Group leader: Martin Blackledge
Presentation
Welcome to the web-page of the Protein Dynamics and Flexibility by NMR group at the IBS. The overarching interest of our research group lies in the study of protein dynamics, developing and applying experimental NMR methods, in association with other biophysical and simulation based approaches, to characterize the role of conformational flexibility in biological function on a broad range of time and length scales, from molecular recognition dynamics in folded proteins, to reorganizational dynamics of large multidomain assemblies exhibiting extensive protein disorder.
Key words
NMR, conformational flexibility, intrinsically disordered proteins, protein dynamics, protein structure determination, protein folding, functional dynamics.