Institut de Biologie StructuraleGrenoble / France


Since its opening, the Institute has filed more than twenty patents at the European Patent Office (EPO) :

  • 25 are currently in force,
  • 9 patent applications are underway,
  • 16 patents have been abandoned.

IBS patents

Peptides including a binding domain of the viral phosphoprotein (P) subunit to the viral RNA free nucleoprotein (N0); n° de publication: WO2016009044; INSERM, CNRS, Université Claude Bernard Lyon 1; ENS Lyon; UJF; Volchkov V, Jamin M, Lawrence P, Yabukarski F.

Mutant NQ-Rhodopsin KR2; n° de publication : WO201612677; CEA, Forschungszentrum Julich gmbh, Max-Planck Forderung der Wissenschaften; Bamberg E, Bamann C, Gordeliy V, Gushchin I, Polovinkin V, Schevchenko V.

Conjugated molecules comprising a peptide derived from the cd4 receptor coupled to an anionic polypeptide for the treatment of AIDS; n° de publication : WO2016062854; CEA, Pasteur, CNRS, UGA, Université Paris Sud; Coic Yves-Marie, Lortat-Jacob Hugues, Baleux Francoise, Bonnaffe David.

Dispositif et procédé de caractérisation d’une particule; n° de publication : FR3021745; CEA; Kleman Jean-Philippe, Poulain Cedric, Rabaud David.

NADPH oxydase Proteins; n° de publication : WO2015162383; UJF, CNRS; Dupuy Jérôme, Hajjar Christine, Cherrier Mickaël, Fieschi Franck.

New Enzyme and Method for preparing 4-hydroxyl benzyl Alcohol and Derivatives thereof; n° de publication : WO2015091755; CEA, INRA; Berteau Olivier, Nicolet Yvain, Fontecilla-Camps Juan.

Novel uncharged reactivators against O-inhibition of human acetylcholinesterase; n° de publication : WO2015075082; Commissariat à l’Energie Atomique, CNRS, Institut recherche biomedicale Armées IRBA, Université de Rouen, Université de Strasbourg, UJF; Baati R; Nachon F, Friedel M; Verdelet T; Renou J; Weik M; Kliachyna M; Trouvey C; Renard PY; Mercey G; Jean L; Colletier JP; Sanson B; Santoni G; Nussbaum V.

Method of crystallization of membrane proteins and to compositions, devices and kits to conduct such method; n° de publication : EP2832741; CEA ; Gordeliy Valentin, Round Ekaterina, Borshchevskly Valentin, Gushchin Ivan, Polovinkin Vitaly.

Method for preparing c1q recombinant protein; n° de publication : WO2014057437; CEA; Thielens N., Bally I.

Labeled chiral alpha-hydroxy ketoacid derivatives, a process for preparing said derivatives and their use; n° de publication : WO2014024151; CEA, CNRS; Gans P ; Boisbouvier J ; Plevin M; Kerfah R; Pessey O

Use of new or known lanthanide(III) complex compound for resolution of three dimensional structure of a protein entity by X-ray diffraction in crystallography; n° de publication : FR20120055216; Université Blaise Pascal Clermont, Ecole nationale supérieure des arts et metiers, CNRS, CEA, UJF ; Gautier Arnaud, Canet Jean-Louis, Nauton Lionel, Girard Eric, Talon Romain

New conjugated molecules comprising a peptide derived from the CD4 receptor coupled to a polyanion for the treatment of AIDS; n° de publication : WO2012126833; Institut Pasteur, CNRS, Université Paris sud; Baleux Françoise, Bonnaffe David, Lortat-Jacob Hugues

Sulphated arabinogalactans apiogalacturonans and sulphated heteroglycans for treating diseases caused by the influenza virus; n° de publication : WO2012093234; Elycitil, CNRS, INSERM, CEA; Bartoli J., Bonnet S., Cosset F.L., Darblade B., Ferraris O., Havet S., Heyraud A., Lina B., Livache T., Lortat-Jacob H., Sadir R., Szécsi J., Vo H.

Peptides capable of forming a covalent complex, and uses thereof; n° de publication : WO2012127060; CEA; Vernet T, DiGuilmi A.M.

Method for detecting and quantifying microorganisms; n° de publication : WO2012073202; CEA; Roupioz Y, Calemczuk R, Vernet T., Livache T., Bouguelia Sihem, Durmort C.

Device and method for crystallising inorganic or organic substances; n° de publication : WO211FR52121; Université Joseph Fourier ; M.Spano

Process for the specific isotopic labeling of methyl groups of Val, Leu and Ile; n° de publication : WO2011083356; CEA, CNRS, Université Joseph Fourier; Gans P ; Ayala I ; Boisbouvier J ; Hamelin O.

Use of derivatives of indoles for the treatment of cancer. n° de publication : WO2010150211; CNRS; Guillou Catherine, Kozielski Frank, Labriere Christophe, Gueritte Françoise, Tchnernuik Sergey, Dimitrios Skoufias, Claude Thal, Henri-Philippe Husson

Device and Method for Holding and Releasing a Metallic Sample Holder, and Use of this Device; n° de publication : WO2010001260; CEA, CNRS; Ferrer Jean-Luc, Jacquamet Lilian, Izier Catherine

Conjugated molecules comprising a peptide derived from the cd4 receptor coupled to a polyanion for the treatment of aids; n° de publication : WO2009098147; Institut Pasteur, CEA; Baleux Françoise, Bonnaffe David, Lortat-Jacob Hugues, Loureiro-Morais Latino

Cross linking agents. Brevet International, n° de publication : W02010100238; CNRs, Université de Montpellier, Université de Montpellier 2; Martinez Jean, Subra Gilles, Goubet Christine, Paramelle David, Forest Eric, Michael Heymann, Geourjon Christophe

[NiFe] hydrogenases having an improved resistance to dioxygen, process for obtaining them and their application ([NiFe] hydrogenase mutante possédant une résistance accrue à l’oxygène). Brevet International, n° de publication : WO2009019613, date de publication 2009/02/12 ; CEA, CNRS, Cournac Laurent, Volbeda Anne, Jousset Emeline,Dementin Sebastien, Rousset Marc, Guenedey Genevieve, Leger Christophe, Leroux Fanny, Champ Stéphanie

Method and gripping device for automtically transferring a sample container from a storing location to an analysis location and use of said device (Procédé et dispositif de préhension pour le transfert automatique d’un récipient pour échantillons depuis un emplacement de stockage jusqu’à un emplacement d’analyse, et utilisation d’un tel dispositif) ; Brevet International, n° de publication : WO2009010886 ; date de publication 2009/01/21 ; CEA, CNRS; Ferrer Jean-Luc, Jacquamet Lilian, Bertoni Alain

CD4-receptor-derived peptides and method for the preparation thereof (Nouveaux peptides activés, purifés et isolés, dérivés du récepteur CD4 (Mini-CD4) et leur procédé de préparation); Brevet International, n° de publication : WO2008015273, date de publication 2008/02/08, INSTITUT PASTEUR, CEA; Baleux Francoise; Lortat Jacob Hugues; Bonnaffe David

Anti-hiv composition, production method thereof and medicament (Composition anti-VIH, procédé de fabrication et médicament); Brevet International, n° de publication WO03089000 , date de publication 2003/10/30,CEA; CNRS; Lortat-Jacob Hugues; Vita Claudio; Vives Romain

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