Previous meetings and workshops

7th School of Integrative Structural Biology - October 09 to 16, 2020 - Oleron

Initially scheduled in june, this school, organized by RéNaFoBIS (Réseau National de Formation en Biologie Structurale Intégrative), aims at providing training for graduate students in the field of Integrative Structural biology. Lectures are given mainly in French, slides are in English, in order to make it easier for non-French speaking participants to follow. During practical sessions (TP), English-speaking groups can be proposed if needed.
D. Housset (IBS/IRAPS group) is co-organizer. IBS scientists will give lectures and tutorials.
To know more (in french only).

PSB Spotlight meeting on "Mass Spectrometry" - Tuesday 13 October 2020 - Webinar

The Partnership for Structural Biology (PSB) is pleased to announce its 7th PSB Spotlight meeting that will focus on "Mass Spectrometry" and will take place on Tuesday 13 Octobre 2020 as a webinar.
The meeting is opened to non-specialists and aims to illustrate the great variety of applications of mass spectrometry to study single proteins, complexes or even large particles such as viruses.
For further information, please check the programme.
Please contact a member of the organising committee for link to the webinar : Elisabetta Boeri Erba (IBS), Luca Signor (IBS), Sagar Bhogaraju (EMBL), Montse Soler Lopez (ESRF), Juliette Devos (ILL) and Florent Bernaudat (PSB)

CANCELLATION, POSTPONEMENT OR VISIOCONFERENCE for meetings (co-)organized by IBS until May 30, 2020

From March 16 2020, the Hercules European School scheduled in Grenoble from 02 March to 03 April 2020 will keep going via visoconference.

The 2020 edition of the Tutorial in Macromolecular Crystallography, scheduled from 16 to 20 March 2020 on EPN Campus is cancelled.

Les Houches School of Physics "Fluorescence markers for advanced microscopy" scheduled from March 29 to April 03, 2020, is cancelled.

The 4th scientific meeting of the GDR GAG scheduled from May 25 to 26, 2020 is postponed to automn 2020.

The TSRC Protein Dynamics Workshop due to be hold in Les Houches in June is postponed.

FEBS INSTRUCT MOBIEU Practical Course HyThaBio 2020 - January 26 to 31, 2020 - IBS

A practical course about ’Hydrodynamic and thermodynamic analysis of biological macromolecules and their interactions : multi-method approaches and global data analyses’ will take place at the IBS from January 26 to 31, 2020.
This course, co-organized by IBS, provides theoretical and practical training in data analysis in several modern biophysical methods for monitoring and quantifying molecular interactions – analytical ultracentrifugation, isothermal titration calorimetry, surface plasmon resonance, microscale thermophoresis, and fluorescence-based techniques ; additional related methods are introduced in lectures. The course put emphasis on the complementarity of these different methods in the field of macromolecular biology and on the combined analysis of datasets coming from different methods, using the programs developed by P. Schuck (NIH USA).
Information and registration on the dedicated website.
Deadline for applications : October 30, 2019

2nd workshop on Advanced Diffraction Techniques for Biology - 19 to 22 November 2019 - EPN Campus

The course will cover X-rays, neutrons and electrons diffraction by crystals of biological macromolecules. Various techniques will be investigated :
• Macromolecular crystal growth
• In situ (in plate) X-ray diffraction
• Serial X-ray crystallography
• Time resolved X-ray crystallography
• Neutron diffraction
• Electron diffraction of nano-crystals
with the aim of solving de novo structures, searching ligands, elucidating reaction mechanisms...
This 4 days course will combine theoretical lectures and practicals on ESRF beamlines and other EPN instruments. It is dedicated to researchers (advanced PhD, PostDoc, Scientist) interested in macromolecular structural studies at atomic resolution using crystallographic approaches.
To apply, please, send a short CV (1 page max.) and a motivation letter to marta.elzo-aizarna@ibs.fr before September 30, 2019.
The registration is free and includes accommodation and meals on the EPN campus. Selected applicants will be notified by e-mail on October 15, 2019. Participants will have to pay for their travel expenses. More details about the workshop can be found on the dedicated web site.
ADTB is funded by IBS, EMBL, ESRF, CBS, FRISBI, CRISTECH, AFC, UGA, Grenoble INP, CNRS, CEA

Fluo Day - November 21, 2019 - IAB

Program(me)

On Thursday November 21st, the life science imaging facilities of Grenoble (including IBS) organize the fourth edition of FluoDay that will take place at the Institute of Advanced Biosciences (IAB).
This year, Fluoday will be focused on 3D microscopy and Image analysis in order to adress following questions :

• How would expert techniques (STORM, LightSheet, Adaptative Microscopies) enhance your imaging experience ?
• What are the possibilities of 3D EM ?
• How will Artificial Intelligence help your Image Analysis ?
  The presentations and animation of the round table will be performed by local and invited experts.
  The event is free, a “Raclette” will be offered at midday, but registration is mandatory, with only 80 entries ;-)
  Register a poster of your research dealing with imaging, and take a shot at winning the Best Poster Award ! (and maybe new good ideas)
  REGISTRATION : https://forms.gle/5nq4Syanm3P6vF1j6

Cryo-EM Winter Workshop - 5, 6 & 7 November 2019 - EPN

This 2.5-day practical winter workshop on sample preparation for single particle cryo-EM, jointly organised by the ESRF, EMBL Grenoble, ILL and the IBS, was held from November 5th to 7th 2019. This was the third of a series of practical hand-on workshops and is aimed at PhDs, PostDocs and scientists new to the field of single particle cryo-EM. During the course, participants learned theoretical and practical aspects of sample preparation for single particle cryo-EM including prior quality control by negative staining. Dedicated website

Organisers & instructors : Grégory Effantin (IBS), Guy Schoehn (IBS), Michael Hons (EMBL), Daouda Traoré (ILL), Isai Kandiah (ESRF) and Christoph Mueller-Dieckmann (ESRF). Administrative assitant : Claudine Roméro (ESRF).

11th AFM BioMed 2019 International School - October 21-25, 2019 - IBS

The AFMBioMed International School offers an introduction to atomic force microscopy in life and health sciences. Students, post-doctoral fellows, researchers, technicians and platform engineers come to deepen their knowledge but also to learn about new cutting-edge developments both at the instrumental and application levels. The school covers both fundamentals and expert questions with the possibility for students to bring their own samples. This summer school allows, thanks to the AFMBioMed network, to make contacts and establish scientific collaborations between all participants and supervisors. The school runs for a full week, usually from Monday to Saturday and includes morning classes (10 x 1h30) and practical work in the afternoons (between 4 and 5 hours per group each afternoon). Depending on the number of machines available, the school targets about 20 students. This school is organized in collaboration with the ILL and the European project ITN Phys2BioMed. For more information : http://www.afmbiomed.org/grenoble-2019.aspx.
Contact : Jean-Luc Pellequer

3rd Train2Target annual meeting - October 16 to 18, 2019 - IBS

The 3rd annual meeting of the European Train2Target network is organised by J.P Simorre Cedric, Laguri and Tiago Baeta (IBS/NMR) from 16 to 18 October. This network aims to provide leads for a new generation of innovative antibacterial agents to treat infections with multi-resistant pathogens. These meetings not only give the people involved in Train2Target the possibility to meet in person, but to exchange experiences and to discuss achieved tasks and future goals.

Phages in Grenoble - October 08 & 09, 2019 - IBS

The "PHAGES in Grenoble" workshop will take place on October 8 and 9, 2019 at the Institute for Structural Biology (IBS), on the EPN (European Photon & Neutron Campus) campus in Grenoble.
After Montpellier-2015, Marseille-2016, Gif-sur-Yvette-2017 and Bordeaux-2018, this is the fifth symposium on phages organized by the Pluridisciplinary Thematic Network PHAGES.fr. Its objective is to bring together the community of French teams involved in bacteriophage research, while being open to international teams. Four foreign scientists specializing in bacteriophages in different fields will give a plenary lecture. The exchange language will be English.

The themes to be addressed will provide an overview of current research and promote scientific interactions between teams working in various and complementary fields :
 Ecology and Evolution
 Structure and Assembly
 Phage-host interaction
 Application in Therapy and Biotechnology

Details and registration on the dedicated website.

EMBO practical course on "Small angle neutron and X-ray scattering from biomacromolecules in solution" - 23 – 27 September 2019 - EPN Campus

Taking advantage of the location of the European Synchrotron Radiation Facility (ESRF) and the Institut Laue Langevin (ILL) on the same scientific campus in Grenoble, this EMBO course, organized by PSB, will focus on the complimentary use of X-ray and neutron small angle scattering for the determination of the structures of biological macromolecules.
Particular attention will be paid to sample preparation and the analysis and interpretation of SAS data in a biological context. The aim of this course is to enable the participants to maximise the information gained from the SAS technique in their future experiments.
Franck Gabel (IBS) is organizer with co-organizers Anne Martel (ILL), Petra Pernot (ESRF) and Martha Brennich (EMBL)
Details on the dedicated website.

Alpine Conference on Magnetic Resonance in Solids - 15–19 September 2019 Chamonix-Mont-Blanc, France

The Alpine conference is a high-level international forum for the discussion of recent developments and applications in the field of magnetic resonance in solids. The conference focuses on novel concepts, methods and instrumentation, as well as applications in fields including physics, chemistry, biology and materials science. Beyond its original and still core focus on solid-state NMR, the Alpine Conference will in 2019 welcome contributions from EPR and MRI in solids.
The main program of the conference consists of plenary lectures and contributed communications, with round table sessions.
Paul Schanda (IBS/NMR) is part of the Organising Committee of this biennially conference and will give a lecture. To know more

ESONN 2019 - August 25 to September 14, 2019 - Grenoble

From 2004, ESONN is a three-week course aimed at providing training for graduate students, postdoctoral and junior scientists from universities and laboratories, all around the world, in the field of Nanosciences and Nanotechnologies. The academic and practical courses will cover aspects such as the elaboration, characterization and functionalities of nano-objects.
Half of the formation is devoted to practicals, which are held in Grenoble clean room facilities at the Inter-university Centre for MicroElectronics (CIME) and in research laboratories.

IBS scientists are involved in practical courses for the biological session :

• "Proteins and nanoparticle assemblies and interactions by AUC and SEC/MALS" by Christine Ebel and Aline Le Roy (IBS/M&P) - (PDF)
• "Cell imaging analysis of protein interactions and dynamics in living cells" by Françoise Lacroix, Joanna Timmins & Jean‐Philippe Kleman (IBS/IRPAS) - (PDF)
• "Study of biomolecular interactions by surface plasmon resonance biosensor analysis (BIAcore technology)" by Jean-Baptiste Reiser (IBS/IRPAS) - (PDF)
• "Cryo-Electron Microscopy : sample preparation and visualization using a Polara and a Krios electron microscope both equipped with a direct electron detector" by Guy Schoehn and Isai Kandiah (IBS/MEM and ESRF) - (PDF)

Information & registration on ESONN web site.

PSB Symposium "Macromolecules in action " - 04 & 05 July 2019 - EPN Campus

After the success of its first symposium on cryo-EM in 2017, the Partnership for Structural Biology (PSB) is pleased to announce a second symposium on "Macromolecules in action " which will take place on 4-5 July 2019 on the EPN campus

The aim of this meeting is to illustrate how the big biological questions are resolved by combining key methods in structural biology (eg X-ray and neutron crystallography, cryo-EM, NMR and small angle scattering - SAXS and SANS) with other complementary approaches, enhancing our understanding of the dynamic behaviour of macromolecular complexes in the cell.

To know more about the programme, call for abstracts, PSB Young investigator’s award, venue and registration, please consult the dedicated website.

6th School of Integrative Structural Biology - June 21 to 28, 2019 - Oleron

This school, organized by RéNaFoBIS (Réseau National de Formation en Biologie Structurale Intégrative), aims at providing training for graduate students in the field of Integrative Structural biology.
D. Housset (IBS/IRAPS group) is co-organizer. IBS scientists (Catherine Bougault (IBS/NMR) and Dominique Housset) will give lectures and tutorials. To know more (in french only).

INSERM international Workshop on GlycosaminoGlycans - 19-21th of June 2019 - Bordeaux

The goal of this workshop, organized by Romain Vives (IBS, Grenoble) and Dulce Papy Garcia (Gly-CRRET, UPEC, Créteil), to put an emphasis on the technological developments and breakthroughs that led to progress in the understanding of GAG structure and biological functions, as well as the perspectives of applications in diagnostics and therapy.

The workshop will include 4 main sessions focusing on :
 GAG Biosynthesis and Metabolism
 GAG-protein interactions and physiophatological conditions
 Technological and methodological approaches for GAG analysis
 GAGs : from bench to bedside
Registration are open (deadline 15/04) and all details can be found on the dedicated website.

IBS Scientific Day - June 13, 2019 - EPN Campus

Programme 2019

The IBS 2019 Scientific Day took place on the EPN campus on June 13 with about 200 participants. In addition to plenary lectures, the 2019 programme included Duo presentations, ERC/ANR presentations in 180s, a presentation by Diego Gauto (Laureate of the IBS Young Researcher Publication Prize 2018/2019) and a lecture by an invited speaker. A poster session by 2nd year doctoral and post-doctoral students was also organized after lunch. On this occasion, the Best Poster Award was given to Guillaume Fouet (IRPAS group) for his work on ’C1q interaction with the immunoglobulin-like receptor LAIR-1’. Finally, the day ended with a friendly dinner on the lawns in front of the IBS.

Oxford-Grenoble Alpes twinning symposium - 27-28 May 2019 - ILL Chadwick amphitheater

In the frame of the celebrations of the 30 year twinning of the towns of Oxford and Grenoble, this symposium will emphasis on 30 years of collaborative research in Advanced Materials and biological Structures.
It will focus on chemistry, material science (including magnetism, ferroelectricity and plasticity), soft condensed matter and biophysics. For more information on the symposium and to register, please visit the dedicated website.

International workshop on sample preparation for cryo electron microscopy - May 21-23, 2019 - EPN campus

A two-and-a-half day practical workshop on sample preparation for negative staining and cryo electron microscopy is jointly organized by ESRF, EMBL Grenoble and IBS on the EPN campus from 21 to 23 May 2019. This is the second practical workshop in a series that began in 2018. This workshop is intended for doctoral students, post-doctoral fellows and young scientists starting in the field of cryo-EM. Participants (a dozen out of 70 candidates) will be able to learn the theoretical and practical aspects of sample preparation in negative staining and cryo-microscopy, then test the samples on different ESRF, EMBL and IBS electron microscopes.
Organizers and instructors : Grégory Effantin (IBS), Michael Hons (EMBL), Isai Kandiah (ESRF), Guy Schoehn (IBS) and Christoph Mueller-Dieckmann (ESRF). ThermoFisher Scientific actively supports this workshop by providing an instructor and a Vitrobot freezing robot.

Hercules course - March 18 to April 19, 2019 - Grenoble

This one month course, coordinated by the Université Grenoble Alpes, is designed to provide training for students, postdoctoral and senior scientists from European and non-European universities and laboratories, in the field of Neutron and Synchrotron Radiation for condensed matter studies (Biology, Chemistry, Physics, Materials Science, Geosciences, Industrial applications). It includes lectures, practicals and tutorials, visits of Large Facilities and a poster session.
The course is held in Grenoble at the Polygone Scientifique Louis Néel. This is close to partner institutions where practicals and tutorials will take place (EMBL, ESRF, IBS, ILL, CEA, CNRS).
A special seven days programme is included , in a partner institution among European Large instruments. In 2019, due to the long ESRF shutdown, two weeks (out of the five of the school) will be spent in two different partner institutions among ALBA, KIT, DESY, Elettra & Fermi, Swiss Light Source, SOLEIL.

The school includes a common part and two parallel sessions :
 Biomolecular, soft condensed matter structure & dynamics
 Physics and chemistry of condensed matter

F.Gabel (IBS/ELMA) is co-director of the HERCULES school for the biology session and many IBS scientists give lectures and tutorials.

For details, please have a look on the website of the course. Deadline for application 15 October 2018.

Advances Isotopic Labeling Methods for Integrated Structural Biology International Workshop (AILM 2019) - March 26th to 29 th, 2019 - EPN Campus Grenoble

The AILM workshop will focus on the development of isotopic labelling techniques and their application to the study of biomolecular structure and dynamics. Conference sessions covered developments in isotopic labelling strategies for NMR spectroscopy, mass spectrometry, neutron scattering and diffraction, as well as methodological approaches, such as co-expression, segmental labelling, specific labelling, labelling with paramagnetic tags, and sample production in vitro or in eukaryotic cells. The program also included elegant examples of the application of these methods to challenging systems such as high molecular weight proteins and nucleic acids complexes or direct studies of biomacromolecules in cells or tissues.

A Symposium in honor of Dr. Dominique MARION’s retirement will take place on Monday March 25th 2019 and a practical school will follow the international workshop from March 29 to April 05.

Information and registration

Organizers : Jerome Boisbouvier (IBS/NMR), Bruno Kieffer (IGBMC - Strasbourg), Michael Plevin (University of York - UK) and Carine Tisné (IBPC – Paris)

PSB Spolight on Imaging - Tuesday March 19th, 2019 - EPN campus.

The aim of this meeting is to illustrate how different experimental imaging techniques can be combined to perform various biological studies at different scales, ranging from single particles to large biology structures (e.g. bones). Morning will be devoted to scientific seminars on different types of imaging : electron microscopy, nanoSIM, X-ray fluorescence, X-ray holography, super-resolution imaging, cryoelectronic neutron tomography and nano-tomography. Several practicals for a limited number of people will be available in the afternoon : AFM, super resolution microscopy, 4D microscopy, cell microscopy (sample preparation), cryo electron microscopy and X-ray and neutron tomography data processing. Seminars are open to all, practicals need registration.
This meeting is organized by Florent Bernaudat (ESRF), Sylvain Bohic (ESRF/Inserm), Dominique Bourgeois (IBS), Wojtek Galej (EMBL), Guy Schoehn (IBS) and Alessandro Tengattini (ILL) under the auspices of the PSB.
Program and registration on the dedicated website.

2019 edition of the Tutorial in Macromolecular Crystallography - 04 to 08 March 2019 - EPN Campus

Fundamental aspects of crystallography will be treated in theoretical sessions and 3 practical sessions of 2h each which will treat case studies. The tutorial will be given in English. The theoretical sessions will be a mix of lecture and problem solving (rather basic, more of the pencil and paper type).
The tutorial (limited to 20 participants) is aimed in the first place at graduate students at Université Grenoble-Alpes and on EPN campus who have a priority in registration. The tutorial counts for 3 ECTS credits needed for the "Ecole doctorale" of the UGA.
The tutorial is furthermore open to post-docs and staff of the EPN / PSB partners.

Workshop on the reconstitution of membrane proteins into liposomes and nanodiscs - November 20 & 21, 2018 - IBS

In the frame of GDR3696 - ProMemMoCe Membrane Proteins, the IBS, the Institut Curie and the IBPC are organizing a workshop on the reconstitution of membrane proteins into liposomes and nanodiscs. The workshop will take place at IBS (Grenoble), from Tuesday November 20, 2pm till Thursday November 22 around 5pm.
Registration is limited to a dozen participants and priority is given to young researchers (pre-docs, docs, postdocs,...) whose research is in line with the workshop program.
Accommodation and catering costs will be covered by the GdR, transport costs will be covered by the laboratories. Interested persons are invited to contact Martin Picard (martin.picard(at)ibpc.fr) before October 19, specifying their host laboratory and, in a few lines, the themes they are developing.
Organizing Committee : Aline Le Roy (IBS, Grenoble), Cécile Breyton (IBS, Grenoble), Manuela Dezi (Sorbonne University, IMPMC, Institut Curie), Hager Souabni (IBPC, Paris), Dhenesh Puvanendran (IBPC, Paris), Martin Picard (IBPC, Paris).

How cryo Electron Microscopy meets chemical structure - Paris - November 14-15th, 2018

This meeting will be an opportunity to review the progress of cryoEM and its role in understanding the complexity of life. This scientific day will feature a series of lectures by international leaders in the field and younger researchers.
Oral and poster presentations, selected from abstracts, are planned. The abstract submission form is to be downloaded and returned completed, from the registration site. The deadline for abstract submission is 31 October 2018. All papers (oral and poster) will be in English.

The symposium organized by ITMO Molecular and Structural Bases of Life (BMSV) of the Aviesan Alliance entitled "How cryo Electron Microscopy meets chemical structure". Guy Schoehn (IBS/MEM) is a member of the Scientific Committee and Hugues Lortat-Jacob (IBS/SAGAG) and Hugues Nury (IBS/MEMBRANE) will give lectures.

1st Workshop on Advanced Diffraction Techniques for Biology - 05-09 November 2018 - EPN campus, Grenoble

It is our pleasure to announce the first workshop on Advanced Diffraction Techniques for Biology in the EPN campus at Grenoble, France.
The course will cover X-rays, neutrons and electrons diffraction by crystals of biological macromolecules. Various techniques will be investigated :
• Macromolecular crystal growth
• In situ (in plate) X-ray diffraction
• Serial X-ray crystallography
• Time resolved X-ray crystallography
• Neutron diffraction
• Electron diffraction of nano-crystals
with the aim of solving de novo structures, searching ligands, elucidating reaction mechanisms...
This 1-week course will combine theoretical lectures and practicals on ESRF beamlines and other EPN instruments. It is dedicated to researchers (advanced PhD, PostDoc, Scientist) interested in macromolecular structural studies at atomic resolution using crystallographic approaches.
The course will take place from November 05 to November 09, 2018 at the EPN campus, Grenoble, France. To apply, please, send a short CV (1 page max.) and a motivation letter to marta.elzo-aizarna@ibs.fr before September 15, 2018.
The registration is free and includes accommodation and meals on the EPN campus. Selected applicants will be notified by e-mail on September 30, 2018. Participants will have to pay for their travel expenses. More details about the workshop can be found on the dedicated web site.
ADTB is funded by IBS, EMBL, ESRF, CBS, FRISBI, CRISTECH, AFC, UGA, Grenoble INP, CNRS, CEA

2nd Annual day dedicated to Ion Channels - October 04, 2018 - Grenoble

The 2nd scientific day dedicated to ion channels aims to bring together the Grenoble community studying these membrane proteins in order to stimulate exchanges and discussions. This event covers various aspects such as bioengineering of channels, structure-function studies, pharmacology, physiopathological roles...

In addition to 6 speakers (including 3 IBS researchers : Christophe Moreau, Hugues Nury and Beatrice Schaack), slots are reserved for spontaneous applications. Thanks to people who would like to present their activity in connection with ion channels to send an email with the title of the topo to A. Bouron (BIG/LCBM), organizer of this day (alexandre.bouron(at)cea.fr).

Location : Entry seminar room, CEA - 17 rue des Martyrs - Grenoble (no need for a badge)

"Neutrons and Biology" School - 16 to 19 september 2018 - Carqueiranne

The 2018 edition of the thematic School of the Neutron French Society (SFN) will be dedicated to "Neutrons and Biology" and will take place in Carqueiranne (France) on September 16-19, 2018.
The School "Neutrons and Biology" will present an overview of the use of neutrons to probe the structure and dynamics of biological systems. Lectures will be presented by researchers from neutron international facilities and from academia and will include basic tutorials on the principles of neutron diffraction and scattering, a description of the neutron sources and instrumentation, as well as seminars on the application of neutron diffraction and scattering to different biological subjects. Students will also be introduced to the reduction, analysis and interpretation of experimental data and to the writing of an experimental proposal.
The target audience includes graduate students, PhD students and postdocs or experienced scientists not familiar with the application of neutrons to biology.
The list of topics includes :
 Neutron diffraction/crystallography
 Neutron reflectometry
 Elastic, quasielastic and inelastic neutron scattering
 Small angle neutron scattering
 Integrated approaches
 Industrial applications

All details can be found on the school website.
The deadline for the registration is the 30th June 2018.

This school, promoted by the French Neutron Society (SFN), is co-organized by IBS, ILL & LLB. G. Schirò (IBS/DYNAMOP) is part of the Organizing Committee and will give a lecture.

ESONN 2018 - August 26th to September 15th 2018 - Grenoble

From 2004, ESONN is a three-week course aimed at providing training for graduate students, postdoctoral and junior scientists from universities and laboratories, all around the world, in the field of Nanosciences and Nanotechnologies. The academic and practical courses will cover aspects such as the elaboration, characterization and functionalities of nano-objects.The program emphasizes the role of laboratory courses (half of the program is devoted to practical work).
IBS scientists are involved in practical courses for the biological session :

• "Proteins and nanoparticle assemblies and interactions by AUC and SEC/MALS" by Christine Ebel & Aline Le Roy (IBS/M&P) - PDF
• "Cell imaging analysis of protein interactions and dynamics in living cells" by Françoise Lacroix, Joanna Timmins & Jean‐Philippe Kleman (IBS/IRPAS) - PDF
• "Study of biomolecular interactions by surface plasmon resonance biosensor analysis (BIAcore technology)" by Jean-Baptiste Resiser (IBS/IRPAS) - PDF
• " Cryo-Electron Microscopy : sample preparation and visualization using a Polara and a Krios electron microscope both equipped with a direct electron detector" by Guy Schoehn and Isai Kandiah, IBS and ESRF - PDF
  Information & registration on ESONN web site.

2nd FeSBioNet Training School "Multidisciplinary approach for the understanding of FeS protein biogenesis" - September 10-14, 2018 - Grenoble

As part of the European Cost CA15133, the ’Laboratoire Chimie et Biologie des Métaux’ organized a practical training school to provide an overview of the main challenges encountered in studying the processes of FeS aggregate biogenesis. This practical school offered unique expertise in structural approaches to the Fe-S clusters study.
Several IBS laboratories were involved in this school through :

• conferences by Juan C. Fontecilla-Camps (IBS/METALLO) and Irina Gutsche (IBS/MEM)
• practical sessions organized by Juan C. Fontecilla-Camps, Anne Volbeda, Xavier Vernède, Lydie Martin and Claudine Darnault (metalloprotein crystallography) and G. Schoehn and Ambroise Desfosses (electron microscopy)

Workshop "Use of Electron Microscopy for the study of bacteriophages" - 12 and 13 September 2018 - IBS

In the frame of the Phages.fr Network, Cécile Breyton (IBS/M&P) organized a workshop on the use of Electron Microscopy for the study of bacteriophages (Program). About twenty participants from all over France gathered for courses and practical work on the electron microscopy platform.

Summer School Glyco - July 02 to 04, 2018 - Grenoble

Affiche/Flyer

The 2018 edition of the Structural Glycosciences Summer School will be held from 2nd to 4 of July at IBS on EPN campus and at CERMAV on UGA campus. The Summer School is co-organized by the Glyco@Alps CDP project from Idex UGA and the EEC network PhD4GlycoDrug (F. Fieschi & C. Laguri, IBS and A.Imberty & A. Varrot, CERMAV).
Glycoscience is a rapidly expanding and exciting field that is relevant to many areas of chemistry, biology and medicine. Structures of Glycan or Protein/Glycans complexes are of direct importance since they are key structural elements in cell and in signalling events on their surface. The workshop will introduce and train young scientists, from a chemistry or biology background, in the most up-to-date approaches for determining the structural and dynamic properties of carbohydrates, glycan binding receptors, and analysis of their complexes. Young researchers from Grenoble and from whole Europe will have conferences from international speakers, will participle to hands-on in modeling and experimental techniques, and will visit the beam lines at ERSF.
To know more. Deadline for registration : April 20, 2018.

Mini-symposium on glycoinfection - June 25, 2018 - IBS

Glyco@Alps and Immunoshape organize a mini-symposium on glycoinfection : sugar, pathogen & infection.
The event will take place on June 25 at 2 pm at IBS, seminar room.
To know more about program and registration, please read the dedicated web site.

First PSB school in Cryo-Electron Microscopy - 14th-20th June, 2018 - EPN Campus

The course will consist of morning lectures and afternoon practical sessions focusing mainly on single particle analysis, but some other cryo-electron microscopy techniques will also be introduced in some of the morning lectures. The morning lectures will be open to everyone (no registration required but access to EPN campus is required). Registration is required for practicals, which are limited to a MAXIMUM of 20 PARTICIPANTS and priority will be give to students and postdocs. Registration deadline 25th May, 2018. For further details on the programme and registration, please visit our website.

Half-day for Rhone-Alpine users of SPR and BLI systems - 14 June - IBS

This event is organized in collaboration with DCM/I2BM and ICMG/PCI of the University Grenoble-Alpes.
Attendants are invited to present their work during this half-day. Please contact the scientific coordinators (jean-baptiste.reiser[at]ibs.fr or jerome.dejeu[at]univ-grenoble-alpes.fr) before 1 June with a short summary.

PSB Spotlight on Membrane Proteins - Wednesday 13 June 2018 - EPN Campus

The purpose of this meeting is to inform students and researchers on the methods and tools available for the study of membrane proteins. Two IBS speakers (Paul Schanda and Hugues Nury), as well as Vadim Cherezov (SCRIPPS, USA) and Selma Maric (U. Malmö, Sweden), will present their work in the Chadwick amphitheatre in the morning. And two practical sessions are also planned in the afternoon, on crystallization by cubic lipid phase and on data collection at ESRF using the "Mesh and Collect" method. To know more.

RéNaFoBIS School, June 01 to 08 2018, Oléron

This school, organized by RéNaFoBIS (Réseau National de Formation en Biologie Structurale Intégrative), aims at providing training for graduate students in the field of Integrative Structural biology.
D. Housset (IBS/IRAPS group) is co-organizer. IBS scientists (Leandro Estrozi, Jean-Luc Ferrer and Dominique Housset) will give lectures and tutorials. To know more (in french only).

IBS Scientific Day - June 07, 2018 - Saint Martin d’Hères

On June 07, nearly 200 participants gathered on the university campus for the IBS annual Scientific Day. Researchers and students were able to present their research projects through posters and oral presentations to peers. On this occasion, the Best Poster Award was given to Kevin Floch (VIC Group) for his work on ’Cell shape and nucleoid dynamics during Deinococcus radiodurans cell cycle’.
The event, organized voluntarily far from the laboratory, is an excellent opportunity to learn and share topics that are studied at the IBS and share a moment of privileged exchanges.

Les Houches - TSRC Workshop on Protein Dynamics - 27 May - 01 June 2018 - Les Houches, France

This international workshop is a forum for presenting and discussing results from state-of-the-art experimental approaches (including optical spectroscopy, NMR spectroscopy, X-ray crystallography, XFELs, electron microscopy, atomic-force microscopy and scattering methods), and theoretical and computational methods for studying protein dynamics.

In Les Houches, about 30 invited speakers gave oral presentations that comprise a pedagogic introduction to the methodology employed, followed by applications from their own work. Each 30-minute presentation was followed by 15 minutes of discussion. In addition to the 30 invited speakers, there was space for 30 student/postdoctoral participants to present posters. The interdisciplinarity and format with a small number of participants (60), as well as the venue created an excellent atmosphere of exchange of ideas and knowledge sharing, which was enthusiastically welcomed by speakers, researchers and students from 5 continents.

The Les Houches – TSRC Protein Dynamics Workshop complements the long-standing TSRC Protein Dynamics Workshop, held every other year in the odd calendar years at the Telluride Science Research Center in Telluride, Colorado. The workshop will be organized in Les Houches again in 2020. To know more, please consult the Workshop webpage

Organizers :
Paul Schanda ((Institut de Biologie Structurale, Grenoble, France)
Martin Weik (Institut de Biologie Structurale, Grenoble, France)
Matthias Heyden (Max-Planck Institute, Mühlheim an der Ruhr, Germany)
James Fraser (UCSF, USA)

Characterisation of macromolecular complexes by integrative structural biology - 12 to 19 May 2018 - EPN Campus

This EMBO Practical Course aims to teach participants how to integrate structural biology approaches to expedite characterization of large macromolecular complexes from the atomic to cellular scale. Lectures and practical sessions will explain the techniques used to produce, purify, reconstitute and characterize multi-subunit protein and protein/nucleic acid complexes for structural analysis.
This Practical Course is co-organized by Marco Marcia (EMBL), Montse Soler López (ESRF), Daniele DeSanctis (ESRF), Estelle Mossou (ILL) & Carlo Petosa (IBS).
To know more

Workshop : Determination of protein structure by NMR - 23-27 april 2018 - IBS, Grenoble

The biomolecular NMR group of IBS (Grenoble), the Structural Chemistry and Biology Laboratory of ICSN (Gif-sur-Yvette) and the Biological Polymer Structure and Dynamics by Nuclear Magnetic Resonance team of IGBMC (Strasbourg) are organizing an advanced practical training course entitled "Determination of Protein Structure by NMR". This training will take place in Grenoble from 23 to 27 April 2018. It follows the training courses organized by these laboratories every year since 2009.

The objective of this training will be to provide participants with the tools necessary for the structural study of proteins by NMR. This training is primarily aimed at PhD students who will need these techniques during their work but also engineers, post-docs and academic or industrial researchers. We will present modern techniques for assigning resonances of 15N and 13C labeled proteins, acquisition and analysis of NOEs constraints and residual dipolar couplings, as well as modeling tools.

Emphasis will be put on practical aspects of the spectrometer (maximum three participants per spectrometer) on the IBS NMR platform and in front of the workstations. The practical aspects of this training will be complemented by seminars presenting the latest developments in structural attribution and determination, dynamic characterization of proteins, study of high molecular weight proteins and study of intrinsically disordered proteins.

The training will be given in French but with French and English speaking practice groups. This training will be free of charge, participants will be responsible for travel, accommodation and evening meals. Several scholarships covering accommodation will be allocated.

Registration form HERE
Registration deadline : 15th march 2018.

The number of places is limited to 20. To register, please send the form by email, accompanied by a short CV (max 1 page) to ibs.evt.nmrschool@lists.ibs.eu. If you can benefit from vocational training, please contact us.

HERCULES 2018 - European School - 25 February-30 March, 2018

HERCULES is a European course for PhD students and young researchers using Neutrons and Synchrotron Radiation for applications in Biology, Chemistry, Physics, Hard & Soft Condensed Matter.

The 1-month school includes lectures (60%), hands-on practicals and tutorials at partner institutes (Elettra and FERMI in Trieste, Italy, ESRF, ILL in Grenoble, Soleil and LLB in Paris-Saclay, PSI in Villigen, Switzerland) and Grenoble Laboratories (CEA, CNRS, EMBL, IBS).

The school includes a common part and two parallel sessions :
 Biomolecular, soft condensed matter structure & dynamics
 Physics and chemistry of condensed matter

F.Gabel (IBS/ELMA) is co-director of the HERCULES school for the biology session and many IBS scientists give lectures and tutorials.

For details, please have a look on the website of the course. Deadline for application 25 October 2017

XXe Journées Francophones de Virologie 2018 - 22-23 March 2018 - Paris

The XXth edition of the JFV organized by the French Society of Virology will take place from 22 to 23 March 2018 at the Institut PASTEUR in Paris. It provides an opportunity for thesis students, post-doctoral students and young researchers to present their research work in the field of fundamental virology (animal or plant) or medical virology. The themes discussed provide a global vision of advances in infectiology.
Rob Ruigrok and Thibault Crepin (IBS/Viral Replication Machines Group) are members of the Organizing Committee.
Subscribe now !

Les Houches School of Physics : Fluorescence markers for advanced microscopy, March 18 - 23, 2018

A winter training dedicated to Fluorescence Markers for Advanced Microscopy will take place at the Ecole des Houches, France, 18-23 March 2018. This biophysics school aims at training students and young researchers to master fluorescent markers used in advanced fluorescence bioimaging : their diversity, how they actually work and what are their current development.
Applications for registration are open. Deadline is December 15th. Registration
Organising committee : Dominique Bourgeois (Institut de Biologie Structurale, Grenoble), Ulrike Endesfelder (MPI Marburg), Emmanuel Margeat (Centre de Biochimie Structurale, Montpellier), Fabienne Mérola (Laboratoire de Chimie Physique, Orsay)

3rd Annual Users Meeting of iNEXT, 19-21 March 2018, EPN Campus

The 3rd Annual Users Meeting of iNEXT will take place at the Grenoble EPN campus from 19 - 21 March 2018. This meeting, co-organized by IBS, ESRF, and EMBL, is intended to bring together both, iNEXT users to exchange on recent scientific advances made in the field of structural biology.
Scientific presentations by invited keynote speakers and selected abstract presenters will cover a broad range of topics and experimental techniques (X_rays, cryo EM, NMR, …).
Participation to the meeting is free of charge, but registration is mandatory.
More information on the event and on-line registration can be found on the dedicated website.

MXIS 2017 : Practical course on in-plate crystallography, with special focus on ligand screening, 29 Nov. - 1 Dec., EPN Campus

The MXIS training course was dedicated to in situ protein crystallography, with a special emphasis on ligand screening. This workshop was organized in two parts, each one lasting for 3 days. It includes :

• Part 1 (Montpellier) : full lectures at the “Centre de Biochimie Structurale” followed by practicals. Topics : plate pre-coating for “Dry” co-crystallization, in situ screening on a lab source).
• Part 2 (Grenoble) : full lectures at the “Institut de Biologie Structurale” and practical sessions at the ESRF, on beamlines FIP-BM30A and ID30B. Full classes will be in day 1 while practical sessions will be organized in subgroups, from day 2 to day 3. Topics : in situ diffraction for crystal screening and structure resolution, in situ data processing.

Possibility was given to participants to practice on their own samples. Applicants were be required to submit a short CV and a motivation letter to Jean-Luc Ferrer.

8 participants from 7 different countries attended this workshop, organized by IBS, ESRF , EMBL (Grenoble) and CBS (Montpellier). MXIS-2017 was made possible thanks to financial support from IBS, EMBL, and the FRISBI program.
More information on the dedicated website.

2nd meetings of the GDR GAG, 09-10 October 2017, IBS

The next 9th and 10th of October, the 2nd meetings of the GDR GAG will be held at the IBS. The GDR GAG gathers 14 French teams in the fields of chemistry, biology and methodological approaches, which study the complex polysaccharides of the glycosaminoglycan family. Major area of research within the GDR focus on GAG biosynthesis, structure and functions of, as well as on possible therapeutic applications based on GAG mimetics.
Meeting on the 9th of October will be restricted to GDR member, but the scientific day on the 10th is open to all. The program and registration details can be found on the
GDR website.
Contact : Romain Vivès

ESONN 2017 - August 27th to September 16th 2017 - Grenoble

From 2004, ESONN is a three-week course aimed at providing training for graduate students, postdoctoral and junior scientists from universities and laboratories, all around the world, in the field of Nanosciences and Nanotechnologies. The academic and practical courses will cover aspects such as the elaboration, characterization and functionalities of nano-objects.The program emphasizes the role of laboratory courses (half of the program is devoted to practical work).

IBS scientists are involved in practical courses for the biological session :

• "Proteins and nanoparticle assemblies and interactions by AUC and SEC/MALS" by Christine Ebel & Aline Le Roy (IBS/M&P) - PDF
• "Cell imaging analysis of protein interactions and dynamics in living cells" by Françoise Lacroix, Rose-Laure Revel-Goyet & Jean‐Philippe Kleman (IBS/IRPAS) - PDF
• "Study of biomolecular interactions by surface plasmon resonance biosensor analysis (BIAcore technology)" by Jean-Baptiste Resiser (IBS/IRPAS) - PDF

Information & registration (until May 17th) on ESONN web site.

9th AFMBioMed Summer School - August 21st to 25th, 2017 - IBS

The School offers an introduction to Atomic Force Microscopy in Life Sciences and Medicine for Ph.D student, post-docs, scientists, core facility technicians and engineers. Lectures in the morning are complemented by hands-on experiments in the afternoon usually supervised by the lecturers. There are about 20 places for students doing hands-on experiments. Participants are encouraged to send a CV and a motivation letter to the organizers. AFM beginners are welcome.
This school is co-organized by the Pasteur Institute at Lille and ILL. Registration deadline : June 15th, 2017. To know more.
Contact : Jean-Luc Pellequer

Cryo-EM Symposium, 6-7 July 2017, EPN campus

On July 6th and 7th, our campus hosted a unique CRYO-EM Symposium in the framework of the newly established cryo-EM platform. The new facility is open to the user community based on peer-review of scientific merit and technical feasibility. Scientists from ESRF, IBS and EMBLsupport user operation.

The aims of this conference were to promote the exciting opportunities in structural biology opened by the advances in EM, to introduce the Titan Krios microscope that just arrived at the ESRF, and to describe the newly established cryo-EM facility at the EPN campus to the international user community. Check out the programme here.
This symposium brought together 170 registered leading experts, researchers and representatives of industrial partners that presented the latest developments in cryo-EM as well as outstanding research in structural biology.
The Symposium was live-streamed through the ESRF YouTube channel and viewers commented in real-time during the presentations.

It was organized by all institutes of the EPN campus (ESRF, EMBL, IBS and ILL), financially supported by the organizations PSB, CEA, GRAL, FRISBI, UGA and sponsored by Thermo Fisher, Gatan, Molecular Dimensions, Mitegen and Quantifoil
Organising committee : Stephen Cusack (EMBL), Trevor Forsyth (ILL/Keele), Wojciech Galej (EMBL), Gordon Leonard (ESRF), Marco Marcia (EMBL), Christoph Mueller-Dieckmann (ESRF), Hugues Nury (IBS), Guy Schoehn (IBS), Montserrat Soler-Lopez (ESRF), Jean Susini (ESRF) and Winfried Weissenhorn (IBS).
Grégory Effantin and Irina Gutsche gave a presentation during this symposium.

RéNaFoBIS School, June 16-23 2017, Oléron

This school, organized by RéNaFoBIS (Réseau National de Formation en Biologie Structurale Intégrative), aims at providing training for graduate students in the field of Integrative Structural biology.
D. Housset (IBS/IRAPS group) is co-organizer. IBS scientists will give lectures and tutorials (Catehrine Bougault, Jean-Luc Ferrer, Dominique Housset and Hélène Mallet)
To know more

FluoDay 2017 - Tuesay, June 20th, 2017 - IBS

Plaquette/flyer

The IBS will host the FluoDay 2017 on Tuesday, June 20th from 8:30 until 17:00. The objective of this event is to bring together experienced and non-experienced users of fluorescence optical microscopy in Grenoble and to present the activities of the microscopy platforms, including the biological projects that have benefited from them. A round table will also be organised to discuss issues and problems commonly encountered by users of fluorescence microscopy, and the lunch break will provide the opportunity to get in touch directly with the specialists from the platforms. The meeting is open to all, and is aimed at microscopists wishing to explore new techniques but also at scientists from other fields planning to use fluorescence microscopy in the near future.

Free and mandatory registration through the website : http://fluoday2017.strikingly.com

Organising committee : Cecile Morlot, Joanna Timmins, Virgile Adam, Joël Beaudouin from IBS, Laetitia Kurzawa from CEA/BIG and Olivier Destaing from IAB.

IBS Scientifc Day, June 16, 2017

204 participants, including colleagues from EMBL Grenoble, gathered in Saint Martin d’Hères on June 16, 2017 for the 10th edition of the IBS scientific day.
This event allowed groups who hadn’t presented themselves in 2016 to promote their research activities and the conference included two platforms presentations.
On the occasion of the flash/posters sessions, 20 papers were presented by 2nd year doctoral students (and some post-doctoral fellows who wished it), and Rana El Masri (IBS/SAGAG) was awarded the prize for best poster.
This annual day is an invitation to exchange and share experiences.

Biacore user meeting, May 30 2017, IBS

This meeting, organized by IBS and GE Healthcare Life Sciences, will gather occasional or frequent users of Biacore systems and more generally of SPR systems for the characterization of molecular interactions.
It will be hold in IBS on May 30, from 2 to 4pm and include short scientific presentations and a presentation of the SPR platform (program). It’s an opportunity to share best practice, knowledge, experiences.
This meeting is open to anyone interested in protein /protein or protein/ligand interactions.
Registration by email to Jean-Baptiste Reiser.

NMR and biological interactions Training - ICSN Gif-sur-Yvette - Avril 3-7, 2017

The aim of this training is to provide participants with the necessary tools for the NMR study of interactions of liquids involving proteins (protein-biomacromolecule and protein-ligand complexes). The training is co-organized by IBS (Grenoble), IGBMC (Strasbourg) and ICSN (Gif-sur-Yvette).
To know more

Organization  :
IBS : Beate Bersch, Jérôme Boisbouvier, Catherine Bougault, Bernhard Brutscher, Pierre Gans, Adrien Favier, Jean-Pierre Simorre, Dominique Marion
ICSN : Nadine Assrir, François Bontems, Eric Guittet, Carine van Heijenoort, Ewen Lescop, Nelly Morellet, Christina Sizun
IGBMC : Bruno Kieffer, Yves Nominé

2017 Hercules course - February 27 to March 30, 2017 - Grenoble

Co organizd by the Université Grenoble Alpes (UGA) and Grenoble INP, this 4-week school is a yearly event, established in 1991. It provides training for students, postdoctoral and senior scientists from European and non-European universities and laboratories, in the field of Neutron and Synchrotron Radiation for condensed matter studies (Biology, Chemistry, Physics, Materials Science, Geosciences, Industrial applications).
It includes lectures, practicals, tutorials, and visits of Large Facilities.
The school has a session dedicated to biology covering mainly X-ray and neutron scattering but also some complementary techniques.

F.Gabel (IBS/ELMA) is co-director of the HERCULES school for the biology session and many IBS scientists give lectures (Elisabetta Boeri-Erba, Dominique Bourgeois, Frank Gabel & Monika Spano) and tutorials (E. Girard, M. Pirocchi & A.Royant).

For details, please have a look on the website of the course.

Les Houches Winter school - Biology at different scales : an interplay between physics and biology- March 13-24, 2017

The school is aimed for PhD students and early-stage researchers. Participants learn how a biological problem can be tackled using an integrated approach, going from atomic resolution to the level of a whole organism level. The school also aims at showing how physics can contribute to model biological processes. Several topics are covered : cell and tissue morphogenesis, role of membranes at mesocopic and molecular scales : remodeling and transport processes, concepts and methods from physics applied to biology, state-of-the-art experimental approaches, links between cellular and structural biology. The concepts and methods was illustrated with two research fields, Plant morphogenesis from gene to flowers, and Exocytosis and morphology of the synapse.
This school, co-organized by R. Jahn, H. Nury, F. Parcy, E. Pebay-Peyroula, took place near Chamonix (Les Houches, France) in March 2017.
To know more

Advances Isotopic Labeling Methods for Integrated Structural Biology International Workshop (AILM 2017) - March 6th to 9 th, 2017 - EPN Campus Grenoble

The second AILM workshop will focus on the development of isotopic labelling techniques and their application to the study of biomolecular structure and dynamics. Conference sessions covered developments in isotopic labelling strategies for NMR spectroscopy, mass spectrometry, neutron scattering and diffraction, as well as methodological approaches, such as co-expression, segmental labelling, specific labelling, labelling with paramagnetic tags, and sample production in vitro or in eukaryotic cells. The program also included elegant examples of the application of these methods to challenging systems such as high molecular weight proteins and nucleic acids complexes or direct studies of biomacromolecules in cells or tissues.
Information and registration
Organizers : Jerome Boisbouvier (IBS/NMR), Bruno Kieffer (IGBMC - Strasbourg), Michael Plevin (University of York - UK) and Carine Tisné (IBPC – Paris)

PSB Spotlight on NMR PSB Spotlight on NMR spectroscopy, Thursday 16 February 2017, IBS

The aim of this event is to inform PSB students and researchers on how to exploit this technique to advance their research projects.

• Program
• Practical session
• Registration (deadline February 10, 2017)
  Registration is free, but in order to simplify the organisation please indicate if you will attend the talks in the morning and if you would like to participate to the tutorial in the afternoon.

MXIS 2016 Part II : Practical course on in-plate crystallography and in situ diffraction, November 30-December 02, 2016, IBS

MXIS training course is dedicated to in situ protein crystallography (ligand coating, crystallogenesis, in situ diffraction for crystal screening and structure resolution, in situ data processing). This 2-part workshop includes full lectures and practical sessions :

Part 1 : 7 - 9 Nov., Montpellier. Lectures at the CBS. Pratical sessions at the CBS on "dry-coating" and crystallization assays.

Part 2 : 30 Nov. - 2 Dec., Grenoble. Lectures at the IBS. Crystallization assays at the EMBL. Practicals on beamlines FIP-BM30A and ID30B at the ESRF.

Program

Possibility is given to participants to practice on their own samples.

The workshop is limited to 8 participants, with no registration fee.If interested, fill out the form and send a short CV to Jean-Luc Ferrer or Gilles Labesse by September 30th.

This workshop is organized by the CBS (gilles.labesse (at) cbs.cnrs.fr), the IBS (jean-luc.ferrer (at) ibs.fr), the EMBL-Grenoble and the ESRF (andrewmc (at) embl-grenoble.fr ; christoph.mueller_dieckmann (at) esrf.fr ; marquez (at) embl-grenoble.fr).

Cristech 2016, october 10-12, 2016 (Autrans)

The CRISTECH network (Mission for the Interdisciplinarity - CNRS) organizes every two years, days devoted to technology and methods in general and multidisciplinary field of crystal growth and characterization of single crystals.
The ‘CRISTECH 2016’ days will be held from 10 to 12 October 2016 in Autrans (Isère) in the resort "The Escandille ".
Monika Spano (IBS/GSY) will animate the 7th session (Biomaterials). The list of sessions and invited speakers is available on the website of Cristech].
Pre-register now by following this link.

100 years of heparin : the success of a carbohydrate, 10 octobre, Paris

A scientific meeting, organized by IBS/SAGAG group, will be hold in Paris on October 10, under the auspices of Aviesan, to celebrate the 100th anniversary of the discovery of heparin. This conference will bring together glycosaminoglycans specialists and non-specialists working on biological systems in which these molecules are involved. The detailed program can be found on https://bmsv2016.sciencesconf.org/. This event will be followed by the first meeting of the of the French “GDR – Gagoscience” (https://gagosciences.ibs.fr/). Registration is free but compulsory before 3th of October 2016 (abstract submission before 27th September 2016).

IBS Scientific Day, September 16, 2016

The IBS 2016 Scientific Day takes place on the campus of Saint Martin d’Hères on September16th.
It provides opportunities for students to work on presentation skills as well as encourage IBS scientists to interact. All staff is encouraged to attend.

16th European Microscopy Congress (EMC2016), August 28- September 2, 2016, Lyon

The EMC is held every 4 years under the auspices of the EMS. This European Conference is covering all kinds of microscopy, from optics to electronic, both in matter or life sciences. Guy Schoehn (IBS / MEM), chairman of the SFMU, is among the organizers of this conference that hosts more than 2,000 participants. As part of this conference, the IBS electron microscopy platform organizes a day of training in cryo-electron microscopy on August 26. To know more : http://www.emc2016.fr.

Workshop ’Structural Glycoscience’, June 28-30, 2016, Grenoble

Programme & inscription/ Workshop program & registration

Glycoscience is a rapidly expanding and exciting field that is relevant to many areas of chemistry, biology and medicine. Structures of Glycan or Protein/Glycans complexes are of direct importance since they are key structural elements in cell and in signalling events on their surface.
The workshop will introduce and train young scientists, from a chemistry or biology
background, in the most up-to-date approaches for determining the structural and dynamic properties of carbohydrates, glycan binding receptors, and analysis of their complexes.
This workshop will be validated by 2 credits by the EDCSV doctoral school.
Deadline for registration : 29 April 2016
Contact & information : gwendoline.vallez@ujf-grenoble.fr

Rhone-Alpes Very High Fields NMR User Meeting, June 16,2016, Lyon

The NMR teams of the Institut de Biologie Structurale (IBS), Institut des Sciences Analytiques (ISA, Institut de Biologie des Protéines (IBCP) and Institut de Nanosciences et Cryogénie (INAC), under the aegis of the IR-RMN-THC national federation, organize a day dedicated to Very High Fields NMR and Industrial questions.
This event aims to provide a high-level forum between physicists, chemists and biologists working in industry and in academic laboratories, allowing university researchers to be informed about current challenges in the use of NMR in an industrial context and in parallel to present to industrial researchers the latest developments about very high magnetic field and the instrumentation and techniques available in a handful of NMR platforms.

Affiche/Flyer

Several topics will be discussed during this day : Life sciences and health ; Metabolism, diagnosis, prevention and toxicology ; Catalysis, sustainable development and energy ; Polymer materials ; Products and scientific instrumentation.
Registration is free but mandatory. Further information can be found here.

Archaea Conference, May 25-27, 2016, IBS

This event, organized by the Extremophiles and Large Molecular Assemblies Group (IBS/ELMA), brings together microbiologists, computer scientists, biochemists, biophysicists and chemists, (about 80 people) of the French scientific community to discuss about the role of Archaea. The following topics will be discussed :

• understand the fundamental molecular mechanisms of these organisms and their viruses,
• study their adaptation to extreme conditions to get some information about the limits of life and its capacity for expansion in the universe
• Biotechnologies of extremophiles
  Registration

Three plenary conferences are opened to all PSB members :

• Seminar May 25, 2pm
• Seminar May 26, 11am
• Seminar May 27, 11 am

EMBO Course on Macromolecular Complexes, 21-27 May, Grenoble

The course consists of lectures (open to local and PSB scientists) and practicals (reserved for EMBO course students).
Lectures take place at the ILL Chadwick amphitheatre (Mon-Fri) or the EMBL seminar room (Sat-Sun and Mon at 18h).
This course is co-organised by M. Marcia (EMBL), T. Forsyth (ILL), M. Soler-López (ESRF), D. DeSanctis (ESRF), D. Hart (IBS) et C. Petosa (IBS).
To know more

RéNaFoBIS School, May 20-27, 2016, Oléron

This school, organized by RéNaFoBIS (Réseau National de Formation en Biologie Structurale Intégrative), aims at providing training for graduate students in the field of Integrative Structural biology.
D. Housset (IBS/IRAPS group) is co-organizer.
To know more (registration from end of january 2016)

2016 Hercules course

Co organizd by the Université Joseph Fourier (UJF) and Grenoble INP, this 4-week school is a yearly event, established in 1991. It provides training for students, postdoctoral and senior scientists from European and non-European universities and laboratories, in the field of Neutron and Synchrotron Radiation for condensed matter studies (Biology, Chemistry, Physics, Materials Science, Geosciences, Industrial applications).
It includes lectures, practicals, tutorials, and visits of Large Facilities.
The school has a session dedicated to biology covering mainly X-ray and neutron scattering but also some complementary techniques.

Two IBS researchers are part of the organization : F.Gabel as co-director of the HERCULES school for the biology session and J. Peters in the organizing committee. Many IBS scientists will give lectures and tutorials (Elisabetta Boeri-Erba, Dominique Bourgeois, Frank Gabel et Monika Spano).

The registration is until October 31, 2015.

For details, please have a look on the website of the course.

7th AFMBioMed conference, April 11-15, 2016, Porto

AFM BioMed Conference is dedicated to life sciences and nanomedicine applications and investigate how Atomic Force Microscopy (AFM) solves relevant biological bottlenecks and provides innovative solutions for healthcare.
Biologists, biophysicists and medical scientists with research interest in cell, cell interactions, single-molecule recognition, affinity, functional studies including forces, high resolution imaging and more, can attend.
Abstract submission : candidates can select their preference for an oral or poster presentation. About 40 oral presentation slots will be selected not only based on scientific merit but also on the ability to attract the interest of a broad audience. The conference will include 2 poster sessions as part of the program. The call for abstracts will be open until 1st February 2016.
Jean-Luc Pellequer (IBS/MEM) co-created this conference and is a permanent member of the scientific committee.
Registration form

Les Houches-TSRC Workshop on Protein Dynamics- 3-8 April 2016, Les Houches

This workshop is a forum for presenting, teaching and discussing results from the application of state-of-the-art experimental (including, but not limited to, optical spectroscopy, NMR spectroscopy, X-ray crystallography, XFELs, electron microscopy, AFM and scattering methods), and theoretical and computational approaches to studying protein dynamics.
About 30 invited speakers will give oral presentations that comprise a pedagogic introduction to the methodology employed, followed by applications from their own work. Each 30-minute presentation will be followed by 15 minutes of discussion. In addition to the 30 invited speakers, there will be space for 30 student/postdoctoral participants that can present posters. To know more, please consult the Workshop website.
Register at TSRC before March 10th, 2016. The 30 non-speaker slots will be filled on a first-come first-served basis.
It is organized by Paul Schanda and Martin Weik (IBS, Grenoble), Arwen Pearson (CFEL, Hamburg), Douglas Tobias (UC Irvine).

Rhone-Alpes Microbial Interactions user meeting, March 24, 2016, IBS

La prochaine rencontre du Groupe Régional de Recherche En Microbiologie des Interactions (G-RREMI), qui réunit des bactériologistes lyonnais et grenoblois, aura lieu le 24 mars 2016 à l’IBS. La première partie de la rencontre aura pour thème ‘Les apports des techniques de microscopie à l’étude des interactions procaryotes-eucaryotes’ ; la seconde partie est ouverte à tous les champs disciplinaires couverts par notre groupe.Nos conférenciers invités sont Irina Gutsche (groupe ‘Methods and Electron Microscopy’, IBS, Grenoble) et Philippe Normand (groupe ‘Symbiose actinorhizienne’, Ecologie Microbienne, Villeurbanne). Il y aura également des communications orales de 20 minutes et une session poster pendant le temps du repas.
This meeting will be hold in IBS on March 24, from 9am to 5pm and will gather researchers from the Microbial Interactions group), working in Grenoble, Lyon and beyond. The first part of the meeting will be dedicated to the contribution of microscopy techniques to study prokaryotic-eukaryotic interactions. The second part is open to all disciplines covered by the group.
There will be two plenary conferences by Irina Gutsche (groupe ‘Methods and Electron Microscopy’, IBS, Grenoble) and Philippe Normand (groupe ’Symbiose actinorhizienne’, Ecologie Microbienne, Villeurbanne) and some oral communications and a poster session.

GRAL 48h – March 14th and 15th – Autrans

This meeting is open to all GRAL scientists (iRTSV, IBS, UVHCI/EMBL and their Grenoble partners) within the limit of 150 participants. The meeting will consist of short talks and poster presentations concerning the major research themes of the Labex, as well as keynote lectures by three invited speakers.
 This 2-day meeting represents the ideal opportunity to showcase your research, to network with GRAL scientists, and to initiate new collaborations. The Pre-Program has 10 time-slots available for “General presentations on Integrated Structural and Cell Biology”.
 During the meeting we will also organize 2 contests dedicated to the GRAL PhDs and young Post-Docs (less than 3 years after thesis), with prizes awarded for the best Poster and best short (5 min) presentation. More details about the contests here.
 A “speed dating party Structure vs. Cell” will be organized during the evening.
The idea is to favor discussion between people working on structure and people working on cells with the final scope of fostering new collaborations. More details on the organization should be communicated soon.
Participants are expected to attend the meeting throughout the entire 2 days !
For any further information, please contact : celine.guillouet@cea.fr / +33 4 38 78 08 66 / +33 6 98 13 31 30

BACTO-Gre, February 11, 2016, IBS

Affiche/Flyer

This scientific day will bring together scientists from Grenoble for scientific and technical / methodological exchanges around the theme "structural and cellular Bacteriology". This meeting is organized by Ina ATTREE and Sylvie Elsen (BIG), Andrea Dessen and Anne Marie Di Guilmi (IBS). Registration, before January 28, by email to Sylvie Elsen.

Women in Structural Biology Symposium - February 04, 2016 - IBS

This symposium aims to promote the role of women in Structural Biology by inviting renowned researchers to discuss their scientific achievement and address the issue of under-representation of women in leadership positions.
This symposium is organised by Malene Ringkjøbing Jensen (IBS/FDP) and financed by GRAL, FRISBI and CEA.
Program and registration

Rhone-Alpes Biacore user meeting, February 03,2016, IBS

This meeting will gather occasional or frequent users of Biacore systems and more generally of SPR systems for the characterization of molecular interactions.
It will be hold in IBS on February 03, from 2 to 6pm and include short scientific and technical presentations by users and by a GE Healthcare engineer. It’s an opportunity to share best practice, knowledge, experiences.
This meeting is open to anyone interested in protein /protein or protein/ligand interactions.
Registration by email to Jean-Baptiste Reiser or Isabelle Bally, before January 20, 2016.

22nd International Conference on Analytical Ultracentrifugation : From the Centrifuge to the Beamline (AUC2015)

AUC2015 included hands-on workshops given by experts in the field, targeted at students and early-career post-docs through to group leaders wishing to advance their data analysis skills.
The main Symposium that follows featured talks given by leading scientists covering eight contemporary and complementary themes and including twenty-one abstract-selected talks.
Christine EBEL (IBS/M&P group) is member of the International Programme Committee, chair session ’protein-lipid interactions of this conference’.
Details on the website of the conference

NanoMem Workshop, December 07 to 09, IBS & ESRF

In the framework of the Marie Curie ITN NanoMem, a short course on Structural biology of membrane proteins : from expression, to crystallization and serial crystallography took place on Dec 7-9 in Grenoble. This course, organized by Eva Pebay-Peyroula, Stephanie Ravaud, Hugues Nury (IBS) and Manfred Burghammer (ESRF) for Nanonem students could welcome some more students on days 1 & 3. It covered membrane protein expression, purification and stabilization and synchrotron serial crystallography.
Day 2 took place at ESRF on ID-13.
Day 1 and 3 took place in the IBS seminar room.
Applications were be sent to E.Pebay-Peyroula (eva.pebay-peyroula@ibs.fr).

MXIS 2015 : practical course on in-plate crystallography

MXIS training course is dedicated to in situ protein crystallography. This 3-day workshop includes full lectures at the IBS and practical sessions at the ESRF, on beamlines FIP-BM30A and BM14. Full classes are done in day 1 while practical sessions are organized in rotating subgroups from day 2 to day 3 (topics : ligand coating, crystallogenesis, in situ diffraction for crystal screening and structure resolution, in situ data processing). Possibility was given to participants to practice on their own samples.
The workshop was limited to 12 participants, with no registration fee.
Pre-registrations were open at http://workshops.ibs.fr/MXIS-2015. If interested, fill out the form and send a short CV to Jean-Luc Ferrer or Gilles Labesse by September 30th.

9th workshop "Nano and Micro-Environments for Cell Biology "

This 9th NaMiSCeB Workshop brings together students and researchers from Grenoble and beyond working at the interface between physics, engineering, chemistry and biology.
It is organized to conclude Ralf RICHTER’s Chair of Excellence project. Initiated in 2011, “GAG2D” was a remarkably collaborative project which relied on the interdisciplinary expertise of four Grenoble-based laboratories : DCM (which hosts the Chair of Excellence), IBS, LMGP and INAC/SPrAM. Altogether, Ralf RICHTER and his collaborators worked at understanding the role of the extracellular matrix polysaccharides - known as glycosaminoglycans (GAGs) - in the sequestration and presentation of chemokines, the molecules used by cells to communicate between each other.

Organizers : Ralf RICHTER (Chaire d’Excellence), Hugues LORTAT-JACOB (IBS), Roberto Calemczuk (INAC/SPrAM), Catherine PICART (LMGP, Grenoble-INP), Pierre LABBÉ (DCM), Liliane GUERENTE (DCM, UJF).

To know more.

International AFMBioMed summer school 2015

The School offers an introduction to Atomic Force Microscopy in Life Sciences and Medicine for Ph.D student, post-docs, scientists, core facility technicians and engineers. Lectures in the morning are complemented by hands-on experiments in the afternoon usually supervised by the lecturers. There are about 20 places for students doing hands-on experiments. This school is co-organized by the Pasteur Institute at Lille and European Synchrotron Radiation Facility. To know more
Contact : Jean-Luc Pellequer

14th Colloquium of the French society of microscopy

The symposium brought together 310 participants. The scientific program gave an overview of all microscopies in France and presented the latest innovations in the field of Life Sciences and Materials Science.
G.Schoehn, head of the MEM group at IBS, was part of the "Science of Life" scientific committee. To know more : http://www.crhea.cnrs.fr/sfmu2015/

2015 Scientific Day - June 19, 2015

The IBS Scientific Day is held every year. The 8th edition took place on June 19, 2015 at the Centre technique du papier (Saint martin d’hères Campus). The scientific program included scientific presentations by half of the IBS groups, a poster session by all PhD students and post-docs and students in their second year of PhD introduced their poster by a short flash presentation. The poster price was awarded to Romain Berardozzi(DYNAMOP group).

A lunch gathered 190 IBS members in a friendly spirit, suitable for the development of a vibrant and creative community.

RéNaFoBIS School

This school, organized by RéNaFoBIS (Réseau National de Formation en Biologie Structurale Intégrative), aims at providing training for graduate students in the field of Integrative Structural biology. D. Housset (IBS/IRAPS group) was co-organizer. Program

INSTRUCT FRISBI PSB Workshop on Molecular interactions : the complementarity between biophysical methods

The goal of this workshop is to provide theoretical, practical and data analysis training in various modern methods for monitoring and quantifying molecular interactions (SEC-MALLS, UAC, SPR, ITC…).
The course will provide brief introduction to the biophysical concepts and theories, practicals to set experiments up on state-of-art instruments and introduction to data analysis methods.
The workshop is open to all scientists, students, technicians, engineers, and researchers, from academy and industry.
General presentations are open to all scientists, students, technicians, engineers, and researchers, from academy and industry. Practicals are reserved for registred participants.
Organizers : Christine Ebel, Marc Jamin, Nicole Thielens, Florent Bernaudat, Jean-Baptiste Reiser, Aline Le Roy.
Tuteurs : C. Ebel – A. Le Roy – M. Jamin – N. Thielens – J.-B. Reiser – A. Palencia– C. Birck (Strasbourg) – P. Schuck and J. Zhao (Bethesda USA).
Lectures : F. Fieschi - J. Kadlec - T. Forsyth and A. Imberty (Grenoble France)
For more information, please visit the Website of the workshop

EMBO Practical Course "Small Angle Neutron & X-ray Scattering from Proteins in Solution"

This course will cover the use of small angle scattering (SAS) of both neutrons and X-rays for the determination of the structures of biological macromolecules. The aim is to enable the participants to maximise the information gained from the SAS technique in their future experiments.
This course is organized by the PSB partners (ESRF, ILL, EMBL, UVHCI and IBS). Frank Gabel (IBS) is a member of the organizing committeez and will give lectures during the workshop.Information and registration on the dedicated website.

Practical course on NMR

The IBS Biomolecular NMR Spectroscopy Group, the ICSN in Gif sur Yvette and the IGBMC in Strasbourg organize a Workshop entitled “’Protein Structure Determination by NMR”. This course will be given by scientists from Grenoble, Gif and Strasbourg under the supervision of C.Laguri. It will focus on structural determination of proteins by solid-state NMR and will feature hands-on practicals on the NMR spectrometers.

Cryo-Electron Microscopy and 3D Image Processing Pratical Course

Professor Pawel Penczek (director of the "Structural Biology Imaging Center at the University of Texas Health Science Center at Houston") presented the latest techniques of image analysis he has developed and applied to electron microscopy. There were some theoretical courses and practical work (either on model or personal data). This workshop, led by Irina Gutsche (UVHCI) and jointly organized by IBS, UVHCI and EMBL, brought together twenty students. It was hosted by EMBL-Grenoble and benefited from the logistical support of the UVHCI IT team and financial support of Frisbi and Gral.

HERCULES School 2015

Co organizd by the Université Joseph Fourier (UJF) and Grenoble INP, this 4-week school is a yearly event, established in 1991. It provides training for students, postdoctoral and senior scientists from European and non-European universities and laboratories, in the field of Neutron and Synchrotron Radiation for condensed matter studies (Biology, Chemistry, Physics, Materials Science, Geosciences, Industrial applications).

It includes lectures, practicals, tutorials, and visits of Large Facilities.

Two IBS researchers are part of the organization : F.Gabel as co-director of the HERCULES school for the biology session and J. Peters in the organizing committee. Many IBS scientists will give lectures and tutorials (David Cobessi, Adrien Favier, Eric Girard, Monika Spano and Elisabetta Boeri-Erba).

The registration is opened between August 31st and October 15th, 2014.

For details, please have a look on the website of the course.

Meeting for the future users of the neutron bio-crystallography station of the European Spallation Source

A new facility for the use of neutrons began its construction in Lund, Sweden. This source, the European Spallation Source (ESS), will have among others a diffractometer for crystallography of biological macromolecules (NMX diffractometer), whose commissioning is planned around 2023. The expected neutron flux and reduced beam size should allow a real revival of neutron crystallography, raising much of the current limitations, particularly in terms of crystal size and available beam time.

France participates in the ESS project, and as such contributes to the construction of the source and experimental equipment. It could directly contribute to the construction of NMX, in agreement with the expression by the national community of scientific interest. This meeting is dedicated :

• To present this future equipment and the opportunities it will provide to the French community of crystallographers of biological macromolecules ;
• To present the choices related tot the experimental setup, and therefore to gather opinions to refine these choices ;
• To identify needs, to help guide budget decisions.

An introduction to the future NMX station, the program included presentations of results obtained with neutrons, or on the methodology and instrumentation for neutron crystallography, followed by round tables. It was also asked each of the participants a short presentation (1-2 slides) describing their interest in structural biology.

Archaea conference

This event brings together microbiologists, computer scientists, biochemists, biophysicists and chemists, (about 80 people) of the French scientific community to discuss about the role of Archaea, understand the fundamental molecular mechanisms of these organisms and their viruses, their presence in the human microbiome and new technologies associated. 80 people attended these conference.
B.Franzetti (IBS/ELMA group) was part of the scientific committee
Details

International Workshop on Advanced Isotopic Labelling Methods for Integrated Structural Biology (AILM 2015)

The AILM 2015 workshop will focus on the development of isotopic labelling techniques and their application to the study of biomolecular structure and dynamics. Conference sessions will cover developments in isotopic labelling strategies for NMR spectroscopy, mass spectrometry, neutron scattering and diffraction, as well as methodological approaches, such as co-expression, segmental labelling, specific labelling and sample production in vitro or in eukaryotic cells. The programme will also showcase elegant examples of the application of these methods to challenging systems such as membrane proteins, high molecular weight proteins and nucleic acids.

The goal of the workshop is to provide a stimulating and educational forum in which participants can exchange ideas on the latest scientific breakthroughs in the use of stable isotopes in integrated structural biology.

Information & registration

Organizers : Jerome Boisbouvier (IBS/NMR), Bruno Kieffer (IGBMC - Strasbourg), Michael Plevin (University of York - UK) and Carine Tisné (NMR and Cristallography Lab.– Paris)

International Practical School on Advanced Isotopic Labelling Methods for NMR

This School will provide both practical and theoretical training in state-of-the-art isotopic-labelling approaches for NMR studies. The participants will gain hands-on experience in a broad range of labelling methods, including innovative protocols for specific labelling, segmental labelling and in vitro expression of RNA and proteins. Participants will be encouraged to bring their own protein and/or RNA constructs for use in practical demonstrations. The School will provide an environment in which attendants will be able to exchange practical experience on protein labelling with instructors and other participants. This lab-based training course will be held at the IBS in Grenoble, France.

The practical school will be followed by an international workshop on “Advanced Isotopic Labelling Methods for Integrated Structural Biology” organized at IBS from 2nd to 5th February 2015. Trainees enrolled in the practical school will also participate in the AILM2015 workshop, allowing them to attend lectures covering the latest developments and applications of isotopic labelling presented by the leaders in the field.

Information & registration to the School

Symposium on biomolecular dynamics, structure and NMR spectroscopy

This one-day symposium will bring together a range of international and French researchs that aim at understanding biomolecular function at the atomic level. A particular focus will be on studies of protein dynamics and its importance for function.

The presentations will highlight studies of challenging biological objects, such as viral capsids, membrane proteins and large molecular assemblies, and will also demonstrate how new methodological advances in NMR techniques and fluorescent proteins provide new insights into the dynamics/structure/function relationship of these systems.

Registration is free but mandatory. Further information can be found at : https://sites.google.com/site/nmr2014grenoble/

PSB Workshop on “Biomembranes and membrane proteins”

This event gathered together over 70 researchers, PostDocs and PhDs students to exchange information about scientific projects, methodology and instrumentation related to structural and functional studies of membranes and membrane proteins. The aim of the workshop was to provide information about PSB and local activities in order to develop synergy for membrane protein research on the EPN campus.

The workshop was opened by J. Zaccai with a very brief history of membrane research at IBS and EPN campus. E. Bamberg (Director, Department of Biophysical Chemistry of Max-Planck Institute, Frankfurt, Germany) gave an outstanding lecture about microbial rhodopsins and optogenetics. Over 20 speakers from local organizations covered the research field of biomembranes and membrane proteins, including tools and instrumentation.

The discussion at the end of the workshop on the needs for further development in membrane and membrane protein research benefited from the large and dynamic local scientific community. The results of the workshop are highly positive and, with continuing support from the groups involved, we hope the suggestions made will be implement shortly for the benefit of the membranes and membrane proteins scientific community working on the EPN campus.

Organizing committee : Christine EBEL, Valentin GORDELIY, Ekaterina ROUND, Cecile BREYTON, Christophe MOREAU

Local organizations :
The Partnership for Structural Biology (PSB) : The partners are European Molecular Biology Laboratory (EMBL) Grenoble, the European Synchrotron Radiation Facility (ESRF), the Institut Laue Langevin (ILL), the Institut de Biologie Structurale (IBS), which is supported by the French CEA, the French National Centre for Scientific Research (CNRS) and the University of Grenoble (University Joseph Fourier, UJF) and UJF-EMBL-CNRS Unit of Virus Host Cell Interactions (UVHCI).

Contacts : PSBWorkshop2014@ibs.fr

6th Meeting of NMR Research Infrastructures Users

This event brought together users and managers of the national network of flagship NMR facilities providing High-Resolution and High-Field capabilities [TGIR-RMN-THC FR3050 CNRS] to show results, news and to review the operation and user expectations.
Registration

GTBio2014

The Francophone structural biology community gathered in GTBio 2014 from 7 to 10 October 2014 .
This conference, organized by IBS in partnership with the ESRF and under the aegis of the French Association of Crystallography, was held in IBS and ESRF auditoriums on EPN science campus.
Organizing commettee :
Dominique Housset (IBS), Winfried Weissenhorn (UVHCI), Gordon Leonard (ESRF), Eric Girard (IBS), Stéphanie Ravaud (IBS), Beate Bersch (IBS), Guy Schoehn (IBS), Cécile Morlot (IBS), Carlos Contreras-Martel (IBS), Jérôme Dupuy (IBS), Annabelle Varrot (CERMAV)
The conference website is available at the following address : http://gtbio2014.ibs.fr.

16th HERCULES Specialized Course (HSC)

The 16th HERCULES Specialized Course (HSC) on "Non-atomic resolution scattering for biology and soft matter" was held in September in Grenoble.This HERCULES Specialized Course addressed non-crystallographic X-ray and neutron scattering techniques for structural biology and soft matter with a focus on small angle scattering, reflectometry and fibre diffraction.
This course was organized by EMBL, ESRF, IBS and ILL, Frank Gabel (IBS) was part of the organizing committee
More information can be found at the following ESRF website.

ESONN 2014

ESONN is a three-week course aimed at providing training for graduate students, postdoctoral and junior scientists from universities and laboratories, all around the world, in the field of Nanosciences and Nanotechnologies.
The academic and practical courses will give a structured view of the principles involved in the elaboration and in the functioning of nano-object.

IBS scientists are involved in practical courses for the biological session :
 Practical course ESONNBiophysical characterisation of proteins assemblies and interactions by AUC and SEC/MALS by Christine Ebel, Aline Le Roy, IBS
 Cell imaging analysis of protein interactions and dynamics in living cells by Françoise Lacroix, Rose-Laure Revel-Goyet & Jean‐Philippe Kleman, IBS
 Study of biomolecular interactions by surface plasmon resonance biosensor analysis (BIAcore technology) by Nicole Thielens, Institut de Biologie Structurale, CNRS, CEA and UJF.

More information on ESONN web site.

Summer school Les Houches 2014 : Integrated structural cell biology

This summer school provides an exceptional opportunity to develop a broad overview of the state-of-art developments in integrated structural cell biology, to meet in a beautiful environment both senior lecturers who are world leaders in their field, as well as students and early-stage researchers from different countries. Participants learn how a biological problem can be tackled using an integrated approach, going from atomic resolution to a whole organism level.

To know more : http://leshouches2014.eu/

Location : Ecole des Houches
Dates : 07/07/14 to 01/08/14

Contact : Eva Pebay-Peyroula

PSB Blue Symposium

Leading scientists from structural biology and the RNA world presented their exciting results at the 1st PSB Blue Symposium, which was be held on the 27th of June in the IBS seminar room. Confirmed speakers are Chris Dobson (University of Cambridge), Martin Jinek (University of Zurich), Yvonne Jones (University of Oxford), John Mattick (Garvan Institute, Sydney) and Chris Tate (MRC, Cambridge). The Symposium also provides a platform for students and postdocs to present their own research and facilitate scientific exchange.

For more information and program, please visit the website : http://www.embl.fr/training/events/2014/BS14/index.html

Or contact the organizing committee :
T. M. de Oliveira, C. Swale, Q. Jiang, Z. Yang. I. Berger, R. Pillai (EMBL), M. Stelter (IBS)

XVth Rhône Alpes NMR meeting

This year, the NMR Biomolecular laboratory at IBS is organizing the XVth Rhône Alpes NMR meeting which took place on Friday 13th of June at IBS-Grenoble. The aim of this scientific event was to promote contacts among local NMR actors. It was a good opportunity for our students and post-docs to present their results either as oral contributions or posters.

The two invited speakers of this year meeting (JRA 2014) were Christian Bonhomme (Laboratoire de Chimie de la Matière Condensée UPMC - Paris) and Sebastian Hiller (Biozentrum Universität Basel - Switzerland). The remaining scientific program was established on the basis of submitted abstracts among which about 8 of them were selected.

More information is available on the WEB site.

National School of Integrative Structural Biology

RéNaFoBIS (Réseau National de Formation en Biologie Structurale Intégrative) is organizing its first workshop from June 1st until June 6th, 2014 at Oléron (France). This workshop proposed theoritical lectures and practicals on different approaches used in structural biology (X-ray diffraction, NMR, Electron microscopy, cellular and molecular imaging, biophysical investigations of macromolecular interactions). A special focus was made on the integration of these different techniques in order to address biological questions. This workshop was particularly well suited for PhD students and young scientists planning to use these techniques for their scientific projects.
Dominique Housset & Catherine Bougault (IBS researcher) were part of the organizing committee and many IBS scientists gave lectures and tutorials.

website : http://ecolebios2014.sciencesconf.org/
To know more about this event :
http://www.renafobis.fr/ecoles-thematiques/ile-doleron-ecole-nationale-renafobis

Les Houches - TSRC Workshop on Protein Dynamics

This workshop is a forum for presenting, teaching and discussing results from the application of state-of-the-art experimental (including, but not limited to, optical spectroscopy, NMR spectroscopy, THz spectroscopy, X-ray crystallography, XFELs, electron microscopy and scattering methods), and theoretical and computational approaches to studying protein dynamics.

To know more, please consult the Workshop webpage

"Fluorescence in biology" Day

Annonce/Flyer

The Institut de Biologie Structurale organizes a "Fluorescence in biology" day. A dozen speakers from IBS, EMBL, iRTSV, GIN, IAB, LiPhy will present their work based on diverse fluorescence microscopy or spectroscopy techniques as well as the associated platforms. This event is meant to be informal, is associated with the support of the Labex Gral, and aims at promoting exchanges and collaborations. Subscription is free but compulsory.

Program(me)

A detailed program is attached. Contact : Dominique Bourgeois.

The Institut de Biologie Structurale (IBS) is located in the area of Grenoble called ’EPN Science Campus’ and information to access the site is available at www.ibs.fr. Visitors to the EPN science campus must be registered for a visit prior to arrival. In order to preprare this registration, please send your surname, name, place and date of birth, nationality as well as the name of your employer to Odile Kaikati. You will need to produce proof of identification (e.g. passport, ID card) to be able to enter.

Hercules School 2014

This 4-week school is a yearly event, established in 1991. It provides training for students, postdoctoral and senior scientists from European and non-European universities and laboratories, in the field of Neutron and Synchrotron Radiation for condensed matter studies (Biology, Chemistry, Physics, Materials Science, Geosciences, Industrial applications).

It includes lectures, practicals, tutorials, and visits of Large Facilities.

Two IBS researchers (F.Gabel and J. Peters) are part of the organizing committee and many IBS scientists will give lectures and tutorials (David Cobessi, Leandro Estrozi, Adrien Favier, Eric Girard, Daphna Fenel, Guy Schoehn et Monika Spano).

For details, please have a look on the website of the course.

Native Mass Spectrometry and its Application in Structural Biology

Native Mass Spectrometry is a tool that allows the structural investigation of protein complexes and can be used to investigate biological systems. The mass of proteins can be determined, but also the stoichiometry of an assembly, its stability, dynamic behaviour, conformation, and topological arrangement within a complex. MS Vision has been involved in pioneering this new application field, together with a number of leading European Science groups.
The program highlights some of the latest developments (détails) and the lectures will be followed by a lab tour at the new facility of IBS.

Attending this symposium is free. Please register here..

2014 International year of crystallography

The UN General Assembly proclaimed 2014 the International Year of Crystallography ! With 23 Nobel Prize awarded in the field , it is the most powerful instrument for studying the structure of matter. This science is ubiquitous in everyday life : pharmaceutical production, nanotechnology, biotechnology, development of all new materials… Cristallography underpins most technological developments in our modern society, ranging from toothpaste to aircraft components .

Many events are organized throughout France by different partners and especially in Grenoble by the committee "100 years of crystallography " in which IBS is involved. Co- organizer of the symposium " Bragg - Crystallography for life" in late 2013, the Institute organizes Open Days during the Science Fair in October 2014.

To know more :

 AICr2014 : International Year of crystallography website
 International Year of Crystallography brochure in PDF : Crystallography matters !
 Unesco : Why a year of crystallography ?

Bragg symposium - Crystallography for life

To celebrate founding of X-ray crystallography by Lawrence Bragg, a Bragg Symposium will be held at EPN Campus on Thursday, 28th of November 2013 :
 Program
 Registration required
 Venue

’Structural Glycosciences’ Workshop

Details

The IBS, the CERMAV, the ESRF, and the ILL are organizing a workshop to give young scientists an integrative/multidisciplinary overview of the different approaches that can be used for characterizing the threedimensional structures of glycans, glycoconjugates or protein/glycoconjugates complexes. Current methods for analyzing the kinetics and thermodynamics of the interaction between a glycoconjugateand a protein receptor will also been covered.

ESONN 2013

ESONN is a three-week course aimed at providing training for graduate students, postdoctoral and junior scientists from universities and laboratories, all around the world, in the field of Nanosciences and Nanotechnologies.
The academic and practical courses will cover aspects such as the elaboration, characterization and functionalities of nano-objects.
The program emphasizes the role of laboratory courses (half of the program is devoted to practical work)and IBS scientists are involved in practical courses for the biological session.

 Study of biomolecular interactions by surface plasmon resonance biosensor analysis (BIAcore technology) by Nicole Thielens, Institut de Biologie Structurale, CNRS, CEA and UJF. (PDF)

More information on ESONN web site.

ICBIC 2013 : International Conference on Bioinorganic Chemistry

For the first time, ICBIC will be held in France, in Grenoble in 2013.This conference regroups about 900 international scientists from all over the world. Christine Cavazza (IBS) is a member of the organizing committee of this conference which covers all the aspects of bioinorganic chemistry including : Metalloproteins and enzymes ; Metals in medicine and health ; Metal homeostasis and trafficking ; Metals and nucleic acids, Bioinspired coordination and organometallic chemistry ; Bioinspired catalysis.
We will have four parallel sessions each day, with 64 keynote lectures and about 80 submitted oral communications. Six plenary lectures will be given by internationally recognized scientists : Franck Neese, Thomas O’Halloran, Markus Ribbe, Jean-Michel Savéant, Kazuyuki Tatsumi and Eva Toth. Two poster sessions are also scheduled.
We are confident that ICBIC16 will be a stimulating and exciting meeting in the tradition of past ICBIC conferences.
More information is available at : http://icbic16.com.
Deadline for abstract submission : April 30, 2013.

Practical course on Biophysical characterisation of soluble and membrane proteins

Program(me)

The aim of this course, organized by C.Ebel, is to present to AUC users, including beginners, the principles and potential of AUC, PAOL, TLC & TSA, and in vitro synthesis.

EMBO Practical Course "Small Angle Neutron & X-ray Scattering from Proteins in Solution"

This course will cover the use of small angle scattering (SAS) of both neutrons and X-rays for the determination of the structures of biological macromolecules. The aim is to enable the participants to maximise the information gained from the SAS technique in their future experiments.
This course is organized by the PSB partners (ESRF, ILL, EMBL, UVHCI and IBS). Frank Gabel (IBS) is a member of the organizing committee.
Frank Gabel, Joe Zaccai and Guy Schoehn (IBS) will give lectures during the workshop.
Information and registration on the dedicated website.

Workshop “Advanced methods in integrated structural biology of membrane proteins”

A technical workshop (3 days) will follow between May 27 and June 15, 2013.
This workshop aims to expose the major technological progress in structural, structure-function and dynamic studies of membrane proteins to attendees interested in those fields. In fine, all attendees will :
1) have a global outlook of difficulties encountered in membrane protein structural studies,
2) get answers to solve them with latest knowledge, and
3) interact directly with national and international experts.
Information and registration. Registration deadline : January 25th, 2013
This workshop is organized by Eva Pebay-Peyroula and Christophe Moreau (IBS) and Daniel Picot (IBPC)

HERCULES School 2013

The registration is opened for the next HERCULES session (Higher european research course for users of large experimental systems). This one month course organized by the Université Joseph Fourier (UJF) and Grenoble INPG is designed to provide training for students, postdoctoral and senior scientists from European and non-European universities and laboratories, in the field of Neutron and Synchrotron Radiation for condensed matter studies.
An IBS researcher (F.Gabel) is part of the organizing committee and many IBS scientists will give lectures and tutorials.
For details, please have a look on the website of the course.

SFBBM-SFB 2012 congress : “From molecular mechanisms to integrated life processes”

This conference is organized by the SFBBM and the SFB, in partnership with the thematic groups Archaea, Biostruc, GGMM (modelling), the SFPb, and the Labex Grenoble Alliance for Integrated Structural and Cellular Biology (IBS/iRTSV/UVHCI).

Understanding the processes supporting life is now served by recent advances allowing to bridge the gap between the study of individual molecules and the understanding of their functioning in a cellular context. The SFBBM-SFB 2012 congress will bring together about 300 scientists interested in innovative methodologies to understand key cellular processes.

Thirteen sessions will be organized with three keynote speakers, Jules Hoffmann, Ernst Bamberg and Carlos Bustamante. About 50 oral presentations will be selected among the participants from submitted abstracts. Five poster sessions are planed, and about ten poster prices attributed. To know more : http://sfbbm-sfb2012.org

Deadline : grant application : 15th June ; application for an oral presentation : 15th September ; poster abstract : 30th October.

Meeting ’Structural Dynamics and Dynamical Structures’

This meeting will focus on the future challenges for neutron techniques to answer the questions raised by molecular and cell biology. It will be a tribute to the work of Joe Zaccai who has pioneered the use of neutron diffraction and spectroscopy for the study of the structure and dynamics of biological systems, covering the range from small biomolecules to entire cells.

Current developments in the exploration of the physico-chemical limits for life, especially in relation to the role of water and salt, molecular adaptation, protein dynamics, structure and stabilisation in organisms that live under extreme conditions of salinity, temperature, pressure, and exobiology will be covered.

Deadline for abstract submission is June 30th 2012.
Further information can be found on the symposium web-site or by contacting the organizers at sdds2012@ill.eu.

Download here call for EPJE Focus Point on "Neutron Biological Physics". All contributions are welcome even from scientists unable to attend the meeting. All submitted manuscripts will be peer-reviewed according to the usual publication process of EPJE.

Organizing committee :
B. Demé, G. Fragneto, F. Gabel, P. Timmins, H. Schober

COSMX2012 - Training course in complementary optical spectroscopies

The IBS, the ESRF, the EMBL, the Swiss Light Source and Diamond are organizing a training course in optical spectroscopic methods complementary to macromolecular crystallography that will take place at the ESRF next September (19th to 21th). This course is open to students, postdocs, as well as technical and scientific staff. The first day of the course will be devoted to the presentation of the instruments, techniques (essentially UV-visible light absorption, fluorescence, Raman) and methods that are available at the three synchrotrons. The second day will feature hands-on practicals on the various instruments of the ESRF (which includes the IBS/ESRF platform Cryobench) and data analysis practicals.

The deadline for application is Friday July 20th. You can find the preliminary program and details on how to apply here.

Please note that the course is cofinanced by Biostruct-X and the ESRF, hence there is no registration fee for academics.

If you have any question, please contact Daniele de Sanctis (ESRF) or Antoine Royant (IBS).

ESONN 2012

ESONN (European school on Nanosciences and nanotechnologies) is a three-week course aimed at providing training for graduate students, postdoctoral and junior scientists from universities and laboratories, all around the world, in the field of Nanosciences and Nanotechnologies.
The program emphasizes the role of laboratory courses (half of the program is devoted to practical work) and IBS scientists are involved in practical courses for the biological session : :
 Recombinant protein production using automated liquid handling systems by Marjolaine Noirclerc-Savoye (PDF)
 Study of biomolecular interactions by surface plasmon resonance biosensor analysis (BIAcore technology) by Nicole Thielens (PDF)
 Cryo-Electron microscopy and image analysis of the adenovirus particle by
Guy Schoehn (PDF)
 Droplets for the Study of Membrane Protein by Anne Martel (PDF)
More information on ESONN web site.

IDPbyNMR Intensive Training Course : NMR methods for the study of structural order and disorder in proteins

The course will focus on theoretical and practical aspects of modern multidimensional NMR spectroscopy and molecular modeling, to characterize Intrinsically Disordered Proteins (IDPs).
Bernhard Brustcher (IBS/NMR) is member of the Organizing Committee.
Information and registration

SFP-SFB Minicolloquium : From lipid bilayers to membrane Proteins

JM. Jault (IBS/M&P) is part the organizers of this mini-colloquium which will be held during the 13th Journées de la Matière Condensée journées de la Matière Condensée.
The aim of this minicolloquium is to focus on the wide range of topics in the area of biological membranes, from the microscopic scale with vesicles or proteo-liposomes, to the nanometer scale with membrane proteins (détails).

XXVth International Conference on Magnetic Resonance in Biological Systems

This conference, held biennially, is widely considered one of the leading meetings in the rapidly growing field of magnetic resonance in biology, covering important new developments and biological applications using high-resolution liquid and solid-state NMR, EPR, in vivo NMR, metabolomics and MRI.
This event is organised by Muriel Delepierre and Anne Lecroisey (Institut Pasteur) and Martin Blackledge (IBS/FDP) is member of the scientific commitee.
Information and registration

Biomolecular NMR Mini-symposium

On the Side of the XXVth International Conference on Magnetic Resonance in Biological Systems to be held in Lyon on August 19-24 2012, we are pleased to welcome at the IBS three experts in the field of magnetic resonance in biology :

 Pr. J. CHOU (Harvard medical School, Boston), expert in structural studies of membrane proteins in solution,
 Pr. M. KAINSHO (Tokyo Metropolitan University), One of the pioneer in the field of Cell-free expression and isotopic labelling of protein
 and Pr. S. VAN DOREN (University of Missouri , Columbia) , specialist in the studies of protein-protein interaction involved in arthrosclerosis and Cancer diseases.

Contact for this mini-symposium : J. Boisbouvier / B. Brutscher.

EMBO Course on Macromolecular Complexes

This course consists of morning lectures and afternoon practicals. These generally cover different biochemical and biophysical techniques used to facilitate the structural study of macromolecular complexes (final program).
Carlo Petosa (IBS/VIC) and Guy Schoehn (IBS/MEM) co-organize with 3 other PSB researchers this EMBO course.
To know more : http://events.embo.org/12-characterization/

Workshop "Structure Determination of proteins by NMR"

The aim of this course is to enable the participants to deepen their knowledge of modern liquid-state NMR tools to study protein structure and dynamics.

Formulaire inscription / registration form

This course is organized by the IBS Biomolecular NMR Group and the Laboratoire de Chimie et de Biologie Structurales of the ICSN.

Registration
Sent registration form by email to ibs.evt.nmr-school@listes.ibs.fr, with CV

Deadline for applications :
April 20 (only 18 places)

15th GEM (French Membrane Group, Member of French Biophysical Society) meeting

The aim of this conference is to gather junior and senior scientists to discuss about the latest developments on Membranes from physical, chemical and biological point of views.

Six different sessions are scheduled (with confirmed guest speakers) :

 "Biomimetic membranes" , Pr. Linda JOHNSTON (Ottawa, Canada)

 "Drug delivery", Pr. Patrick COUVREUR (Chatenay-Malabry, France)

 "Membrane-associated peptides and proteins", Pr. Chris TATE (Cambridge, UK)

 "Membrane trafficking", Pr. Ludger JOHANNES (Paris, France)

 " In silico membrane models", Pr. Mark SANSOM (Oxford, UK)

 "Molecules-membranes interactions", Pr. Michèle AUGER (Québec, Canada)

Registration and abstract submission are now opened. More information are available on the conference website : http://gem15.fr. You can also contact Franck Fieschi (IBS/ Membrane and Pathogens Group), member of the GEM scientific committee.
Deadline for abstract submission : february 20, 2012.

Seventh International Workshop on X-ray Damage to Biological Crystalline Samples

This workshop, organized by Martin Weik (IBS/DYNAMOP) and Elspeth Garman (Oxford University) will be of interest to all those using ionising radiation to examine biological structures at the molecular level. It will consist of around 30 talks of 20-25 minutes each. To know more...

Women in Structural Biology Symposium

This symposium was organised by Malene Ringkjøbing Jensen (IBS/FDP) and financed by CEA, Bruker and Agilent.

Speakers

Membrane Protein Crystallization Symposium

The first day (14th of November) is devoted to presentations (see > program below), the second day (15th) to practicals on the lipidic phase robot. The first day will be open to all participants, and we will select the participants for the practicals.

Programme :

• 10h30-11h - Welcome and introduction (E.Pebay-Peyroula, IBS)
• 11h-11h45 - LCP crystallization : a 15 years perspective (E. Landau, OCI Univ. Zurich)
• 11h45-12h30 - Structure and mechanism of respiratory complex I (L. Sazanov, MRC Cambridge)
• 12h30-14h - Break (possible to have lunch at the ILL/ESRF canteen)
• 14h-14h45 - Thermostabilisation and structure determination of an agonist-bound conformation of the human adenosine A2A receptor (G. Lebon, Montpellier, previously MRC Cambridge)
• 14h45-15h30 - Lipidic cubic phase technologies for structural studies of membrane proteins (V. Cherezov, Scripps)
• 15h30-16h00 - Membrane proteins at IBS : the new crystallization platform (V. Gordeliy, IBS) Discussion with PhD students and post-docs

Organisers : Eva Pebay-Peyroula and Valentin Gordeliy (IBS)

Registration : Registration is mandatory (no fees, participants take in charge their housing and lunch)

Access Request  : please contact Linda Ponnet with the following data : Date, City, Country of birth, Working Institution.

Membrane Proteins GDR plenary Workshop

This meeting brings together French scientists involved in the study of membrane proteins. Program 2011 (forthcoming).

Biennial congress of the French Group of Bioenergetics

The GFB (French Group of Bioenergetics) organizes a biennial conference dedicated to research in bioenergetics and which gathers a hundred participants. It is also an opportunity for a number of young researchers to present their work.

The scientific committee includes researchers from the CEA Grenoble (Cécile Breyton IBS) and Saclay, Bordeaux, the IBSM (Marseille), the University of Nice and INSERM (Paris). For more details, visit the website of the GFB.

EMBO Meeting 2011

Registration for this conference, organized by Pascale Cossart (Pasteur Institute), Barry Dickson (IMP Austria) and Jane Langdale (Oxford, UK) are now open.
Andrea Dessen (Bacterial Pathogenis Group) is organizing one of the twelve workshops entitled "Structural Basis of prokaryotic cellular targeting and infection ’.
Information and registration.

ESONN 2011

This 3 weeks course aims at providing training for graduate students, postdoctoral and junior scientists from European universities and laboratories in the field of NANOSCIENCES and NANOTECHNOLOGIES in Physics, Biology and Chemistry. It is co-organized by University Joseph Fourier, Grenoble INP, CNRS and CEA.
Scientists of the IBS are involved in practical courses for the biological session :

• Study of biomolecular interactions by surface plasmon resonance biosensor analysis (BIAcore technology) by Nicole Thielens (PDF)
• Cryo-Electron microscopy and image analysis of the adenovirus particle by Guy Schoehn (PDF)
• Recombinant protein production using automated liquid handling systems by Marjolaine Noirclerc-Savoye (PDF)
  More information on ESONN web site.

7th Oxidase Club

The 7th oxidase club will be held in Grenoble on 26 and 27 May 2011. The organizers of this meeting (F. Fieschi (IBS), K. H. Krause et F. Morel), as well as researchers of their teams, will be pleased to welcome you on the CRSSA site (La Tronche).
This conference was born in Grenoble in 2000 with the aim to gather French research teams around the NADPH oxidase, promote contacts in a friendly atmosphere and develop constructive partnerships. This club is now organized every two years, alternatively with the prestigious Gordon Conference on NOX.
More information on the conference website (in french only).

EMBO Practical Course "Small Angle Neutron & X-ray Scattering from Proteins in Solution"

This course will cover the use of small angle scattering (SAS) of both neutrons and X-rays for the determination of the structures of biological macromolecules. The aim is to enable the participants to maximise the information gained from the SAS technique in their future experiments.
This course is organized by the PSB partners (ESRF, ILL, EMBL and IBS). Frank Gabel (IBS) is member of the organizing committee.
Frank Gabel and Jorge Navaza (IBS) will give lectures during the workshop.
Information and registration on the website of the course.

Practical Course on NMR and Biological Interactions

The aim of this course is to enable the participants to deepen their knowledge of modern technics to study interactions involving proteins by liquid NMR.

This course is organized by the IBS NMR Group and the Laboratoire de Chimie et de Biologie Structurales of the ICSN.

Information and registration (before April 8) on the website of the course.

HERCULES XXI

HERCULES (Higher european research course for users of large experimental systems) is organized by the Université Joseph Fourier (UJF) and the Institut National Polytechnique de Grenoble (INPG), together with the support of partner synchrotron radiation and neutron large facilities.
This European course is designed to provide training for students, postdoctoral and senior scientists (75 in 2011), in the field of Neutron and Synchrotron Radiation for condensed matter studies. Two IBS researchers(J. Peters and R. Kahn) are part of the organizing committee and a dozen IBS scientists will give lectures and tutorials. Program.
For details, please have a look on the website of the course.

ESONN (European school on Nanosciences and nanotechnologies)

This 3 weeks course is aimed at providing training for graduate students, postdoctoral and junior scientists from European universities and laboratories in the field of NANOSCIENCES and NANOTECHNOLOGIES in Physics, Biology and Chemistry. The academic and practical courses cover the elaboration, functioning and characterization of nano-objects. The program emphasizes the role of laboratory courses (half of the program is devoted to practical work).

Three practical courses were organized by IBS labs for the Biological sessions :
 Electron microscopy and image analysis on adenovirus
by Emmanuelle Neumann and Daphna Fenel (IBS/LMES)
 Recombinant protein production using automated liquid handling systems by Marjolaine Noirclerc-Savoye and Benoît Gallet (IBS/LIM)
 Study of biomolecular interactions by surface plasmon resonance biosensor analysis (BIAcore technology) by Nicole Thielens (IBS/LEM)

More information on ESONN web site.

Workshop "Structural Glycoscience : methods and instrumentation

The "Membrane and Immunity" team of Franck Fieschi, from the laboratoire
des protéines membranaires, co-organize this workshop with Serge Perez from the ESRF.

Glycoscience is a rapidly expanding and exciting field that is relevant
to many areas of chemistry, biology and medicine. Glycans structure is of a direct importance since they are key structural elements in cell and in signalling events on their surface.
The workshop will train young scientists, from a chemistry or biology
background, in the most up-to-date approaches for determining the structural and dynamic properties of carbohydrates, glycan binding receptors, analysis of their complexes and notably in the context of immunity and host-pathogen interaction.

This workshop is financed by the ITN marie curie Network CARMUSYS and the European Science Fundation. There is no registration fee and some
fellowship are availabel for student to cover accomodation and part of
travel expenses.

Organizing comitee : Franck Fieschi, Anne Imberty, Serge Perez.

EMBO Course : Structural Characterization of Macromolecular Complexes

Program EMBO 2010

This six-day course, co-organised by Carlo Petosa, aims to teach the strategic use of biochemical and biophysical techniques to expedite structural studies of macromolecular complexes. The primary focus is on how to produce, purify and characterize multi-subunit protein and protein/nucleic acid complexes for structural analysis.
For details, please have a look on the Website of the course

All PSB members and local area scientists are welcome to attend the morning lectures, which will be held in the ILL Chadwick Amphitheatre (Sat. June 5 in the EMBL seminar room). Visitors requiring a site entry are requested to contact Mary Jane Villot (villot@embl.fr)

PSB Science Day : Dynamics in Biology

13:30 : Welcome

First Session

 13:35 - 14:20 : Martin Field (IBS)
Molecular simulations of enzyme catalysis

 14:20 - 15:05 : Michael Wulff (ESRF)
The structure function relationship in protein reactions initiated by light.

 15:05 - 15:25 : Colin Jackson (IBS)
How structural dynamics in an enzyme enhance catalytic efficiency and evolvability.

 15:25 - 15:45 : Cedric Leyrat (UVHCI)
Structural dynamics of the Rhabdoviridae replication complex

15:45 - 16:05 : Coffee break

Second session

 16:05 – 16:50 : Jo Zaccai (ILL)
High-throughput neutron scattering approach to protein dynamics

 16:50 – 17:35 : Martin Blackledge (IBS)
NMR studies of the role of molecular flexibility in protein function

 17:35 : End of the Session and Conclusions

Microbiology Interaction Day

Programme

This scientific day will be held in the IBS Seminar room from 9:45 am to 5 pm. It will be opened to anyone interested in this subject.

Protein Crystallography course for PhD students and Postdocs of the Structural Biology of Membrane Proteins program

The course is designed for postdocs and graduate students who are interested in protein X-ray crystallographic projects but who may not have had any formal training in the theory and practice of macromolecular crystallography.
The topics to be covered and other details are listed on the flyer of the course.

EMBO Course : Combination of electron microscopy and x-ray crystallography

This six-day course, co-organised by Jorge Navaza, will be given at the ESRF and will cover the major aspects of :

• Use of- Iterative fitting of atomic models into EM 3D maps for pseudo-atomic model building.
• EM 3D maps as models for X-ray molecular replacement.

For details, please have a look on the Website of the course
Deadline for applications is : 15th September 2009

What is a macromolecular complex ? (Workshop)

This workshop, organised by Carlo Petosa (IBS), Stephen Cusack (EMBL),
Andrea Musacchio (IEO, Milan) and Anastassis Perrakis (NKI, Amsterdam), brings together macromolecular, cellular, systems and structural biologists to share knowledge and experience. It aims to discuss problems commonly encountered by structural biologists when working with macromolecules inferred to form a complex from functional data (e.g., yeast two hybrid assays, co-IP, TAP-tagging, network analysis). More information on the website.

Deadline for registration : September 7

6th International Conference on Proteoglycans

The next international meeting on proteoglycans will be held in France, organized by the Institute for Structural Biology (IBS).

The conference, which has been held every two years since 1997, aims at promoting the development of this emerging field at an international level. During the previous meeting (Rio de Janeiro ; Brazil 2007), France was selected to organize the 2009 edition.

Program and registration.

ESONN (European school on Nanosciences and nanotechnologies)

This 3 weeks course is aimed at providing training for graduate students, postdoctoral and junior scientists from European universities and laboratories in the field of NANOSCIENCES and NANOTECHNOLOGIES in Physics, Biology and Chemistry.
The academic and practical courses cover the elaboration, functioning and characterization of nano-objects. The program emphasizes the role of laboratory courses (half of the program is devoted to practical work).
More information on ESONN web site.

TSRC Workshop on Protein Dynamics

This workshop, which is held every two years, is dedicated to presentation and discussion about experimental research (NMR, crystallography, various methods of spectroscopy, neutrons, ...) and protein dynamics simulation. The workshop is limited to thirty participants, who will all present their work. Despite its small size, attendants to the workshop come from almost all over the world : U.S., Europe and Asia.

In 2009, the workshop is co-organized by Martin Weik (Institut de Biologie Structurale, Grenoble), Ralph Jimenez (University of Colorado), Yasuhisa Mizutani (Osaka University), and Joshua Wand (University of Pennsylvania).

For more information visit the TSRC Workshop web site.

Fourth IBS Scientific Day

The annual Scientific Day of the IBS will be held on 29 June 2009 on the Saint Martin d’Hères Campus.

This meeting will bring together all the IBS labs to improve internal scientific communication and offer the opportunity to initiate collaborative projects. Four plenary lectures are scheduled (for the main research themes), as well as presentations of new techniques available at the IBS and poster sessions presented by all Ph.D. students.

Super resolution optical microscopy : principles and applications to life sciences

This workshop, jointly organised by the IBS, the "Laboratoire de Spectrométrie Physique" (LSP), the iRTSV and the Nanosciences Fondation, aims at discussing about fluorescence super-resolution microscopy, a tool which opens fascinating perspectives for in cellulo structural biology.

Workshop program and registration.
For the location click here

International Workshop on High Field Solution and Solid State Biomolecular NMR

The aim of the workshop is to bring together solution and solid state NMR biomolecular communities in order to discuss recent advances in areas of molecular dynamics and folding, studies of challenging biomolecular systems, advances in structure determination, new concepts and experimental techniques, use of paramagnetic labeling.
The program features presentations from leading scientists as well as recent outstanding contributions from younger colleagues. The workshop is opened to the entire biomolecular NMR community and should yield exciting discussions as well as strong informal after session exchanges. The number of participants will be limited to 70.

Organising Committee

 J. Boisbouvier (Grenoble)
 C. Bougault (Grenoble)
 B. Brutscher (Grenoble)
 G. De Paëpe (Grenoble)
 S. Hediger (Grenoble)
 D. Marion (Grenoble)
 G. Pintacuda (Lyon)

Organising institutions

 Nuclear Magnetic Resonance Lab (LRMN) - IBS Grenoble
 Institut Nanosciences et Cryogénie
 Centre Européen de RMN à Très Hauts Champs

Address for correspondence

Email to nmr.houches-2009@ibs.fr

Venue and accommodation

The workshop starts on Monday 1st with dinner, and ends on Friday 5th after lunch. The workshop will take place at the Les Houches Physics Center in Savoie (close to Chamonix) facing the Mont-Blanc. On the edge of woods and meadows, set apart from the village itself, it offers many opportunities for activities such as hiking and mountain-climbing. During the workshop, the afternoons will remain free for outdoor activities and scientific discussion. More practical information can be found here.
Les Houches can be reached by car, train, or airplane to Geneva (map).

Invited speakers

B. Reif (Germany), M. Tollinger (Austria), D. Hsu (UK), P. Schanda (Switzerland), R. Sprangers (Germany), M. Baldus (The Netherlands), M. Jensen (France), G. Jeschke (Switzerland), M. Lelli (Italy), T. Herrmann (France), P. Selenko (Germany), E. Lescop (France), M. Gal (Israel), G. De Paëpe (France), C. Glaubitz (Germany), C. Van-Heijenoort (France), C. Jaroniec (USA), I. Felli (Italy), G. Pintacuda (France), C. Griesinger (Germany), F. Hansen (Canada), V. Doetsch (Germany).

Registration

Sent registration form (rtf or pdf) by email with the poster abstract to : nmr.houches-2009@ibs.fr.

Analytical Ultracentrifugation, Practical course 2009

Analytical Ultracentrifugation (AUC) is a unique technique, based on rigorous thermodynamic basis, for the characterization of solution homogeneity, macromolecule interactions, masses and shape in solution.

The aim of this course, organized by C.Ebel, is to present to AUC users, including beginners, the principles and potential of the technique, and to provide step by step tutorials for analyzing data, using some examples of sedimentation velocity and equilibrium. The free Sedfit and Ultrascan softwares developed respectively by P. Schuck and B. Demeler will be used.

Information and registration

RMN and Biological Interactions

This five days course is jointly organized by the Laboratory of Nuclear Magnetic Resonance (IBS, Grenoble) and the High Field Nuclear Magnetic Resonance Laboratory (ICSN, Gif-sur-Yvette).

It will allow students to learn and practice recently developed methods in NMR with a strong emphasis on interactions between proteins and their biological partners (proteins, nucleic acids, ligands).

For further information, visit the course web site.

Membrane Proteins GDR plenary Workshop

This meeting, organized by Eva Pebay-Peyroula, brings together French scientists involved in the study of membrane proteins. Program of this fourth edition.

PSB Minisymposium : Frontiers of Membrane Protein Structure

Two conferences hosted by Eva Pebay-Peyroula (IBS) and Imre Berger (EMBL)) (program) :

 14H00 Structural Studies of the potassium channel by Joao MORAIS CABRAL (IBMC Instituto de Biologia Molecular e Celular, Porto, Portugal)
 15H00 Structural and mechanistic studies of ABC transporter proteins by Kaspar LOCHER (Institute for Molecular Biology and Biophysics IMB, ETH Zurich, Switzerland)

Please contact I.Berger ( iberger@embl.fr) for more details and MJ.Villot (villot@embl.fr) for site entrance registration to Polygone.

French Structural Biology Day

The purpose of the meeting is to take stock of the current state of structural biology in France in terms of ongoing projects, positioning within the wider European context, and long-term vision (program).

Organizing committee :
 Eva Pebay-Peyroula
 Yves Bourne
 Dino Moras
 Stephen Cusak
 Félix Rey

International Conference on High-Pressure Molecular Biophysics

HPMB2008 took place on December 10th-12th 2008 at the new third generation synchrotron radiation facility SOLEIL, located at Saint Aubin, near Saclay and Orsay, in the vicinity of Paris.
By the end of 2008, at least 11 beamlines of SOLEIL operated routinely, providing an exciting context for the conference.
The meeting was jointly organized by SOLEIL and two large biophysical laboratories : the Centre de Biophysique Moléculaire (CBM, Orléans) and the Institut de Biologie Structurale (IBS, Grenoble).
Program and registration

Biological Physics at large Facilities : From Molecule to Cell

This workshop, jointly organized by ESRF, ILL and IBS, brought together the Biology and Physics communities for a discussion on the state-of-the-art and future perspectives of physics instrumentation and methods for the study of biological structures and dynamics at neutron sources and synchrotron radiation facilities.. Details

IN13 User Meeting

Presentation of experimental results obtained on IN13. Suggestions for a better use of instrument performance and discussion about requirements and further improvements. Incentives to closer collaborations between groups. Programm and registration

25th French Mass Spectrometry Meeting

This meeting, organized under the auspices of theFrench Society for Mass Spectrometry, gathers annually French-speaking researchers interested in mass spectrometry. Several members of the LSMP were involved in the 2008 organization.
For further information, visit http://jfsm2008-grenoble.ibs.fr/.

Membrane Proteins GDR plenary Workshop

This meeting, organized by Eva Pebay-Peyroula, brought together French scientists involved in the study of membrane proteins. Program of this third edition. .

EMBO Practical course : Combination of electron microscopy and X-ray crystallography

This course organized by two IBS scientists and a LVMS scientist allowed students to learn and practice recently developed methods allowing the combination of Electron Microscopy and X-ray crystallography in particular :

 Fitting of X-Ray models into EM reconstructions, including flexible fitting with normal modes analysis.
 Use of an EM reconstruction as an initial phasing model to determine a crystal structure at higher resolution.

Information : http://mem.ibs.fr/UROX, Registration : http://cwp.embo.org/pc08-10/.

Associated Workshop to the ESRF Users’ Meeting 2008 : Structural and Molecular Biology of Host-Pathogen Interactions

This workshop jointly organized by ESRF/IBS/ILL/EMBL will focus on recent advances at the intersection of Structural biology and Host-pathogen interactions with a strong emphasis on what structural biology has brought to the field. This three half days should allow scientists, post-docs and students from various fields to gather and share their experiences

For more information : click here

PSB Science Day : NMR a tool for Structural Biology

A PSB Science/Student’s Day will take place in the ESRF auditorium, Monday 10th December. The morning session will focus on the availability and possibilities - within the PSB - of NMR a tool for structural biology while the afternoon session will be devoted to presentations from students associated within the PSB and will also include a series of short ’poster clip’ presentations as well as a poster session. Program.

For more information, please contact :B.Brutscher

PSB Science Day : NMR a tool for Structural Biology

A PSB Science/Student’s Day will take place in the ESRF auditorium, Monday 10th December. The morning session will focus on the availability and possibilities - within the PSB - of NMR a tool for structural biology while the afternoon session will be devoted to presentations from students associated within the PSB and will also include a series of short ’poster clip’ presentations as well as a poster session. Program.
For more information, please contact : B.Brutscher

GDR plenary Workshop

The 2007 plenary meeting of the GDR will be held in Grenoble from december 3 to 4th. The meeting will focus on biological macromolecules dynamics and combination of multi-resolution results. Organizing committee : Guy Schoehn and Emmanuelle Neumann (IBS/LMES).

10th Rhone-Alpes NMR Day

The 10th Rhone-Alpes NMR Day will be held on October 5th, in the Hotel de la Poste of Charavines (Isère). (Poster).

This meeting will bring together NMR spectroscopists of the Rhone-Alpes area. It will offer the opportunity for research teams to initiate collaborative projets and for young scientists to present their most recent results.

Two plenary lectures are scheduled :

 Paul Driscoll (University College London - UK) : NMR, biochemical and biophysical probing of domain interactions from the CD95 death-inducing signalling complex
 Anja Böckmann (IBCP – Lyon) : Protein high-resolution 3D structure determination by solid-state NMR

and ten short oral presentations will be selected among the submitted posters.

Information : D.Marion, Registration : registration form

10th Conference of the French Society of Microscopy

This conference jointly organized by all local research organisms (CNRS, CEA, INPG, UJF) was be held at the MMNT - Minatec in Grenoble.

Recent developments in microscopy (as well for physical and/or biological applications) were reviewed through 20 symposiums held during this conference.

Information and registration : http://sfmu2007.free.fr/

International Workshop on Spectroscopy around biological crystallography

The International Workshop on Spectroscopy around biological crystallography jointly organized by ESRF and IBS took place in Grenoble (IBS and ESRF), February 6-8, 2007.

The purpose of this workshop was to review the recent developments at synchrotron sources of spectroscopic techniques complementary to X-ray diffraction, as well as the new science that is starting to emerge from using such integrated approaches.

Details

International Workshop on Advanced Laue Diffraction in Frontier Science

The International Workshop on Advanced Laue Diffraction in Frontier Science jointly organized by ESRF/IBS/ILL/LLB took place in Grenoble, January 23-27, 2007. This workshop brought together the neutron and X-ray communities working with Laue diffraction. Attendees also had the opportunity to visit the state-of-the-art Laue facilities at both the ESRF and the ILL.

For more information : Web Site :http://www.ill.fr/Events/laue2007/

Third Japanese-french Seminar on Structural Dynamics of Proteins

This seminar jointly organized by IBS, ILL and JSPS was held from January 15-19, 2007 at the ESRF auditorium in Grenoble.

This seminar, which is held every six years, focuses on the study of structural dynamics and its implication in protein function. It covers several biophysical techniques including NMR, neutron scattering, kinetic and conventional X-ray crystallography, spectroscopy and computational methods.

For further information see the (detailed program).

Gordon Research Conference on Computational Aspects of Biomolecular NMR

Please find an information sheet and a preliminary program for this conference on Computational Aspects of Biomolecular NMR to be held in Aussois on September 24 to 29, 2006.

Organizing Comittee :
 Chair : Martin Blackledge, IBS Grenoble, France
 Co-Chair : Rafael Brüschweiler, NHFML, Florida University, USA

To register, go to Gordon web site (bottom of page)

International School on High Field NMR Spectroscopy for Solids and Liquids

High-level pedagogical courses on a wide range of liquid- and solid-state NMR concepts and techniques.

Les Houches, France, 14-19 May 2006

The aim of the school is to offer high-level pedagogical courses on a wide range of liquid- and solid-state NMR concepts and techniques : theory, data acquisition, processing and analysis, measurement of dipolar and quadrupolar couplings, spin relaxation, and hyper-polarization. A few presentations of leading scientists on current research topics will complement the more pedagogical lectures. The school is addressed to young scientists, post-docs, and confirmed PhD students with a special interest in the complementarity of modern liquid- and solid-state NMR. The number of participants will be limited to 50.

Analytical Ultracentrifugation Practical course

Please find an information sheet for this workshop on Sedfit et Sedphat to be held in Grenoble on April 14 to 16, 2006. For more information, contact C.Ebel.

Protein-glycan interaction : biological roles and methodological approaches

Please find an information sheet for this workshop on protein-glycan interaction to be held in Toulon on March 16 to 17, 2006.

France-Sino Bilateral Symposium of Life Sciences for Women Scientists

Please find the program for the France-Sino Bilateral Symposium of Life Sciences for Women Scientists to be held on 27 October 2005 at the Jean Kuntzmann Amphitheatre on the UJF campus.

ESONN 2004 (European school on Nanosciences and nanotechnologies)

This European School, which will take place on a yearly basis, is aimed at providing training for graduate students, postdoctoral and junior/senior scientists from Universities and laboratories in the field of Nanosciences and Nanotechnologies in Physics and Biology.
The academic and practical courses will cover the fabrication, principles and characterisation of nano-objects. Some of the practical courses (biology session) will be given by IBS laboratories.

For more information, visit the ESONN’04 web site

EMBO Practical Course

The EMBO Practical Course on the "Structural Characterization of Macromolecular Complexes : Modern techniques and Strategies" jointly organized by EMBL/ESRF/IBS/IVMS will take place in Grenoble, May 3-8, 2004.

During the course there will be lectures in the morning (Chadwick Amphitheatre), practicals in the afternoon and two evening seminars (EMBL seminar room).

The program is available on the course website. This website also contains a link to further background material of the course (protocols etc.).

Workshop : Analytical Ultracentrigation

French version :

Un atelier pratique sur l’ultracentrifugation analytique aura lieu à Grenoble les 5 et 6 avril 2004. Vous pouvez cliquez ici pour accéder au bulletin d’inscription.

Pour tout renseignement complémentaire s’adresser à C.Ebel.

Workshop : structural proteomic

The preliminary program is available

French version :

Le 1er Atelier sur l’automatisation en protéomique structurale aura lieu du 11 (à 14h) au 12 mars (à 18h) 2004 à Autrans au centre de vacances MAEVA (30 km de Grenoble).

Le formulaire d’inscription est à renvoyer à Nancy Didier, avant la date limite du 15 Février 2004. Le nombre de participants est limité à 45. Un programme provisoire est disponible.

NRC/CNRS workshop on Membrane proteins

Please find an information sheet , the preliminary program and a registration form for the NRC/CNRS workshop on Membrane proteins to be held in Autrans on March 9 (19:00) to 11 (13:30), 2004.

A detailed programme will be provided following the 15, Feb deadline date for registration. We will have two guest speakers, Thierry Rabilloud and Gerard Brandolin, who will present their work and some of their kwow-how related to membrane proteins biochemistry and analysis.

Autrans 2004 (Stress and Immunity)