A protocol combining atomic force microscopy with small angle X-ray scattering appeared in the review Nature Protocols. To know more, consult the IBS highlights.
Uroda T, Chillon I, Annibale P, Teulon J-M, Pessey O, Karuppasamy M, Pellequer JL and Marcia M (2020) Visualizing the functional 3D shape and topography of long noncoding RNAs by single-particle atomic force microscopy and in-solution hydrodynamic techniques. Nat. Protoc. 15 : 2107-2139.