Institut de Biologie StructuraleGrenoble / France

Contacts relatifs à cet article / Grossi Laurence

Equipe Poignard


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30. Hessell, A. J., E. G. Rakasz, D. M. Tehrani, M. Huber, K. L. Weisgrau, G. Landucci, D. N. Forthal, W. C. Koff, P. Poignard, D. I. Watkins and D. R. Burton (2010). "Broadly neutralizing monoclonal antibodies 2F5 and 4E10 directed against the human immunodeficiency virus type 1 gp41 membrane-proximal external region protect against mucosal challenge by simian-human immunodeficiency virus SHIVBa-L." J Virol 84(3) : 1302-1313.
31. Pejchal, R., L. M. Walker, R. L. Stanfield, S. K. Phogat, W. C. Koff, P. Poignard, D. R. Burton and I. A. Wilson (2010). "Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1." Proc Natl Acad Sci U S A 107(25) : 11483-11488.
32. Walker, L. M., M. D. Simek, F. Priddy, J. S. Gach, D. Wagner, M. B. Zwick, S. K. Phogat, P. Poignard and D. R. Burton (2010). "A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals." PLoS Pathog 6(8) : e1001028.
33. Burton, D. R., A. J. Hessell, B. F. Keele, P. J. Klasse, T. A. Ketas, B. Moldt, D. C. Dunlop, P. Poignard, L. A. Doyle, L. Cavacini, R. S. Veazey and J. P. Moore (2011). "Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody." Proc Natl Acad Sci U S A 108(27) : 11181-11186.
34. Chakrabarti, B. K., L. M. Walker, J. F. Guenaga, A. Ghobbeh, P. Poignard, D. R. Burton and R. T. Wyatt (2011). "Direct antibody access to the HIV-1 membrane-proximal external region positively correlates with neutralization sensitivity." J Virol 85(16) : 8217-8226.
35. Moldt, B., N. Schultz, D. C. Dunlop, M. D. Alpert, J. D. Harvey, D. T. Evans, P. Poignard, A. J. Hessell and D. R. Burton (2011). "A panel of IgG1 b12 variants with selectively diminished or enhanced affinity for Fcgamma receptors to define the role of effector functions in protection against HIV." J Virol 85(20) : 10572-10581.
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42. Klein, F., C. Gaebler, H. Mouquet, D. N. Sather, C. Lehmann, J. F. Scheid, Z. Kraft, Y. Liu, J. Pietzsch, A. Hurley, P. Poignard, T. Feizi, L. Morris, B. D. Walker, G. Fatkenheuer, M. S. Seaman, L. Stamatatos and M. C. Nussenzweig (2012). "Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein." J Exp Med 209(8) : 1469-1479.
43. Moldt, B., E. G. Rakasz, N. Schultz, P. Y. Chan-Hui, K. Swiderek, K. L. Weisgrau, S. M. Piaskowski, Z. Bergman, D. I. Watkins, P. Poignard and D. R. Burton (2012). "Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo." Proc Natl Acad Sci U S A 109(46) : 18921-18925.
44. Moldt, B., M. Shibata-Koyama, E. G. Rakasz, N. Schultz, Y. Kanda, D. C. Dunlop, S. L. Finstad, C. Jin, G. Landucci, M. D. Alpert, A. S. Dugast, P. W. Parren, F. Nimmerjahn, D. T. Evans, G. Alter, D. N. Forthal, J. E. Schmitz, S. Iida, P. Poignard, D. I. Watkins, A. J. Hessell and D. R. Burton (2012). "A nonfucosylated variant of the anti-HIV-1 monoclonal antibody b12 has enhanced FcgammaRIIIa-mediated antiviral activity in vitro but does not improve protection against mucosal SHIV challenge in macaques." J Virol 86(11) : 6189-6196.
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48. Gach, J. S., H. Quendler, T. Tong, K. M. Narayan, S. X. Du, R. G. Whalen, J. M. Binley, D. N. Forthal, P. Poignard and M. B. Zwick (2013). "A human antibody to the CD4 binding site of gp120 capable of highly potent but sporadic cross clade neutralization of primary HIV-1." PLoS One 8(8) : e72054.
49. Hoffenberg, S., R. Powell, A. Carpov, D. Wagner, A. Wilson, S. Kosakovsky Pond, R. Lindsay, H. Arendt, J. Destefano, S. Phogat, P. Poignard, S. P. Fling, M. Simek, C. Labranche, D. Montefiori, T. Wrin, P. Phung, D. Burton, W. Koff, C. R. King, C. L. Parks and M. J. Caulfield (2013). "Identification of an HIV-1 clade A envelope that exhibits broad antigenicity and neutralization sensitivity and elicits antibodies targeting three distinct epitopes." J Virol 87(10) : 5372-5383.
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52. Lutje Hulsik, D., Y. Y. Liu, N. M. Strokappe, S. Battella, M. El Khattabi, L. E. McCoy, C. Sabin, A. Hinz, M. Hock, P. Macheboeuf, A. M. Bonvin, J. P. Langedijk, D. Davis, A. Forsman Quigley, M. M. Aasa-Chapman, M. S. Seaman, A. Ramos, P. Poignard, A. Favier, J. P. Simorre, R. A. Weiss, C. T. Verrips, W. Weissenhorn and L. Rutten (2013). "A gp41 MPER-specific llama VHH requires a hydrophobic CDR3 for neutralization but not for antigen recognition." PLoS Pathog 9(3) : e1003202.
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