Kadlec Team

Team leader: Jan Kadlec

The goal of our team is to understand molecular mechanisms underlying the mechanisms of RNA biogenesis and degradation. We also investigate the mechanisms the activities of epigenetic regulatory complexes such as histone acetyltransferases and methyltransferases. To obtain molecular insights into the functions of important RNA and chromatin regulatory complexes and their role in human disease, we use an interdisciplinary approach combining biochemical, biophysical and structural analyses (cryo-electron microscopy and X-ray crystallography and ) with cell biology and genetics.

Team Members
Helena Fahy, Anne-Emmanuelle Foucher, Arije Safa, Jan Kadlec, Étienne Dubiez