Methods development
Lorenzo Gaifas, Brandon Le Bon, Ambroise Desfosses, Irina Gutsche
As electron microscopists, we are always keen in gaining a deep understanding of different image processing algorithms and workflows, and using state-of-the art software. Where necessary, we develop our own tools and share them with the community.
To enable interactive visualisation and annotation of cryo-ET data, we developed blik, an open-source napari plug-in built on the python scientific ecosystem. We also maintain a number of tools for working with established software suites : cs2star for Relion-CryoSPARC conversion, waretomo for batch processing with Warp and AreTomo.
Together with an open and international group of cryo-ET software enthusiasts, we champion the Teamtomo project, a community effort to develop a unified but modular ecosystem of libraries for cryo-ET image processing.
We also contribute to the development of the software for helical symmetry determination, helixplorer, and participate in solving structures of particularly challenging helical assemblies.
Collaborations :
– Leandro Estrozi, MEM, IBS
– Alister Burt, Genentech, USA
– Daniel Castaño Díez, CSIC, Bilbao, Spain