The candidate will characterize the interaction of pneumococcal penicillin-binding proteins (PBPs) with peptidoglycan fragments. Pneumococcus is an important human pathogen that resists penicillin through the expression of peptidoglycan transpeptidases (PBPs) with reduced affinity. These enzymes retain their transpeptidase activity without reacting with penicillin. The interaction of PBPs with penicillin is well known, while their interaction with peptidoglycan remains unknown.
Contract duration : 24 months
Deadline to apply : 25/04/25