Module Version 1.0
Presentation
Module is a novel program developed to allow the determination of alignment tensor parameters for individual or multiple domains in macromolecules from residual dipolar couplings and to facilitate their manipulation to construct low-resolution models of macromolecular structure.
For multi-domain systems the program determines the relative orientation of individual structured domains, and provides graphical user-driven rigid-body modeling of the different modules relative to the common tensorial frame.
Translational freedom in the common frame, and equivalent rotations about the diagonalized (x,y,z) axes, are used to position the different modules in the common frame to find a model in best agreement with experimentally measured couplings alone or in combination with additional experimental or covalent information.
The program has been compiled for the following platforms :
- Mac OSX .
- PC Linux running Redhat 5.2 to 7 .
- PC Linux running Redhat 8 or 9 .
- Silicon Graphics running Irix 6.5 or higher.
- Sun Sparc running Solaris 2.6 or higher
The license is free for academic sites and non commercial use.
References
If any results obtained with the MODULE program are published, whatever the means of publication, particularly in the scientific literature, the program should be referenced in the following way:
A Novel Interactive Tool for Rigid-Body Modeling of Multi-Domain Macromolecules using Residual Dipolar Couplings. Dosset, P.; Hus, J-C; Marion, D; Blackledge, M. J.Biomol.NMR. 20:223-231, July 2001.
Documentation
Downloaded with the executable
Download
Before downloading the software, you must read the license.
If you agree the license terms, you can download the software :
– version PC :
– version MAC :