Institut de Biologie StructuraleGrenoble / France

Publications since 2015

Our list of publications with peerReviewing, books and book sections since 2015 can be found here (data issued from HAL-IBS).

Publications until 2014

Publications 2014

Borel F, Hachi I, Palencia A, Gaillard M-C, Ferrer J-L
Crystal Structure of mouse Mu-crystallin complexed with NADPH and the T3 thyroid hormon
FEBS Journal (2014) 281: 1598-1612

Oksanen E, Blakeley MP, El-Hajji M, Ryde U, Budayova-Spano M
The Neutron Structure of Urate Oxidase Resolves a Long-Standing Mechanistic Conundrum and Reveals Unexpected Changes in Protonation
PloS One (2014) 9: e86651.

Schild F, Kieffer-Jaquinod S, Palencia A, Cobessi D, Sarret G, Zubieta C, Jourdain A, Dumas R, Forge V, Testemale D, Bourguignon J, Hugouvieux V.
Biochemical and biophysical characterization of the Selenium binding and reducing site in Arabidopsis thaliana homologue to mammals Selenium Binding Protein 1.
JBC 289(46): 31765-3176.

Publications 2013

Ferrer J-L, Larive NA, Bowler MW and Nurizzo D
Recent progress in robot-based systems for crystallography and their contribution to drug discovery.
Expert Opinion on Drug Discovery (2013) 7(8): 835-847

Heidari Khajepour MY, Lebrette H, Vernede X, Rogues P and Ferrer J-L
A geometrical approach for semi-automated crystal centering and in situ X-ray diffraction data collection.
Journal of Applied Crystallography (2013) 46: 740-745

Heidari Khajepour MY, Vernede X, Cobessi D, Lebrette H, Rogues P, Terrien M, Berzin C and Ferrer J-L
REACH: Robotic Equipment for Automated Crystal Harvesting using a six-axis robot arm and a micro-gripper.
Acta Crystallographica Section D-Biological Crystallography (2013) 69: 381-387

Publications 2012

Cobessi D, Dumas R, Pautre V, Meinguet C, Ferrer J-L and Alban C
Biochemical and structural characterization of the Arabidopsis bifunctional enzyme dethiobiotin synthetase-diaminopelargonic acid aminotransferase: Evidence for substrate channeling in biotin synthesis.
Plant Cell (2012) 24(4): 1608-1625

Dumas R, Cobessi D, Robin AY, Ferrer J-L and Curien G
The many faces of aspartate kinases.
Archives of Biochemistry and Biophysics (2012) 519(2): 186–193

Heidari Khajepour MY, Vernede X, Cobessi D, Lebrette H, Rogues P, Terrien M, Berzin C and Ferrer J-L
REACH: Robotic Equipment for Automated Crystal Harvesting, using a 6-axis robot arm and a micro-gripper.
Acta Crystallographica D Biological Crystallography (2012) 69(3): 381-387

Zhao N, Ferrer J-L, Moon HS, Kapteyn J, Zhuang X, Hasebe M, Neal Stewart Jr C, Gang DR and Chen F
A SABATH methyltransferase from the moss Physcomitrella patens catalyzes S-methylation of thiols and has a role in detoxification.
Phytochemistry (2012) 81: 31–41

Publications 2011

Bihani SC, Das A, Nilgiriwala KS, Prashar V, Pirocchi M, Apte SK, Ferrer JL and Hosur MV
X-ray structure reveals a new class and provides insight into evolution of alkaline phosphatases.
PLoS One (2011) 6 (7): e22767

Brillet K, Reimmann C, Mislin GL, Noel S, Rognan D, Schalk IJ and Cobessi D
Pyochelin enantiomers and their outer-membrane siderophore transporters in fluorescent pseudomonads: structural bases for unique enantiospecific recognition.
Journal of the American Chemical Society (2011) 133(41): 16503-16509

Lassaux P, Traore DA, Loisel E, Favier A, Docquier JD, Sohier JS, Laurent C, Bebrone C, Frere JM, Ferrer JL and Galleni M
Biochemical and structural characterization of the subclass B1 metallo-beta-lactamase VIM-4.
Antimicrobial Agents and Chemotherapy (2011) 55 (3): 1248-1255

Le Maire A, Gelin M, Pochet S, Hoh F, Pirocchi M, Guichou JF, Ferrer JL and Labesse G
In-plate protein crystallization, in situ ligand soaking and X-ray diffraction.
Acta Crystallographica Section D: Biological Crystallography (2011) 67 (9): 747-755

Publications 2010

Labar G, Bauvois , Borel, F, Ferrer J-L, Wouters J, and Lamber D, “Crystal structure of the human monoglyceride lipase, a key actor in the endocannabinoid signalling.” ChembioChem 11(2)(2010), 218-27.64.

Das A, Mahale S, Prashar V, Bihani S, Ferrer J-L, Hosur M, “X-ray snapshot of HIV-1 protease in action: observation of tetrahedral intermediate and its SIHB with catalytic aspartate”, JACS 132(18) (2010), 6366-6373.

Robin A , Cobessi D, Curien G, Robert-Genthon M. Ferrer J-L, and Dumas R, “A new mode of dimerization of allosteric enzymes with ACT domains revealed by the crystal structure of the aspartate kinase from Cyanobacteria”, JMB 399 (2010), 283-293.

Girard E, Fourme R, Ciurko R, Joly J, Bouis F, Legrand P, Jacobs J, Dhaussy A-C, Ferrer J-L, Mezouar M and Kahn R, “Macromolecular crystallography at high pressure with pneumatic diamond-anvil cells handled by a 6-axis robotic arm”, J. of Applied Cryst., 43(4) (2010), 762-768.

Zhao N, Guan J, Ferrer J-L, Engle N, Chern M, Ronald P, Tschaplinski TJ, and Chen F, “Biosynthesis and emission of insect-induced methyl salicylate and methyl benzoate from rice”, Plant Physiology and Biochemistry 48 (2010), 279-287.

Publications 2009

Bihani S, Das A, Prashar V, Ferrer J-L, and Hosur MV, “X-ray structure of HIV-1 protease in-situ product complex”. Proteins 74(3) (2009), 594-602.

Borel F, de Groot A, Juillan-Binard C, de Rosny E, Laudet V, Pebay-Peyroula E, Fontecilla-Camps J.C, Ferrer J-L, “Crystal structure of the ligand-binding domain of the retinoid X receptor from the ascidian Polyandrocarpa misakiensis”, Proteins 74(2) (2009), 538-542.

Traoré D.A, El Ghazouani A, Jacquamet L, Borel F, Ferrer J-L, Lascoux D, Ravanat J-L, Jaquinod M, Blondin G, Caux-Thang C, Duarte V, and Latour J-M. “Structural and functional characterization of 2-oxo-histidine in oxidized PerR protein”, Nat. Chem. Biol. 5(1)(2009), 53-59.

Jacquamet L, Joly J, Bertoni A, Charrault P, Pirocchi M, Vernede X, Bouis F, Borel F, Périn J-P, Denis T, Rechatin J-L, Ferrer J-L. “Upgrade of the CATS Sample Changer Of the FIP-BM30A at the ESRF: Towards a Commercialized Standard”, JSR 16 (2009), 14-21.

Kumar M, Jagtap DD, Mahale SD, Prashar V, Kumar A, Das A, Bihani SC, Ferrer J-L, Suresh C, Hosur MV, and Ramanadham M, “Crystallization and preliminary X-ray diffraction analysis of human seminal plasma protein, PSP94”, Acta. Cryst. F65 (2009), 389-391.

Jacquamet L, Traoré D.A, Ferrer J-L, Proux O, Testemale D, Hazemann J-L, Nazarenko E, El Ghazouani A, Caux-Thang C, Duarte V, Latour J-M, “Structural characterization of the active form of PerR: insights into the metal-induced activation of PerR and Fur proteins for DNA binding”, Mol. Microbiol. 73(1) (2009), 20-31.

Emamzadah S, Petty Jr T, De Almeida1 V, Nishimura T, Joly J, Paszkowski J, Ferrer J-L, and Halazonetis T.D, “Cyclic olefin homopolymer-based microfluidics for protein crystallization and in situ X-ray diffraction”, Acta Crystallogr. D Biol. Crystallogr. 65(Pt 9) (2009), 913-20.

Dhouib K, Khan-Malek C, Pfleging W, Gauthier-Manuel B, Duffait R, Thuillier G, Ferrigno R, Jacquamet L, Ohana J, Ferrer J-L, Théobald-Dietrich A, Giegé R, Lorber B, Sauter C, “Microfluidic chips for the crystallization of biomacromolecules by counter-diffusion and on-chip crystal X-ray analysis”, Lab. On a Chip 9 (2009), 1412-1421.

Iwema T, Picciocchi A, Traore D, Ferrer J-L, Chauvat F, Jacquamet L, "Structural basis for delivery of intact [Fe2S2] cluster by monothiol glutaredoxin", Biochemistry 48(26) (2009), 6041-3.

Zhao N, Boyle B, Duval I, Ferrer J-L, Lin H, Seguin A, Mackay J, and Chen F, “SABATH Methyltransferases from White Spruce (Picea glauca): Gene Cloning, Functional Characterization and Structural Analysis”, Tree Physiology 29(7) (2009), 947-957.

Nilgiriwala K.S, Bihani S.C, Das A , Prashar V, Kumar M , ferrer J-L , Apte S.K, and Hosur M.V. “Crystallization and preliminary X-ray crystallographic analysis of PhoK, an extracellular alkaline phosphatase from Sphingomonas sp. BSAR-1”, Acta Cryst. F. 65 (2009), 917 – 919.

Baurin, S, Vercheval L , Bouillenne F , Falzone C , Brans A , Jacquamet L , Ferrer J.-L , Sauvage E , Dehareng D , Frère J.-M , Charlier P , Galleni M , and Kerff F. "Critical role of tryptophan 154 for the activity and stability of Class D beta-lactamases". Biochemistry 48(47) (2009), 11252-11263.

Prashar V, Bihani S, Das A, Ferrer J-L, and Hosur M, “Catalytic water co-existing with a product peptide in the active site of HIV-1 protease revealed by x-ray structure analysis”, PlosOne 4(11) (2009), e7860.

Bihani S , Das A , Prashar V , Ferrer J-L , and Hosur M.V , “Resistance Mechanism revealed by Crystal Structures of unliganded nelfinavir-resistant HIV-1 protease non-active site mutants N88D and N88S”, Biochem. Biophys. Res. Commun., 389(2) (2009), 295-300.

Publications 2008

Bauvois C, Jacquamet L, Huston AL, Borel F, Feller G and Ferrer JL
Crystal structure of the cold-active aminopeptidase from Colwellia psychrerythraea, a close structural homologue of the human bifunctional leukotriene A4 hydrolase.
Journal of Biological Chemistry (2008) 283(34): 23315-23325

Curien G, Biou V, Mas-Droux C, Robert-Genthon M, Ferrer JL and Dumas R
Amino acid biosynthesis: new architectures in allosteric enzymes.
Plant Physiology and Biochemistry (2008) 46(3): 325-339

Ferrer JL, Austin MB, Stewart Jr C and Noel JP
Structure and function of enzymes involved in the biosynthesis of phenylpropanoids.
Plant Physiology and Biochemistry (2008) 46(3): 356-370

Lafaye C, Iwena T, Ferrer JL, Kroll JS, Griat M and Serre L
Preliminary crystallographic data of the three homologues of the thiol-disulfide oxidoreductase DsbA in Neisseria meningitidis.
Acta Crystallographica Section F Structural Biology Crystallography Communication (2008) 64(Pt 2): 111-114

Loisel E, Jacquamet L, Serre L, Bauvois C, Ferrer JL, Vernet T, Di Guilmi AM and Durmort C
AdcAII: A new pneumococcal Zn-binding protein homologous with ABC transporters: biochemical and structural analysis.
Journal of Molecular Biology (2008) 381(3): 594-606

Tao Y, Ferrer JL, Ljung K, Pojer F, Hong F, Long JA, Li L, Moreno JE, Bowman ME, Ivans LJ, Cheng Y, Lim J, Zhao Y, Ballaré CL, Sandberg G, Noel JP and Chory J
Rapid synthesis of auxin via a new tryptophan-dependent pathway is required for shade avoidance in plants.
Cell (2008) 133(1): 164-176

Zhao N, Ferrer JL, Ross J, Guan J, Yang Y, Pichersky E, Noel JP and Chen F
Structural, biochemical, and phylogenetic analyses suggest that indole-3-acetic acid methyltransferase is an evolutionarily ancient member of the SABATH family.
Plant Physiology (2008) 146(2): 455-467

Publications 2007

Fieulaine S, Lunn JE and Ferrer JL
Crystal structure of a cyanobacterial sucrose-phosphatase in complex with glucose-containing disaccharides.
Proteins (2007) 68(3): 796-801

Publications 2006

Das A, Prashar V, Mahale S, Serre L, Ferrer JL and Hosur MV
Crystal structure of HIV-1 protease in situ product complex and observation of a low-barrier hydrogen bond between catalytic aspartates.
Proceedings of the National Academy of Sciences U S A (2006) 103(49): 18464-18469

Ferrer JL, Dupuy J, Borel F, Jacquamet L, Noel JP and Dulic V
Structural basis for the modulation of CDK-dependent/independent activity of cyclin D1.
Cell Cycle (2006) 5(23): 2760-2768

Legrand P, Dumas R, Seux M, Rippert P, Ravelli R, Ferrer JL and Matringe M
Biochemical characterization and crystal structure of Synechocystis arogenate dehydrogenase provide insights into catalytic reaction.
Structure (2006) 14(4): 767-776

Mas-Droux C, Curien G, Robert-Genthon M, Laurencin M, Ferrer JL and Dumas R
A Novel Organization of ACT Domains in Allosteric Enzymes Revealed by the Crystal Structure of Arabidopsis Aspartate Kinase.
Plant Cell (2006) 18(7): 1681-1692

Pojer F, Ferrer JL, Richard SB, Bach TJ and Noel JP
Structural basis for the covalent inhibition of 3-hydrox-3-methylglutaryl-coenzyme A synthase by the b-lactone containing natural product F244.
Proceedings of the National Academy of Sciences U S A (2006) 103(31): 11491-11496

Traoré D, El Ghazouani A, Ilango S, Dupuy J, Jacquamet L, Ferrer JL, Caux-Thang C, Duarte V and Latour JM
Crystal structure of the apo-PerR-Zn protein from Bacills subtilis.
Molecular Microbiology (2006) 61(5): 1211-1219

Publications 2005

De Groot A, de Rosny E, Juillan-Binard C, Ferrer JL, Laudet V, Pierce RJ, Pebay-Peyroula E, Fontecilla-Camps JC and Borel F
Crystal structure of a novel tetrameric complex of agonist-bound ligand-binding domain of Biomphalaria glabrata retinoid X receptor.
Journal of Molecular Biology (2005) 354(4): 841-853

Ferrer JL, Zubieta C, Dixon RA and Noel JP
Crystal structures of alfalfa caffeoyl coenzyme a 3-o-methyltransferase
Plant Physiology (2005) 137(3): 1009-1017

Fieulaine S, Juillan-Binard C, Serero A, Dardel F, Giglione C, Meinnel T and Ferrer J-L
The crystal structure of mitochondrial (Type 1A) peptide deformylase provides clear guidelines for the design of inhibitors specific for the bacterial forms.
Journal of Biological Chemistry (2005) 280(51): 42315-42324

Fieulaine S, Lunn JE, Borel F and Ferrer JL
The structure of a cyanobacterial sucrose-phosphatase reveals the sugar tongs that release free sucrose in the cell
Plant Cell (2005) 17(7): 2049-2058

Meyer P, Liger D, Leulliot N, Quevillon-Cheruel S, Zhou CZ, Borel F, Ferrer JL, Poupon A, Janin J and van Tilbeurgh H
Crystal structure and confirmation of the alanine:glyoxylate aminotransferase activity of the YFL030w yeast protein.
Biochimie (2005) 87(12): 1041-1047

Verdecia MA, Larkin RM, Ferrer JL, Riek R, Chory J and Noel JP
Structure of the Mg-chelatase cofactor GUN4 reveals a novel hand-shaped fold for porphyrin binding
PLoS Biology (2005) 3(5): e151

Publications 2004

Austin M, Bowman M, Ferrer J L, Schröder J and Noel J
An aldol switch discovered in stilbene synthases mediates cyclization specificity of type III polyketide synthases.
Chemistry and Biology (2004) 11(9): 1179 - 94

Austin M, Izumikawa M, Bowman M, Udwary D, Ferrer J L, Moore B and Noel J
Crystal structure of a bacterial type III polyketide synthase and enzymatic control of reactive polyketide intermediates.
Journal of Biological Chemistry (2004) 279(43): 45162-74

Ferrer J L, Ravanel S, Robert M and Dumas R
Crystal structure of cobalamin-independent methionine synthase complexed with Zn, homocysteine and methyltetrahydrofolate
Journal of Biological Chemistry (2004) 279(43): 44235-44238

Graille M, Quevillon-Cheruel S, Leulliot N, Zhou C-Z, de La Sierra Gallay I L, Jacquamet L, Ferrer J-L, Liger D, Poupon A, Janin J and van Tilbeurgh H
Crystal Structure of the YDR533c S. cerevisiae Protein, a Class II Member of the Hsp31 Family
Structure (2004) 12(5): 839-847

Jacquamet L, Ohana J, Joly J, Borel F, Pirocchi M, Charrault P, Bertoni A, Israel-Gouy P, Carpentier P, Kozielski F, Blot D and Ferrer J
Automated analysis of vapor diffusion crystallization drops with an x-ray beam.
Structure (Camb) (2004) 12(7): 1219 - 1225

Jacquamet L, Ohana J, Joly J, Legrand P, Kahn R, Borel F, Pirocchi M, Charrault P, Carpentier P and Ferrer J L
A new highly integrated sample environment for protein crystallography
Acta Crystallography D Biological Crystallography (2004) 60(Pt 5): 888-94

Li de La Sierra-Gallay I, Collinet B, Graille M, Quevillon-Cheruel S, Liger D, Minard P, Blondeau K, Henckes G, Aufrère R, Leulliot N, Zhou C, Sorel I, Ferrer JL, Poupon A, Janin J and van Tilbeurgh H
Crystal structure of the YGR205w protein from Saccharomyces cerevisiae: close structural resemblance to E. coli pantothenate kinase.
Proteins (2004) 54(4): 776 - 783

Ohana J, Jacquamet L, Joly J, Bertoni A, Taunier P, Michel L, Charrault P, Pirocchi M, Carpentier P, Borel F, Kahn R and Ferrer J L
CATS: a cryogenic automated transfer system installed on the beamline FIP at ESRF.
Journal of Applied Crystallography (2004) 37 Part 1: 72-77

Publications 2003

Downes M, Verdecia MA, Roecker AJ, Hughes R, Hogenesch JB, Kast-Woelbern HR, Bowman ME, Ferrer J-L, Anisfeld AM, Edwards PA, Rosenfeld JM, Alvarez JGA, Noel JP, Nicolaou KC and Evans RM
A Chemical, Genetic, and Structural Analysis of the Nuclear Bile Acid Receptor FXR
Molecular Cell (2003) 11(4): 1079-1092

Verdecia MA, Joazeiro CAP, Wells NJ, Ferrer J-L, Bowman ME, Hunter T and Noel JP
Conformational Flexibility Underlies Ubiquitin Ligation Mediated by the WWP1 HECT Domain E3 Ligase
Molecular Cell (2003) 11(1): 249-259

Publications 2002

Ennifar E, Carpentier P, Ferrer J L, Walter P and Dumas P
X-ray-induced debromination of nucleic acids at the Br K absorption edge and implications for MAD phasing.
Acta Crystallographica D Biological Crystallography (2002) 58(Pt 8): 1262-8

Richard SB, Ferrer JL, Bowman ME, Lillo AM, Tetzlaff CN, Cane DE and Noel JP
Structure and mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase - An enzyme in the mevalonate-independent isoprenoid biosynthetic pathway
Journal of Biological Chemistry (2002) 277(10): 8667-8672

Zubieta C, Kota P, Ferrer J L, Dixon R and Noel J
Structural basis for the modulation of lignin monomer methylation by caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase.
Plant Cell (2002) 14(6): 1265 - 77

Publications 2001

Carpentier P, Rossat M, Charrault P, Joly J, Pirocchi M, Ferrer JL, Kaïkati O and Roth M
Synchrotron monochromator heating problem, cryogeneic cooling solution
Nuclear Instruments and Methods in Physics Research A (2001) 456(3): 163-176

Ferrer JL
Automated data processing on beamline FIP (BM30A) at ESRF.
Acta Crystallographica D Biological Crystallography(2001) 57(Pt 11): 1752 - 1753

Jez J M, Ferrer J L, Bowman M E, Austin M B, Schroder J, Dixon R A and Noel J P
Structure and mechanism of chalcone synthase-like polyketide synthases.
Journal of Industrial Microbiology and Biotechnology (2001) 27(6): 393-398

Pubications 2000

Gruez, A, Pignol, D, Zeghouf, M, Coves, J, Fontecave, M, Ferrer, JL and Fontecilla-Camps, JC
Four crystal structures of the 60 kDa flavoprotein monomer of the sulfite reductase indicate a disordered flavodoxin-like module [In Process Citation].
Journal of Molecular Biology (2000) 299(1): 199-212

Jez, J., J. Ferrer, M. Bowman, R. Dixon and J. Noel
Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase.
Biochemistry (2000) 39(5): 890-902

Jez, J. M., Austin, M. B., Ferrer, J. L., Bowman, M. E., Schroder, J. and Noel, J. P.
Structural control of polyketide formation in plant-specific polyketide synthases
Chemistry and Biology (2000) 7(12): 919-930