, Di Guilmi AM and Frachet P
Human and pneumococcal cell surface GAPDH proteins are both ligands of human C1q.
Journal of Biological Chemistry (2012) 287(51) : 42620-42633

Publications 2011

Chouquet A, Paidassi H, Ling WL, Frachet P, Houen G, Arlaud GJ and Gaboriaud C
X-ray structure of the human calreticulin globular domain reveals a Peptide-binding area and suggests a multi-molecular mechanism.
PLoS One (2011) 6(3) : e17886

Gaboriaud C, Gregory-Pauron L, Teillet F, Thielens NM, Bally I and Arlaud GJ
Structure and properties of the Ca2+ -binding CUB domain, a widespread ligand-recognition unit involved in major biological functions.
Biochemical Journal (2011) 439 (2) : 185-193

Gabillet J, Pederzoli-Ribeil M, Kantari C, Guillevin L, Frachet P, Mouthon L and Witko-Sarsat V
Apoptosis-induced proteinase 3 membrane expression impaired apoptotic neutrophil clearance by interfering with the calreticulin "Eat-Me Signal" and trigger pro-inflammatory cytokines release.
Inflammation Research (2011) 60 : 81-81

Gout E, Moriscot C, Doni A, Dumestre-Perard C, Lacroix M, Perard J, Schoehn G, Mantovani A, Arlaud GJ and Thielens NM
M-Ficolin interacts with the long pentraxin PTX3 : A novel case of cross-talk between soluble pattern-recognition molecules.
Journal of Immunology (2011) 186 (10) : 5815-5822

Ling WL, Biro A, Bally I, Tacnet P, Deniaud A, Doris E, Frachet P, Schoehn G, Pebay-Peyroula E and Arlaud GJ
Proteins of the innate immune system crystallize on carbon nanotubes but are not activated.
ACS Nano (2011) 5 (2) : 730-737

Païdassi H, Tacnet-Delorme P, Verneret M, Gaboriaud C, Houen G, Duus K, Ling WL, Arlaud GJ and Frachet P
Investigations on the C1q-calreticulin-phosphatidylserine interactions yield new insights into apoptotic cell recognition.
Journal of Molecular Biology (2011) 408 (2) : 277-290

Thielens NM
The double life of M-ficolin : What functions when circulating in serum and tethered to leukocyte surfaces ?
Journal of Leukocyte Biology (2011) 90 (3) : 410-412

Publications 2010

Biro A, Ling WL and Arlaud GJ
Complement protein C1q recognizes enzymatically modified low-density lipoprotein through unesterified fatty acids generated by cholesterol esterase.
Biochemistry (2010) 49(10) : 2167-2176

Brier S, Pflieger D, Le Mignon M, Bally I, Gaboriaud C, Arlaud GJ and Daniel R
Mapping surface accessibility of the C1r/C1s tetramer by chemical modification and mass spectrometry provides new insights into assembly of the human C1 complex.
Journal of Biological Chemistry (2010) 285(42) : 32251-32263

Duus K, Hansen EW, Tacnet P, Frachet P, Arlaud GJ, Thielens NM and Houen G
Direct interaction between CD91 and C1q.
FEBS Journal (2010) 277(17) : 3526-3537

Duus K, Thielens NM, Lacroix M, Tacnet P, Frachet P, Holmskov U and Houen G
CD91 interacts with mannan-binding lectin (MBL) through the MBL-associated serine protease-binding site.
FEBS Journal (2010) 277(23) : 4956-4964

Erlich P, Dumestre-Perard C, Ling WL, Lemaire-Vieille C, Schoehn G, Arlaud GJ, Thielens NM, Gagnon J and Cesbron JY
Complement protein C1q forms a complex with cytotoxic prion protein oligomers.
Journal of Biological Chemistry (2010) 285(25) : 19267-19276

Fould B, Garlatti V, Neumann E, Fenel D, Gaboriaud C and Arlaud GJ
Structural and functional characterization of the recombinant human mitochondrial trifunctional protein.
Biochemistry (2010) 49(39) : 8608-8617

Gaboriaud C, Garlatti V, Chouquet A, Lunardi T, Païdassi H, Thielens NM and Arlaud GJ
C1q binds deoxyribose and heparan sulfate through neighboring sites of its recognition domain : Implications for the control of C1 activation upon recognition of non-immune targets.
Molecular Immunology (2010) 47(13) : 2255-2256

Garlatti V, Chouquet A, Lunardi T, Vives R, Paidassi H, Lortat-Jacob H, Thielens NM, Arlaud GJ and Gaboriaud C
Cutting edge : C1q binds deoxyribose and heparan sulfate through neighboring sites of its recognition domain.
Journal of Immunology (2010) 185(2) : 808-812

Garlatti V, Martin L, Lacroix M, Gout E, Arlaud G, Thielens N and Gaboriaud C
Structural insights into the recognition properties of human ficolins.
Journal of Innate Immunity (2010) 2 : 17-23

Gjelstrup LC, Thiel S, Kingshott P, Thielens N and Vorup-Jensen T
In-depth analysis by Biacore technology to evaluate the affinity versus avidity of the binding of the oligomeric pattern recognition molecule mannan-binding lectin.
Molecular Immunology (2010) 47(13) : 2263-2263

Gout E, Doni A, Lacroix M, Arlaud GJ, Mantovani A and Thielens NM
M-ficolin interacts with the long-chain pentraxin PTX3. A novel case of crosstalk between pattern recognition proteins ?
Molecular Immunology (2010) 47(13) : 2232-2233

Gout E, Garlatti V, Smith DF, Lacroix M, Dumestre-Pérard C, Lunardi T, Martin L, Cesbron JY, Arlaud GJ, Gaboriaud C and Thielens NM
Carbohydrate recognition properties of huma ficolins : Glycan array screening revealms the sialic acid binding specificity of M-ficolin.
Journal of Biological Chemistry (2010) 285(9) : 6612-6622

Gout E, Gutkowska M, Takayama S, Reed JC and Chroboczek J
Co-chaperone BAG3 and adenovirus penton base protein partnership.
Journal of Cellular Biochemistry (2010) 111(3) : 699-708

Gout E, Schoehn G, Fenel D, Lortat-Jacob H and Fender P
The Adenovirus type 3 dodecahedron’s RGD loop comprises a HSPG binding site that influences integrin binding.
Journal of Biomedicine and Biotechnology (2010) : 541939

Hair PS, Gronemus JQ, Crawford KB, Salvi VP, Cunnion KM, Thielens NM, Arlaud GJ, Rawal N and Krishna NK
Human astrovirus coat protein binds C1q and MBL and inhibits the classical and lectin pathways of complement activation.
Molecular Immunology (2010) 47(4) : 792-798

Pflieger D, Przybylski C, Gonnet F, Le Caer JP, Lunardi T, Arlaud GJ and R. D
Analysis of human C1q by combined bottom-up and top-down mass spectrometry : Detailed mapping of post-translational modifications and insights into the C1r/C1s binding sites.
Molecular and Cellular Proteomics (2010) 9(4) : 593-610

Prudent R, Moucadel V, Nguyen CH, Barette C, Schmidt F, Florent JC, Lafanechere L, Sautel CF, Duchemin-Pelletier E, Spreux E, Filhol O, Reiser JB and Cochet C
Antitumor activity of pyridocarbazole and benzopyridoindole derivatives that inhibit protein kinase CK2.
Cancer Research (2010) 70 (23) : 9865-9874

Rossi V, Bally I, Ancelet S, Xu Y, Fremeaux-Bacchi V, Vives RR, Sadir R, Thielens N and Arlaud GJ
Functional characterization of the recombinant human C1 inhibitor serpin domain : insights into heparin binding.
Journal of Immunology (2010) 184(9) : 4982-4989

Rossi V, Wang Y and Esser AF
Topology of the membrane-bound form of complement protein C9 probed by glycosylation mapping, anti-peptide antibody binding, and disulfide modification.
Molecular Immunology (2010) 47(7-8) : 1553-1560

Publications 2009

Andreoletti P, Mouesca J-M, Gouet P, Jaquinod M, Capeillère-Blandin C and Jouve HM
Verdoheme formation in Proteus mirabilis catalase.
Biochimica et Biophysica Acta (BBA) - General Subjects (2009) 1790(8) : 741-753

Bally I, Rossi V, Lunardi T, Thielens NM, Gaboriaud C and Arlaud GJ
Identification of the C1q-binding Sites of Human C1r and C1s : a refined three-dimensional model of the C1 complex of complement.
Journal of Biological Chemistry (2009) 284(29) : 19340-19348

Biro A and Arlaud GJ
C1 activation by enzymatically modified low-density lipoprotein involves free lipids released by cholesterol esterase treatment.
Molecular Immunology (2009) 46(14) : 2845-2845

Erlich P, Dumestre-Pérard C, Ling WL, Lemaire-Vieille C, Arlaud G, Gagnon J and Cesbron J-Y
Prion protein oligomers and C1q recognition.
Molecular Immunology (2009) 46(14) : 2837-2837

Gout E, Garlatti V, Smith D, Lacroix M, Lunardi T, Arlaud GJ, Gaboriaud C and Thielens NM
Carbohydrate recognition properties of human ficolins : Glycan array screening provides insights into the sialic acid binding specificity of M-ficolin.
Molecular Immunology (2009) 46(14) : 2819-2819

Gras S, Saulquin X, Reiser J-B, Debeaupuis E, Echasserieau K, Kissenpfennig A, Legoux F, Chouquet A, Le Gorrec M, Machillot P, Neveu B, Thielens N, Malissen B, Bonneville M and Housset D
Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope.
Journal of Immunology (2009) 183(1) : 430-437

Lacroix M, Dumestre-Perard C, Schoehn G, Houen G, Cesbron JY, Arlaud GJ and Thielens NM
Residue Lys57 in the collagen-like region of human L-ficolin and its counterpart Lys47 in H-ficolin play a key role in the interaction with the mannan-binding lectin-associated serine proteases and the collectin receptor calreticulin.
Journal of Immunology (2009) 182(1) : 456-465

Ma YJ, Doni A, Hummelshoj T, Honore C, Bastone A, Mantovani A, Thielens NM and Garred P
Synergy between ficolin-2 and PTX3 boost innate immune recognition and complement deposition.
Journal of Biological Chemistry (2009) 284(41) : 28263-28275

Païdassi H, Tacnet-Delorme P, Arlaud GJ and Frachet P
How phagocytes track down and respond to apoptotic cells.
Critical Reviews in Immunology (2009) 29(2) : 111-130

Reiser JB, Legoux F, Machillot P, Debeaupuis E, Le Moullac-Vaydie B, Chouquet A, Saulquin X, Bonneville M and Housset D
Crystallization and preliminary X-ray crystallographic characterization of a public CMV specific TCR in complex with its cognate antigen.
Acta Crystallographica Section F-Structural Biology and Crystallization Communications (2009) 65(11) : 1157-1161

Rossi V, Bally I, Xu Y, Frémeaux-Bacchi V, Vives R, Ancelet S and Arlaud GJ
Expression and functional characterization of the serpin domain of human C1 inhibitor.
Molecular Immunology (2009) 46(14) : 2863-2863

Spierings E, Gras S, Reiser JB, Mommaas B, Almekinders M, Kester MGD, Chouquet A, Le Gorrec M, Drijfhout JW, Ossendorp F, Housset D and Goulmy E
Steric hindrance and fast dissociation explain the lack of immunogenicity of the minor histocompatibility HA-1Arg null allele.
Journal of Immunology (2009) 182(8) : 4809-4816

Publications 2008

Bally I, Rossi V, Thielens N, Gaboriaud C and Arlaud G
Identification of the C1q binding sites of C1r and C1s : A refined 3D model of the C1 complex.
Molecular Immunology (2008) 45(16) : 4097-4097

Biro A and Arlaud GJ
C1q recognizes the lipid component of enzymatically modified low-density lipoprotein.
Molecular Immunology (2008) 45(16) : 4140-4140

Crublet E, Andrieu JP, Vives RR and Lortat-Jacob H
The HIV-1 envelope glycoprotein gp120 features four heparan sulfate binding domains, including the co-receptor binding site.
Journal of Biological Chemistry (2008) 283(22) : 15193-15200

de Rosny E, de Groot A, Jullian-Binard C, Borel F, Suarez C, Le Pape L, Fontecilla-Camps JC and Jouve HM
DHR51, the Drosophila melanogaster homologue of the human photoreceptor cell-specific nuclear receptor, is a thiolate heme-binding protein.
Biochemistry (2008) 47(50) : 13252-13260

Erlich P, Cesbron JY, Lemaire-Vieille C, Curt A, Andrieu JP, Schoehn G, Jamin M and Gagnon J
PrP N-terminal domain triggers PrPSc-like aggregation of Dpl.
Biochemical and Biophysical Research Communications (2008) 365(3) : 478-483

Kerr FK, Thomas AR, Wijeyewickrema LC, Whisstock JC, Boyd SE, Kaiserman D, Matthews AY, Bird PI, Thielens NM, Rossi V and Pike RN
Elucidation of the substrate specificity of the MASP-2 protease of the lectin complement pathway and identification of the enzyme as a major physiological target of the serpin, C1-inhibitor.
Molecular Immunology (2008) 45(3) : 670-677

Lacroix M, Dumestre-Pérard C, Houen G, Arlaud G and Thielens N
Residue Lys57 in the collagen-like region of human l-ficolin and its counterpart Lys47 in H-ficolin play an essential role in interaction with the MASPs and the collectin co-receptor calreticulin.
Molecular Immunology (2008) 45(16) : 4134-4134

Ma YJ, Doni A, Honoré C, Mantovani A, Thielens NM and Garred P
Biochemical and functional characterisation of the interaction between pentraxin 3 and the ficolins.
Molecular Immunology (2008) 45(16) : 4135-4135

Pagh R, Duus K, Laursen I, Hansen PR, Mangor J, Thielens N, Arlaud GJ, Kongerslev L, Hojrup P and Houen G
The chaperone and potential mannan-binding lectin (MBL) co-receptor calreticulin interacts with MBL through the binding site for MBL-associated serine proteases.
FEBS Journal (2008) 275(3) : 515-526

Paidassi H, Tacnet-Delorme P, Garlatti V, Darnault C, Ghebrehiwet B, Gaboriaud C, Arlaud GJ and Frachet P
C1q binds phosphatidylserine and likely acts as a multiligand-bridging molecule in apoptotic cell recognition.
Journal of Immunology (2008) 180(4) : 2329-2338

Païdassi H, Tacnet-Delorme P, Lunardi T, Arlaud GJ, Thielens NM and Frachet P
The lectin-like activity of human C1q and its implication in DNA and apoptotic cell recognition.
Febs Letters (2008) 582(20) : 3111-3116

Tacnet P, Cheong EC, Goeltz P, Ghebrehiwet B, Arlaud GJ, Liu XY and Lesieur C
Trimeric reassembly of the globular domain of human C1q.
Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics (2008) 1784(3) : 518-529

Teillet F, Gaboriaud C, Lacroix M, Martin L, Arlaud GJ and Thielens NM
Crystal structure of the CUB1-EGF-CUB2 domain of human MASP-1/3 and identification of its interaction sites with mannan-binding lectin and ficolins.
Journal of Biological Chemistry (2008) 283(37) : 25715-25724

Wijeyewickrema LC, Quinsey N, Thielens N, Boyd SE, Matthews AY, Kaiserman D, Bird PI and Pike RN
Determination of the substrate specificity of the MASP-1 protease of the complement pathway provides initial insights into potential physiological roles.
Molecular Immunology (2008) 45(16) : 4136-4136

Publications 2007

Arlaud GJ, Barlow PN, Gaboriaud C, Gros P and Narayana SVL
Deciphering complement mechanisms : The contributions of structural biology.
Molecular Immunology (2007) 44(16) : 3809-3822

Biro A, Rovo Z, Papp D, Cervenak L, Varga L, Fust G, Thielens NM, Arlaud GJ and Prohaszka Z
Studies on the interactions between C-reactive protein and complement proteins.
Immunology (2007) 121(1) : 40-50

Biro A, Thielens NM, Cervenak L, Prohaszka Z, Fust G and Arlaud GJ
Modified low density lipoproteins differentially bind and activate the C1 complex of complement.
Molecular Immunology (2007) 44(6) : 1169-1177

Boudet J, Chouquet A, Chahboune A, Giustini C, Joris B, Simorre JP and Bougault CM
1H, 13C and 15N resonance assignments of YajG, an Escherichia coli protein of unknown structure and function.
Biomolecular NMR Assignments (2007) 1 : 89-91

Csomor E, Bajtay Z, Sandor N, Kristof K, Arlaud GJ, Thiel S and Erdei A
Complement protein C1q induces maturation of human dendritic cells.
Molecular Immunology (2007) 44(13) : 3389-3397

Dumestre-Perard C, Osmundson J, Lemaire-Vieille C, Thielens N, Grives A, Favier B, Csopaki F, Jamin M, Gagnon J and Cesbron JY
Activation of classical pathway of complement cascade by soluble oligomers of prion.
Cellular Microbiology (2007) 9(12) : 2870-2879

Dycke C, Bougault C, Gaillard J, Andrieu JP, Pantopoulos K and Moulis JM
Human iron regulatory protein 2 is easily cleaved in its specific domain : consequences for the haem binding properties of the protein.
Biochemical Journal (2007) 408(3) : 429-439

Gaboriaud C, Teillet F, Gregory LA, Thielens NM and Arlaud GJ
Assembly of C1 and the MBL- and ficolin-MASP complexes : Structural insights.
Immunobiology (2007) 212(4-5) : 279-288

Garlatti V, Belloy N, Martin L, Lacroix M, Matsushita M, Endo Y, Fujita T, Fontecilla-Camps JC, Arlaud GJ, Thielens NM and Gaboriaud C
Structural insights into the innate immune recognition specificities of L- and H-ficolins.
Embo Journal (2007) 26(2) : 623-633

Garlatti V, Belloy N, Martin L, Lacroix M, Matsushita M, Fujita T, Fontecilla-Camps JC, Arlaud GJ, Thielens NM and Gaboriaud C
The crystal structures of the binding domains of L- and H-ficolins provide insight into their recognition versatility.
Molecular Immunology (2007) 44(1-3) : 175-175

Garlatti V, Martin L, Gout E, Reiser JB, Fujita T, Arlaud GJ, Thielens NM and Gaboriaud C
Structural basis for innate immune sensing by M-ficolin and its control by a pH-dependent conformational switch.
Journal of Biological Chemistry (2007) 282(49) : 35814-35820

Garlatti V, Martin L, Gout E, Reiser JB, Fujita T, Arlaud GJ, Thielens NM and Gaboriaud C
Innate immune sensing : Ligand recognition by M-ficolin is subject to a pH-dependent conformational switch.
Molecular Immunology (2007) 44(16) : 3928-3929

Gras S, Chaumont V, Fernandez B, Carpentier P, Charrier-Savournin F, Schmitt S, Pineau C, Flament D, Hecker A, Forterre P, Armengaud J and Housset D
Structural insights into a new homodimeric self-activated GTPase family.
EMBO Reports (2007) 8(6) : 569-575

Hummelshoj T, Thielens NM, Madsen HO, Arlaud GJ, Sim RB and Garred P
Molecular organization of human Ficolin-2.
Molecular Immunology (2007) 44(4) : 401-411

Martelli A, Salin B, Dycke C, Louwagie M, Andrieu JP, Richaud P and Moulis JM
Folding and turnover of human iron regulatory protein 1 depend on its subcellular localization.
FEBS Journal (2007) 274(4) : 1083-1092

Morlot C, Thielens NM, Ravelli RB, Hemrika W, Romijn RA, Gros P, Cusack S and McCarthy AA
Structural insights into the Slit-Robo complex.
Proceedings of the National Academy of Sciences USA (2007) 104(38) : 14923-14928

Paidassi H, Tacnet-Delorme P, Garlatti V, Darnault C, Ghebrehiwet B, Gaboriaud C, Arlaud GJ and Frachet P
C1q binds phosphatidylserine and likely acts as an early bridging molecule in apoptotic cell recognition and clearance.
Molecular Immunology (2007) 44(1-3) : 225-226

Teillet F, Gaboriaud C, Martin L, Lacroix M, Ogbi S, Fontecilla-Camps JC, Arlaud GJ and Thielens NM
The CUB1-EGF-CUB2 interaction domain of human MBL-associated serine protease-3 : X-ray structure and binding sites for MBL and ficolins.
Molecular Immunology (2007) 44(1-3) : 249

Teillet F, Lacroix M, Thiel S, Weilguny D, Agger T, Arlaud GJ and Thielens NM
Identification of the site of human mannan-binding lectin involved in the interaction with its partner serine proteases : the essential role of lys55.
Journal of Immunology (2007) 178(9) : 5710-5716

Publications 2006

de Rosny E, de Groot A, Jullian-Binard C, Gaillard J, Borel F, Pebay-Peyroula E, Fontecilla-Camps JC and Jouve HM
Drosophila nuclear receptor E75 is a thiolate hemoprotein.
Biochemistry (2006) 45(32) : 9727-9734

Garcel A, Gout E, Timmins J, Chroboczek J and Fender P
Protein transduction into human cells by adenovirus dodecahedron using WW domains as universal adaptors.
Journal of Gene Medicine (2006) 8(4) : 524-531

Horner O, Oddou JL, Mouesca JM and Jouve HM
Mossbauer identification of a protonated ferryl species in catalase from Proteus mirabilis : Density functional calculations on related models.
Journal of Inorganic Biochemistry (2006) 100(4) : 477-479

McGrath FD, Brouwer MC, Arlaud GJ, Daha MR, Hack CE and Roos A
Evidence that complement protein C1q interacts with C-reactive protein through its globular head region.
Journal of Immunology (2006) 176(5) : 2950-2957

Renault F, Chabriere E, Andrieu J-P, Dublet B, Masson P and Rochu D
Tandem purification of two HDL-associated partner proteins in human plasma, paraoxonase (PON1) and phosphate binding protein (HPBP) using hydroxyapatite chromatography.
_ Journal of Chromatography B Analytical Technologies in the Biomedical Life Science (2006) 836(1-2) : 15-21

Van den Brandt B, Glattli H, Grillo I, Hautle P, Jouve H, Kohlbrecher J, Konter JA, Leymarie E, Mango S, May R, Michels A, Stuhrmann H and Zimmer O
Time-resolved nuclear spin-dependent small-angle neutron scattering from polarised proton domains in deuterated solutions.
European Physical Journal B (2006) 49 : 157-165

Publications 2005

Arlaud GJ, Gaboriaud C, Thielens NM, Gregory LA, Juanhuix J, Rossi V and Fontecilla-Camps JC
The classical pathway C1 complex in Structural biology of the complement system, édité par Lambris J D and Morikis D, CRC Press (2005) pp 63-90

Bally I, Rossi V, Thielens N, Gaboriaud C and Arlaud GJ
Functional role of the linker between the complement control protein modules of complement protease C1s.
Journal of Immunology (2005) 175(7) : 4536-4542

Blanquet-Grossard F, Thielens NM, Vendrely C, Jamin M and Arlaud GJ
Complement protein C1q recognizes a conformationally modified form of the prion protein.
Biochemistry (2005) 44(11) : 4349-4356

Dura MA, Receveur-Brechot V, Andrieu JP, Ebel C, Schoehn G, Roussel A and Franzetti B
Characterization of a TET-like aminopeptidase complex from the hyperthermophilic archaeon Pyrococcus horikoshii.
Biochemistry (2005) 44(9) : 3477-3486

Gras S, Fernandez B, Chaumont V, Carpentier P, Armengaud J and Housset D
Expression, purification, crystallization and preliminary
crystallographic analysis of the PAB0955 gene product.
Acta Crystallographica Section F Structural Biology and Crystallization Communications (2005) 61(Part 2) : 208-211

Groeneveld TW, Oroszlan M, Owens RT, Faber-Krol MC, Bakker AC, Arlaud GJ, McQuillan DJ, Kishore U, Daha MR and Roos A
Interactions of the extracellular matrix proteoglycans decorin and biglycan with C1q and collectins.
Journal of Immunology (2005) 175(7) : 4715-4723

Mitraki A and van Raaij MJ
Folding of beta-structured fibrous proteins and self-assembling peptides.
Methods in Molecular Biology (Clifton, N.J.) (2005) 300 : 125-140

Papanikolopoulou K, Schoehn G, Forge V, Forsyth VT, Riekel C, Hernandez JF, Ruigrok RW and Mitraki A
Amyloid fibril formation from sequences of a natural beta-structured fibrous protein, the adenovirus fiber.
Journal of Biological Chemistry (2005) 280(4) : 2481 - 2490

Rossi V, Teillet F, Thielens NM, Bally I and Arlaud GJ
Functional characterization of complement proteases C1s/mannan-binding lectin-associated serine protease-2 (MASP-2) chimeras reveals the higher C4 recognition efficacy of the MASP-2 complement control protein modules.
Journal of Biological Chemistry (2005) 280(51) : 41811-41818

Teillet F, Dublet B, Andrieu JP, Gaboriaud C, Arlaud GJ and Thielens NM
The two major oligomeric forms of human mannan-binding lectin : chemical characterization, carbohydrate-binding properties, and interaction with MBL-associated serine proteases.
Journal of Immunology (2005) 174(5) : 2870-2877

Tissot B, Gonnet F, Iborra A, Berthou C, Thielens N, Arlaud GJ and Daniel R
Mass spectrometry analysis of the oligomeric C1q protein reveals the B chain as the target of trypsin cleavage and interaction with fucoidan.
Biochemistry (2005) 44(7) : 2602-2609

Publications 2004

Andreoletti P, Pernoud A, Sainz G, Gouet P and Jouve HM
Structural studies of Proteus mirabilis catalase in its ground state, oxidized state and in complex with formic acid (vol D59, pg 2163, 2003).
Acta Crystallographica D Biological Crystallography (2004) 60(Part 3) : 617

Gaboriaud C, Thielens NM, Gregory LA, Rossi V, Fontecilla-Camps JC and Arlaud GJ
Structure and activation of the C1 complex of complement : unraveling the puzzle.
Trends in Immunology (2004) 25(7) : 368-373

Gregory L, Thielens N, Matsushita M, Sorensen R, Arlaud G, Fontecilla-Camps J and Gaboriaud C
The X-ray structure of human mannan-binding lectin-associated protein 19 (MAp19) and its interaction site with mannan-binding lectin and L-ficolin.
Journal of Biological Chemistry (2004) 279(28) : 29391 - 29397

Housset D and Malissen B
Response to Cohn : What determines the overall geometry of TCR-peptide-MHC interactions ?
Trends In Immunology (2004) 25(1) : 9-10

Kishore U, Gaboriaud C, Waters P, Shrive AK, Greenhough TJ, Reid KBM, Sim RB and Arlaud GJ
C1q and tumor necrosis factor superfamily : modularity and versatility.
Trends in Immunology (2004) 25(10) : 551-561

Papanikolopoulou K, Forge V, Goeltz P and Mitraki A
Formation of highly stable chimeric trimers by fusion of an adenovirus fiber shaft fragment with the foldon domain of bacteriophage t4 fibritin.
Journal of Biological Chemistry (2004) 279(10) : 8991-8998

Papanikolopoulou K, Teixeira S, Belrhali H, Forsyth VT, Mitraki A and Van Raaij MJ
Adenovirus fibre shaft sequences fold into the native triple beta-spiral fold when N-terminally fused to the bacteriophage T4 fibritin foldon trimerisation motif.
Journal of Molecular Biology (2004) 342(1) : 219-227

Thielens N and Arlaud GJ
L’immunité innée, première ligne de défense contre l’infection.
Réalités pédiatriques (2004) 92 : 17-22

van den Brandt B, Glattli H, Grillo I, Hautle P, Jouve H, Kohlbrecher J, Konter JA, Leymarie E, Mango S and May R
An experimental approach to the dynamics of nuclear polarisation.
Nuclear Instruments and Methods in Physics Research Section A : Accelerators, Spectrometers, Detectors and Associated Equipment (2004) 526(1-2) : 81-90

van Raaij MJ and Mitraki A
Beta-structured viral fibres : assembly, structure and implications for materials design.
Current Opinion in Solid State and Materials Science (2004) 8(2) : 151-156

Zundel S, Cseh S, Lacroix M, Dahl MR, Matsushita M, Andrieu JP, Schwaeble WJ, Jensenius JC, Fujita T, Arlaud GJ and Thielens NM
Characterization of recombinant mannan-binding lectin-associated serine protease (MASP)-3 suggests an activation mechanism different from that of MASP-1 and MASP-2.
Journal of Immunology (2004) 172(7) : 4342-4350

Publications 2003

Andreoletti P, Pernoud A, Sainz G, Gouet P and Jouve H M
Structural studies of Proteus mirabilis catalase in its ground state, oxidized state and in complex with formic acid
Acta Crystallographica D Biological Crystallography (2003) 59(Pt 12) : 2163-8

Andreoletti P, Sainz G, Jaquinod M, Gagnon J and Jouve H M
High-resolution structure and biochemical properties of a recombinant Proteus mirabilis catalase depleted in iron
Proteins (2003) 50(2) : 261-71

Arlaud GJ, Rossi V and Gaboriaud C
Complement component C1s in Handbook of proteolytic enzymes, 2nd edition (2003) vol. 2, édité par Barrett A J, Rawlings N D and Woessner J F Academic Press pp. 1620-1622

Arlaud GJ, Thielens N and Gaboriaud C
Complement component C1r in Handbook of proteolytic enzymes, 2nd edition (2003) vol. 2, édité par Barrett A J, Rawlings N D and Woessner J F Academic Press pp. 1617-1620

Bouvier D, Vanhaverbeke C, Simorre J P, Arlaud G J, Bally I, Forge V, Margolis R L, Gans P and Kleman J P
Unusual Ca2+-calmodulin binding interactions of the microtubule-associated protein F-STOP
Biochemistry (2003) 42(39) : 11484-11493

Brandt B v d, Glattli H, Grillo I, Hautle P, Jouve H, Kohlbrecher J, Konter J A, Leymarie E, Mango S and May R P
Neutron scattering from polarised proton domains
Physica B : Condensed Matter (2003) 335(1-4) : 193-195

Gaboriaud C, Juanhuix J, Gruez A, Lacroix M, Darnault C, Pignol D, Verger D, Fontecilla Camps J C and Arlaud G J
The crystal structure of the globular head of complement protein C1q provides a basis for its versatile recognition properties
Journal of Biological Chemistry (2003) 278(47) : 46974-82

Gregory L A, Thielens N M, Arlaud G J, Fontecilla-Camps J C and Gaboriaud C
X-ray Structure of the Ca2+-binding Interaction Domain of C1s : Insights into the assembly of the C1 complex of complement
The Journal Of Biological Chemistry (2003) 278(34) : 32157-32164

Housset D and Malissen B
What do TCR-pMHC crystal structures teach us about MHC restriction and alloreactivity ?
Trends In Immunology (2003) 24(8) : 429-437

Moller-Kristensen M, Jensenius J C, Jensen L, Thielens N, Rossi V, Arlaud G and Thiel S
Levels of mannan-binding lectin-associated serine protease-2 in healthy individuals
Journal of Immunological Methods (2003) 282(1-2 SU -) : 159-167

Reiser J B, Darnault C, Gregoire C, Mosser T, Mazza G, Kearney A, van der Merwe P A, Fontecilla-Camps J C, Housset D and Malissen B
CDR3 loop flexibility contributes to the degeneracy of TCR recognition.
Nature Immunology (2003) 4(3) : 241-7

Varga L, Szilagyi K, Lorincz Z, Berrens L, Thiel S, Zavodszky P, Daha M, Thielens N, Arlaud G and Nagy K
Studies on the mechanisms of allergen-induced activation of the classical and lectin pathways of complement
Molecular Immunology (2003) 39(14) : 839-346

Vella F, Thielens N M, Bersch B, Arlaud G J and Frachet P
A recombinant chimeric epidermal growth factor-like module with high binding affinity for integrins
The Journal Of Biological Chemistry (2003) 278(22) : 19834-19843

Publications 2002

Arlaud GJ, Gaboriaud C, Garnier G, Circolo A, Thielens NM, Budayova-Spano M, Fontecilla-Camps JC and Volanakis JE
Structure, function and molecular genetics of human and murine C1r
Immunobiology (2002) 205(4-5) : 365-382

Arlaud G J, Gaboriaud C, Thielens N M and Rossi V
Structural biology of the C1.
Biochemical Society Transaction (2002) 30(6) : 1001-1006

Arlaud GJ, Gaboriaud C, Thielens NM, Budayova-Spano M, Rossi V and Fontecilla-Camps JC
Structural biology of the C1 complex of complement unveils the mechanisms of its activation and proteolytic activity
Molecular Immunology (2002) 39(7-8) : 383-394

Budayova-Spano M, Grabarse W, Thielens NM, Hillen H, Lacroix M, Schmidt M, Fontecilla-Camps JC, Arlaud GJ and Gaboriaud C
Monomeric structures of the zymogen and active catalytic domain of complement protease c1r. Further insights into the c1 activation mechanism
Structure (Camb) (2002) 10(11) : 1509-19

Budayova-Spano M, Lacroix M, Thielens NM, Arlaud GJ, Fontecilla-Camps JC and Gaboriaud C
The crystal structure of the zymogen catalytic domain of complement protease C1r reveals that a disruptive mechanical stress is required to trigger activation of the C1 complex
Embo Journal (2002) 21(3) : 231-9

Buisson M, Hernandez JF, Lascoux D, Schoehn G, Forest E, Arlaud G, Seigneurin JM, Ruigrok RW and Burmeister WP
The crystal structure of the epstein-barr virus protease shows rearrangement of the processed C terminus
Journal of Molecular Biology (2002) 324(1) : 89-103

Cseh S, Vera L, Matsushita M, Fujita T, Arlaud GJ and Thielens NM
Characterization of the interaction between L-ficolin/p35 and mannan- binding lectin-associated serine proteases-1 and -2
Journal of Immunology (2002) 169(10) : 5735-43

Dumestre-Perard C, Ponard D, Arlaud G J, Monnier N, Sim R B and Colomb M G
Evaluation and clinical interest of mannan binding lectin function in human plasma.
Molecular Immunology (2002) 39(7-8) : 465-73

Mitraki A, Miller S and van Raaij M J
Review : conformation and folding of novel Beta-structural elements in viral fiber proteins : the triple Beta-spiral and triple Beta-helix.
Journal of Structural Biology (2002) 137(1-2) : 236-47

Reiser JB, Gregoire C, Darnault C, Mosser T, Guimezanes A, Schmitt-Verhulst AM, Fontecilla-Camps JC, Mazza G, Malissen B and Housset D
A T cell receptor CDR3beta loop undergoes conformational changes of unprecedented magnitude upon binding to a peptide/MHC class I complex
Immunity (2002) 16(3) : 345-54

Thielens NM, Tacnet-Delorme P and Arlaud GJ
Interaction of C1q and mannan-binding lectin with viruses
Immunobiology (2002) 205(4-5) : 563-574

van den Brnadt B, Glattli H, Grillo I, Hautle P, Jouve H, Kohlbrecher J, Konter J A, Leymarie E, Mango S, May R P, Stuhrmann H P and Zimmer O
Neutron scattering from polarised proton domains.
Europhysics Letters (2002) 59(1) : 62-67

Publications 2001

Amara, P., Andreoletti, P., Jouve, H. M. and Field, M. J.
Ligand diffusion in the catalase from Proteus mirabilis : A molecular dynamics study.
Protein Science (2001) 10(10) : 1927-1935

Andreoletti P, Franzetti B, Nussaume L, Andrieu JP, Gagnon J, Luche S, Rabilloud T and Jouve H
Comparison of the PR mutant with the wild-type strain of Proteus mirabilis brings insight into peroxide resistance factors and regulation of catalase expression
Canadian Journal of Microbiology (2001) 47(2) : 130-138

Andreoletti P, Gambarelli S, Sainz G, Stojanoff V, White C, Desfonds G, Gagnon J, Gaillard J and Jouve HM
Formation of a tyrosyl radical intermediate in Proteus mirabilis catalase by directed mutagenesis and consequences for nucleotide reactivity
Biochemistry (2001) 40(45) : 13734-43

Arlaud, G. J., Gaboriaud, C., Thielens, N. M., Rossi, V., Bersch, B., Hernandez, J. F. and Fontecilla Camps, J. C.
Structural biology of C1 : dissection of a complex molecular machinery.
Immunological Reviews (2001) 180 : 136-145

Buisson, M., Valette, E., Hernandez, J. F., Baudin, F., Ebel, C., Morand, P., Seigneurin, J. M., Arlaud, G. J. and Ruigrok, R. W.
Functional determinants of the Epstein-Barr virus protease.
Journal of Molecular Biology (2001) 311(1) : 217-28

Durmort C, Stehlin C, Schoehn G, Mitraki A, Drouet E, Cusack S and Burmeister WP
Structure of the fiber head of Ad3, a non-CAR-binding serotype of adenovirus
Virology (2001) 285(2) : 302-12

Franzetti, B., Schoehn, G., Ebel, C., Gagnon, J., Ruigrok, R. W. and Zaccai, G.
Characterization of a novel complex from halophilic archaebacteria, which displays chaperone-like activities in vitro.
Journal of Biological Chemistry (2001) 276(32) : 29906-14

Grizot S, Grandvaux N, Fieschi F, Faure J, Massenet C, Andrieu JP, Fuchs A, Vignais PV, Timmins PA, Dagher MC and Pebay Peyroula E
Small angle neutron scattering and gel filtration analyses of neutrophil NADPH oxidase cytosolic factors highlight the role of the C-terminal end of p47(phox) in the association with p40(phox)
Biochemistry (2001) 40(10) : 3127-3133

Heitz, A., Hernandez, J. F., Gagnon, J., Hong, T. T., Pham, T. T. C., Nguyen, T. M., Le Nguyen, D. and Chiche, L.
Solution structure of the squash trypsin inhibitor MCoTI-II. A new family for cyclic knottins.
Biochemistry (2001) 40(27) : 7973-7983

Kardos J, Gal P, Szilagyi L, Thielens NM, Szilagyi K, Lorincz Z, Kulcsar P, Graf L, Arlaud GJ and Zavodszky P
The role of the individual domains in the structure and function of the catalytic region of a modular serine protease, C1r
Journal of Immunology (2001) 167(9) : 5202-8

Lacroix, M., Ebel, C., Kardos, J., Dobo, J., Gal, P., Zavodszky, P., Arlaud, G. J. and Thielens, N. M.
Assembly and enzymatic properties of the catalytic domain of human complement protease C1r
Journal of Biological Chemistry (2001) 276(39) : 36233-40

Rossi, V., Cseh, S., Bally, I., Thielens, N. M., Jensenius, J. C. and Arlaud, G. J.
Substrate specificities of recombinant mannan-binding lectin-associated serine proteases-1 and-2.
Journal of Biological Chemistry
(2001) 29 : 29

Tacnet-Delorme P, Chevallier S and Arlaud GJ
beta-Amyloid Fibrils Activate the C1 Complex of Complement Under Physiological Conditions : Evidence for a Binding Site for Abeta on the C1q Globular Regions
Journal of Immunology (2001) 167(11) : 6374-81

Tetaert D, Richet C, Gagnon J, Boersma A and Degand P
Studies of acceptor site specificities for three members of UDP- GalNAc:N-acetylgalactosaminyltransferases by using a synthetic peptide mimicking the tandem repeat of MUC5AC
Carbohydrate Research (2001) 333(2) : 165-71

Tetaert D, Ten Hagen KG, Richet C, Boersma A, Gagnon J and Degand P
Glycopeptide N-acetylgalactosaminyltransferase specificities for O- glycosylated sites on MUC5AC mucin motif peptides
Biochemical Journal (2001) 357(Pt 1) : 313-20

Thielens, N. M., Cseh, S., Thiel, S., Vorup-Jensen, T., Rossi, V., Jensenius, J. C. and Arlaud, G. J.
Interaction properties of human mannan-binding lectin (MBL)-associated serine proteases-1 and -2, MBL-associated protein 19, and MBL.
Journal of Immunology (2001) 166(8) : 5068-77

Publications 2000

Aude-Garcia, C., Attinger, A., Housset, D., MacDonald, H. R., Acha-Orbea, H., Marche, P. N. and Jouvin-Marche, E.
Pairing of Vbeta6 with certain Valpha2 family members prevents T cell deletion by Mtv-7 superantigen.
Molecular Immunology (2000) 37(16) : 1005-12

Bajtay, Z., Jozsi, M., Banki, Z., Thiel, S., Thielens, N. and Erdei, A.
Mannan-binding lectin and C1q bind to distinct structures and exert differential effects on macrophages.
European Journal of Immunology (2000) 30(6) : 1706-13

Hernandez, J. F., J. Gagnon, L. Chiche, T. M. Nguyen, J. P. Andrieu, A. Heitz, T. Trinh Hong, T. T. Pham and D. Le Nguyen
Squash trypsin inhibitors from Momordica cochinchinensis exhibit an atypical macrocyclic structure.
Biochemistry (2000) 39(19) : 5722-5730

Gaboriaud, C., Rossi, V., Bally, I., Arlaud, G. J. and Fontecilla-Camps, J. C.
Crystal structure of the catalytic domain of human complement c1s : a serine protease with a handle.
Embo Journal (2000) 19(8) : 1755-65

Housset, D., F. Benabicha, V. Pichon-Pesme, C. Jelsch, A. Maierhofer, S. David, J. Fontecilla-Camps and C. Lecomte
Towards the charge-density study of proteins : a room-temperature scorpion-toxin structure at 0.96 A resolution as a first test case.
Acta Crystallographica D Biological Crystallography (2000) 56(2) : 151-160

Luckey, M., J. Hernandez, G. Arlaud, V. T. Forsyth, R. W. Ruigrok and A. Mitraki
A peptide from the adenovirus fiber shaft forms amyloid-type fibrils
FEBS Letters (2000) 468(1) : 23-7

Morales, R., M. H. Charon, G. Hudry-Clergeon, Y. Petillot, S. Norager, M. Medina and M. Frey
Refined X-ray Structures of the Oxidized, at 1.3 A, and Reduced, at 1.17 A, [2Fe-2S] Ferredoxin from the Cyanobacterium Anabaena PCC7119 Show Redox-Linked Conformational Changes.
Biochemistry (2000) 39(9) : 2428

Reiser, JB, Darnault, C, Guimezanes, A, Gregoire, C., Mosser, T, Schmitt-Verhulst, AM, Fontecilla Camps, J.C., Malissen, B., Housset, D and Mazza, G.
Crystal structure of the T cell receptor bound to an allogeneic MHC molecule.
Nature Immunology (2000) 1(4) : 291-297

Zatylny, C., Gagnon, J., Boucaud-Camou, E. and Henry, J.
ILME : a waterborne pheromonal peptide released by the eggs of Sepia officinalis.
Biochemical & Biophysical Research Communications (2000) 275(1) : 217-22

Zatylny, C., Gagnon, J., Boucaud-Camou, E. and Henry, J.
The SepOvotropin : A new ovarian peptide regulating oocyte transport in sepia officinalis
Biochemistry & Biophysical Research Communications (2000) 276(3) : 1013-8