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Institut de Biologie StructuraleGrenoble / France

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Presentation of the TEM platform

Introduction

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The EM platform provides three types of services
- Quality control (negative staining)
- Cryo-electron microscopy
- Cellular electron microscopy

The platform also provides access to equipments under certain conditions
Scientific collaborations, that require specific developments, are possible upon requests.

Key words

Negative staining, cryo-electron microscopy, tomography, cellular electron microscopy, correlative microscopy (CLEM).

Equipments

Transmission electron microscopes :

Instruments for cellular sample preparation :

  • Automated high-pressure freezer Leica HPM100
  • Automated freeze substitution machine Leica AFS2 + FSP
  • (Cryo-)ultra-microtome Leica UC7/FC7
  • Automated immuno-labeling machine Leica IGL

Valorisation

If you use EM platform results, please notify in your acknowledgements :

« This work used the platforms of the Grenoble Instruct-ERIC Center (ISBG : UMS 3518 CNRS-CEA-UGA-EMBL) with support from FRISBI (ANR-10 INSB-05-02) and GRAL (ANR-10-LABX-49-01) within the Grenoble Partnership for Structural Biology (PSB). The electron microscope facility is supported by the Rhône-Alpes Region, the Fondation Recherche Medicale (FRM), the fonds FEDER, the Centre National de la Recherche Scientifique (CNRS), the CEA, the University of Grenoble, EMBL, and the GIS-Infrastrutures
en Biologie Sante et Agronomie (IBISA). »

Access and costs

PSB members, academia and industry (see prices).

How to contact us ?

ibs-plateforme-em.contact@ibs.fr

Localization

IBS building, ground floor, group Methods and Electron Microscopy.

Quality

The platform is certified ISO9001-NFX 50-900.