Publications since 2014
Our list of publications with peerReviewing, books and book sections since 2014 can be found below (data issued from HAL-IBS).
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Publications up to 2013
Our list of publications from 2000 to 2013 is displayed below.
Publications 2013
Appolaire A, Rosenbaum E, Dura MA, Colombo M, Marty V, Noirclerc Savoye M, Godfroy A, Schoehn G, Girard E, Gabel F and Franzetti B
Pyrococcus horikoshii TET2 peptidase assembling process and associated functional regulation.
Journal of Biological Chemistry (2013) 288(31) : 22542-22554
Bersch B, Bougault C, Roux L, Favier A, Vernet T and Durmort C
New insights into histidine triad proteins : Solution structure of a Streptococcus pneumoniae PhtD domain and zinc transfer to AdcAII.
PLoS One (2013) 8(11) : e81168
Bouguelia S, Roupioz Y, Slimani S, Mondani L, Casabona MG, Durmort C, Vernet T, Calemczuk R and Livache T
On-chip microbial culture for the specific detection of very low levels of bacteria.
Lab on Chip (2013) 13(20) : 4024-4032
Duan C, Adam V, Byrdin M, Ridard J, Kieffer-Jaquinod S, Morlot C, Arcizet D, Demachy I and Bourgeois D
Structural evidence for a two-regime photobleaching mechanism in a reversibly switchable fluorescent protein.
Journal of the American Chemical Society (2013) 135(42) : 15841-15850
Morlot C, Bayle L, Jacq M, Fleurie A, Tourcier G, Galisson F, Vernet T, Grangeasse C and Di Guilmi AM
Interaction of Penicillin-Binding Protein 2x and Ser/Thr protein kinase StkP, two key players in Streptococcus pneumoniae R6 morphogenesis.
Molecular Microbiology (2013) 90(1) : 88-102
Noirclerc-Savoye M, Lantez V, Signor L, Philippe J, Vernet T and Zapun A
Reconstitution of membrane protein complexes involved in pneumococcal septal cell wall assembly.
PLoS One (2013) 8(9) : e75522
Peters NT, Morlot C, Yang DC, Uehara T, Vernet T and Bernhardt TG
Structure-function analysis of the LytM domain of EnvC, an activator of cell wall remodelling at the Escherichia coli division site.
Molecular Microbiology (2013) 89(4) : 690-701
Zapun A, Philippe J, Abrahams KA, Signor L, Roper DI, Breukink E and Vernet T
In vitro reconstitution of peptidoglycan assembly from the Gram-positive pathogen Streptococcus pneumoniae.
ACS chemical biology (2013) 8(12) : 2688-2696
Zervosen A, Zapun A and Frer̀e JM
Inhibition of Streptococcus pneumoniae penicillin-binding protein 2x and Actinomadura R39 DD-peptidase activities by ceftaroline.
Antimicrobial Agents and Chemotherapy (2013) 57(1) : 661-663
Publications 2012
Banzhaf M, Van den Berg van Saparoea B, Terrak M, Fraipont C, Egan A, Philippe J, Zapun A, Breukink E, Nguyen-Distèche M, Den Blaauwen T and Vollmer W
Cooperativity of peptidoglycan synthases active in bacterial cell elongation.
Molecular Microbiology (2012) 85(1) : 179-194
Boncoeur E, Durmort C, Bernay B, Ebel C, Di Guilmi AM, Croize J, Vernet T and Jault JM
PatA and PatB form a functional heterodimeric ABC multidrug efflux transporter responsible for the resistance of Streptococcus pneumoniae to fluoroquinolones.
Biochemistry (2012) 51(39) : 7755-7765
Chimalapati S, Cohen JM, Camberlein E, MacDonald N, Durmort C, Vernet T, Hermans PWM, Mitchell T and Brown JS
Effects of deletion of the Streptococcus pneumoniae lipoprotein diacylglyceryl transferase gene Lgt on ABC transporter function and on growth in vivo.
PLoS One (2012) 7(7) : e41393
El Mortaji L, Contreras-Martel C, Moschioni M, Ferlenghi I, Manzano C, Vernet T, Dessen A and Di Guilmi AM
The full-length Streptococcus pneumoniae major pilin RrgB crystallizes in a fiber-like structure, which presents the D1 isopeptide bond and provides details on the mechanism of pilus polymerization.
Biochemical Journal (2012) 441(3) : 833-841
El Mortaji L, Fenel D, Vernet T and Di Guilmi AM
Association of RrgA and RrgC into the Streptococcus pneumoniae pilus by sortases C-2 and C-3.
Biochemistry (2012) 51(1) : 342-352
Fleurie A, Cluzel C, Guiral S, Freton C, Galisson F, Zanella-Cleon I, Di Guilmi AM and Grangeasse C
Mutational dissection of the S/T-kinase StkP reveals crucial roles in cell division of Streptococcus pneumoniae.
Molecular Microbiology (2012) 83(4) : 746-758
Goedhart J, Von Stetten D, Noirclerc-Savoye M, Lelimousin M, Joosen L, Hink MA, Van Weeren L, Gadella TWJ and Royant A
Structure-guided evolution of cyan fluorescent proteins towards a quantum yield of 93%.
Nature Communications (2012) 3 : n°1738
von Stetten D, Batot GO, Noirclerc-Savoye M and Royant A
Alteration of fluorescent protein spectroscopic properties upon cryoprotection.
Acta Crystallographica D Biological Crystallography (2012) 68(Pt 11) : 1578-1583
von Stetten D, Noirclerc-Savoye M, Goedhart J, Gadella TW, Jr. and Royant A
Structure of a fluorescent protein from Aequorea victoria bearing the obligate-monomer mutation A206K.
Acta Crystallographica Section F Structural Biology and Crystallization Communications (2012) 68(Pt 8) : 878-882
Zapun A, Noirclerc-Savoye M, Helassa N and Vernet T
Peptidoglycan assembly machines : the biochemical evidence.
Microbial Drug Resistance (2012) 18(3) : 256-260
Publications 2011
Amero C, Asuncion Dura M, Noirclerc-Savoye M, Perollier A, Gallet B, Plevin MJ, Vernet T, Franzetti B and Boisbouvier J
A systematic mutagenesis-driven strategy for site-resolved NMR studies of supramolecular assemblies.
Journal of Biomolecular NMR (2011) 50 (3) : 229-236
Bayle L, Chimalapati S, Schoehn G, Brown J, Vernet T and Durmort C
Zinc uptake by Streptococcus pneumoniae depends on both AdcA and AdcAII and is essential for normal bacterial morphology and virulence.
Molecular Microbiology (2011) 82 (4) : 904-916
Chimalapati S, Cohen J, Camberlein E, Durmort C, Baxendale H, de Vogel C, van Belkum A and Brown JS
Infection with conditionally virulent Streptococcus pneumoniae Dpab strains induces antibody to conserved protein antigens but does not protect against systemic infection with heterologous strains.
Infection Immunity (2011) 79 (12) : 4965-4976
Contreras Martel C, El Mortaji L, Manzano C, Terrasse R, Vernet T, Di Guilmi AM and Dessen A
Structural basis of host cell recognition by the pilus adhesin from Streptococcus pneumonia.
Structure (2011) 18 (1) : 106-115
Deniaud A, Bernaudat F, Frelet-Barrand A, Juillan-Binard C, Vernet T, Rolland N and Pebay-Peyroula E
Expression of a chloroplast ATP/ADP transporter in E. coli membranes : Behind the Mistic strategy.
Biochimica and Biophysica Acta - Biomembranes (2011) 1808 (8) : 2059-2066
Derouaux A, Turk S, Olrichs NK, Gobec S, Breukink E, Amoroso A, Offant J, Bostock J, Mariner K, Chopra I, Vernet T, Zervosen A, Joris B, Frère J-M, Nguyen-Distèche M and Terrak M
Small molecule inhibitors of peptidoglycan synthesis targeting the lipid II precursor.
Biochemical Pharmacology (2011) 81 (9) : 1098-1105
Du Y, He YX, Zhang ZY, Yang YH, Shi WW, Frolet C, Guilmi AM, Vernet T, Zhou CZ and Chen Y
Crystal structure of the mucin-binding domain of Spr1345 from Streptococcus pneumoniae.
Journal of Structural Biology (2011) 174 (1) : 252-257
Jiang YL, Yu WL, Zhang JW, Frolet C, Di Guilmi AM, Zhou CZ, Vernet T and Chen Y
Structural basis for the substrate specificity of a novel beta-N-acetyl-hexosaminidase StrH from Streptococcus pneumoniae R6.
Journal of Biological Chemistry (2011) 286 (50) : 43004-43012
Loisel E, Chimalapati S, Bougault C, Imberty A, Gallet B, Di Guilmi AM, Brown J, Vernet T and Durmort C
Biochemical characterization of the histidine triad protein PhtD as a cell surface zinc-binding protein of pneumococcus.
Biochemistry (2011) 50 (17) : 3551-3558
Mohammadi T, van Dam V, Sijbrandi R, Vernet T, Zapun A, Bouhss A, Diepeveen-de Bruin M, Nguyen-Disteche M, de Kruijff B and Breukink E
Identification of FtsW as a transporter of lipid-linked cell wall precursors across the membrane.
EMBO Journal (2011) 30 (8) : 1425-1432
Royant A and Noirclerc-Savoye M
Stabilizing role of glutamic acid 222 in the structure of Enhanced Green Fluorescent Protein.
Journal of Structural Biology (2011) 174 (2) : 385-290
Publications 2010
Almagro S, Durmort C, Chervin-Pétinot A, Heyraud S, Dubois M, Lambert O, Maillefaud C, Hewat E, Schaal JP, Huber P and Gulino-Debrac D
The motor protein myosin-X transports VE-cadherin along filopodia to allow the formation of early endothelial cell-cell contacts.
Journal of Molecular Cell Biology (2010) 30(7) : 1703-1717
Durrant JD, Amaro RE, Xie L, Urbaniak MD, Ferguson MA, Haapalainen A, Chen Z, Di Guilmi AM, Wunder F, Bourne PE and McCammon JA
A multidimensional strategy to detect polypharmacological targets in the absence of structural and sequence homology.
PLoS Computational Biology (2010) 6(1) : e1000648
El Mortaji L, Terrasse R, Dessen A, Vernet T and Di Guilmi AM
Stability and assembly of pilus subunits of streptococcus pneumoniae.
Journal of Biological Chemistry (2010) 285(16) : 12405-12415
Frolet C, Beniazza M, Roux L, Gallet B, Noirclerc-Savoye M, Vernet T and Di Guilmi AM
New adhesin functions of surface-exposed pneumococcal proteins.
BMC Microbiology (2010) 10 : 190
Gans P, Hamelin O, Sounier R, Ayala I, Dura MA, Amero CD, Noirclerc-Savoye M, Franzetti B, Plevin MJ and Boisbouvier J
Stereospecific isotopic labeling of methyl groups for NMR spectroscopic studies of high-molecular-weight proteins.
Angewandte Chemie International Edition (2010) 49(11) : 1958-1962
Izoré T, Contreras-Martel C, El Mortaji L, Manzano C, Terrasse R, Vernet T, Di Guilmi AM and Dessen A
Structural basis of host cell recognition by the pilus adhesin from Streptococcus pneumoniae.
Structure (2010) 18(1) : 106-115
Noirclerc-Savoye M, Gallet B, Bernaudat F and Vernet T
Large scale purification of linear plasmid DNA for efficient high throughput cloning.
Biotechnology Journal (2010) 5(9) : 978-985
Offant J, Terrak M, Derouaux A, Breukink E, Nguyen-Disteche M, Zapun A and Vernet T
Optimization of conditions for the glycosyltransferase activity of penicillin-binding protein 1a from Thermotoga maritima.
FEBS Journal (2010) 277(20) : 4290-4298
Publications 2009
Karst JC, Foucher AE, Campbell TL, Di Guilmi AM, Stroebel D, Mangat CS, Brown ED and Jault JM
The ATPase activity of an ’essential’ Bacillus subtilis enzyme, YdiB, is required for its cellular function and is modulated by oligomerization.
Microbiology (2009) 155(Pt 3) : 944-956
Lelimousin M, Noirclerc-Savoye M, Lazareno-Saez C, Paetzold B, Le Vot S, Chazal R, Macheboeuf P, Field MJ, Bourgeois D and Royant A
Intrinsic dynamics in ECFP and cerulean control fluorescence quantum yield.
Biochemistry (2009) 48(42) : 10038–10046
Masson S, Kern T, Le Gouellec A, Giustini C, Simorre JP, Callow P, Vernet T, Gabel F and Zapun A
The central domain of DivIB caps the C-terminal regions of the FtsL/DivIC coiled-coil rod.
Journal of Biological Chemistry (2009) 284 : 27687-27700
Rasia RM, Noirclerc-Savoye M, Bologna NG, Gallet B, Plevin MJ, Blanchard L, Palatnik JF, Brutscher B, Vernet T and Boisbouvier J
Parallel screening and optimization of protein constructs for structural studies.
Protein Science (2009) 18(2) : 434-439
Zapun A, Macheboeuf P and Vernet T (2009)
Penicillin-binding proteins and beta-lactam resistance in Antimicrobial Drug Resistance : Principles for the Clinic and Bench, vol. 1(chap.13), D. Mayers, J. Sobel, M. Ouellette and S. Lerner (eds.), Humana Press, pp 145-170
Zhang Z Y, Li W Z, Frolet C, Bao R, di Guilmi A M, Vernet T and Chen Y X
Structure of the choline-binding domain of Spr1274 in Streptococcus pneumoniae.
Acta Crystallographica Section F-Structural Biology and Crystallization Communications (2009) 65 : 757-761
Publications 2008
Attali C, Durmort C, Vernet T and Di Guilmi AM
The interaction of Streptococcus pneumoniae with plasmin mediates transmigration across endothelial and epithelial monolayers by intercellular junctions cleavage.
Infection and Immunity (2008) 76(11) : 5350-5356
Attali C, Frolet C, Durmort C, Offant J, Vernet T and Di Guilmi AM
Streptococcus pneumoniae choline-binding protein E interaction with plasminogen/plasmin stimulates migration across the extracellular matrix.
Infection and Immunity (2008) 76(2) : 466-476
Bibert S, Ayari H, Riveline D, Concord E, Hermant B, Vernet T and Gulino-Debrac D
Establishment of cell-cell junctions depends on the oligomeric states of VE-cadherin.
Journal of Biochemistry (2008) 143(6) : 821-832
Gutsche I, Vujicic-Zagar A, Siebert X, Servant P, Vannier F, Castaing B, Gallet B, Heulin T, de Groot A, Sommer S and Serre L
Complex oligomeric structure of a truncated form of DdrA : A protein required for the extreme radiotolerance of Deinococcus.
Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics (2008) 1784(7-8) : 1050-1058
Heyraud S, Jaquinod M, Durmort C, Concord E, Schaal JP, Huber P and Gulino-Debrac D
Contribution of annexin II to the architecture of mature endothelial adherens junctions.
Molecular and Cellular Biology (2008) 28(5) : 1657-1668
Job V, Carapito R, Vernet T, Dessen A and Zapun A
Common alterations in PBP1a from resistant Streptococcus pneumoniae decrease its reactivity toward beta-lactams : STRUCTURAL INSIGHTS.
Journal of Biological Chemistry (2008) 283(8) : 4886-4894
Le Gouellec A, Roux L, Fadda D, Massidda O, Vernet T and Zapun A
Roles of pneumococcal DivIB in cell division.
Journal of Bacteriology (2008) 190(13) : 4501-4511
Loisel E, Jacquamet L, Serre L, Bauvois C, Ferrer JL, Vernet T, Di Guilmi AM and Durmort C
AdcAII : A new pneumococcal Zn-binding protein homologous with ABC transporters : biochemical and structural analysis.
Journal of Molecular Biology (2008) 381(3) : 594-606
Manzano C, Contreras-Martel C, El Mortaji L, Izoré T, Fenel D, Vernet T, Schoehn G, Di Guilmi AM and Dessen A
Sortase-mediated pilus fiber biogenesis in Streptococcus pneumoniae.
Structure (2008) 16(12) : 1838-1848
Pagliero E, Dublet B, Frehel C, Dideberg O, Vernet T and Di Guilmi AM
The inactivation of a new peptidoglycan hydrolase Pmp23 leads to abnormal septum formation in Streptococcus pneumoniae.
The Open Microbiology Journal (2008) 2 : 107-114
Taveau JC, Dubois M, Le Bihan O, Trepout S, Almagro S, Hewat E, Durmort C, Heyraud S, Gulino-Debrac D and Lambert O
Structure of artificial and natural VE-cadherin-based adherens junctions.
Biochemical Society Transactions (2008) 36(Pt 2) : 189-193
Zapun A, Contreras-Martel C and Vernet T
Penicillin-binding proteins and beta-lactam resistance.
FEMS Microbiology Reviews (2008) 32(2) : 361-385
Zapun A, Vernet T and Pinho MG
The different shapes of cocci.
FEMS Microbiology Reviews (2008) 32(2) : 345-360
Publications 2007
Hewat EA, Durmort C, Jacquamet L, Concord E and Gulino-Debrac D
Architecture of the VE-cadherin Hexamer.
Journal of Molecular Biology (2007) 365(3) : 744-751
Royant A, Carpentier P, Ohana J, McGeehan J, Paetzold B, Noirclerc-Savoye M, Verne ?de X, Adam V and Bourgeois D
Advances in spectroscopic methods for biological crystals. 1. Fluorescence lifetime measurements.
Journal of Applied Crystallography (2007) 40(6) : 1105-1112
Publications 2006
Carapito R, Chesnel L, Vernet T and Zapun A
Pneumococcal beta-lactam resistance due to a conformational change in penicillin-binding protein 2x
Journal of Biological Chemistry (2006) 281(3) : 1771-1777
Carapito R, Gallet B, Zapun A and Vernet T
Automated high-throughput process for site-directed mutagenesis, production, purification, and kinetic characterization of enzymes.
Analytical Biochemistry (2006) 355(1) : 110-116
Contreras-Martel C, Job V, Di Guilmi AM, Vernet T, Dideberg O and Dessen A
Crystal structure of penicillin-binding protein 1a (PBP1a) reveals a mutational hotspot implicated in beta-lactam resistance in Streptococcus pneumoniae
Journal of Molecular Biology (2006) 355(4) : 684-696
Faudry E, Santana JM, Ebel C, Vernet T and Teixeira AR
Salivary apyrases of Triatoma infestans are assembled into homo-oligomers.
Biochemical Journal (2006) 396(3) : 509-515
Offant J, Michoux F, Dermiaux A, Biton J and Bourne Y{{}}
Functional characterization of the glycosyltransferase domain of penicillin-binding protein 1a from Thermotoga maritima.
Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics (2006) 1764(6) : 1036-1042
Publications 2005
Chesnel L, Carapito R, Croize J, Dideberg O, Vernet T and Zapun A
Identical Penicillin-Binding Domains in Penicillin-Binding Proteins of Streptococcus pneumoniae Clinical Isolates with Different Levels of beta-Lactam Resistance
Antimicrobial Agents Chemotherapy (2005) 49(7) : 2895-2902
Garau G, Lemaire D, Vernet T, Dideberg O and Di Guilmi AM
Crystal structure of phosphorylcholine esterase domain of the virulence factor choline binding protein E from Streptococcus pneumoniae : New structural features among the metallo-beta -lactamase superfamily.
Journal of Biological Chemistry (2005) 280(31) : 28591-28600
Garau G, Di Guilmi AM and Hall BG
Structure-Based Phylogeny of the Metallo-beta-Lactamases
Antimicrobial Agents Chemotherapy (2005) 49(7) : 2778-2784
Lambeng N, Wallez Y, Rampon C, Cand F, Christe G, Gulino-Debrac D, Vilgrain I and Huber P
Vascular endothelial-cadherin tyrosine phosphorylation in angiogenic and quiescent adult tissues
Circulation Research (2005) 96(3) : 384-391
Macheboeuf P, di Guilmi AM, Job V, Vernet T, Dideberg O and Dessen A
Active site restructuring regulates ligand recognition in class A penicillin-binding proteins (PBPs)
Proceedings of the National Academy of Sciences U S A (2005) 102(3) : 577-582
Morlot C, Pernot L, Le Gouellec A, di Guilmi AM, Vernet T, Dideberg O and Dessen A
Crystal structure of a peptidoglycan synthesis regulatory factor (PBP3) from Streptococcus pneumoniae
Journal of Biological Chemistry (2005) 280(16) : 15984-15991
Noirclerc-Savoye M, Le Gouellec A, Morlot C, Dideberg O, Vernet T and Zapun A
In vitro reconstitution of a trimeric complex of DivIB, DivIC and FtsL, and their transient co-localization at the division site in Streptococcus pneumoniae
Molecular Microbiology (2005) 55(2) : 413-424
Pagliero E, Dideberg O, Vernet T and Di Guilmi AM
The PECACE domain : a new family of enzymes with potential peptidoglycan cleavage activity in Gram-positive bacteria
BMC Genomics (2005) 6 : 19
Publications 2004
Al-Kurdi R, Gulino-Debrac D, Martel L, Legrand J-F, Renault A, Hewat E and Venien-Bryan C
A Soluble VE-cadherin fragment forms 2D arrays of dimers upon binding to a lipid monolayer
Journal of Molecular Biology (2004) 337(4) : 881-892
Delanoe Ayari H, Al Kurdi R, Vallade M, Gulino Debrac D and Riveline D
Membrane and acto-myosin tension promote clustering of adhesion proteins
Proceedings of the National Academy of Science U S A (2004) 101(8) : 2229-34
Delanoë-Ayari H, Lenz P, Brevier J, Weidenhaupt M, Vallade M, Gulino D, Joanny J and Riveline D
Periodic adhesive fingers between contacting cells.
Physical Review Letters (2004) 93(10) : 108102
Fanchon E, Corblin F, Trilling L, Hermant B and Gulino Debrac D
Modeling the molecular network controlling adhesion between endothelial cells : inference and simulation using Constraint Logic Programming in Computational Methods in Systems Biology, édité par Danos V and Schachter V. Lecture Notes in Bioinformatics (2004) 3082 pp 104-118
Faudry E, Lozzi S, Santana J, D’souza-Ault M, Kieffer S, Felix C, Ricart C, Sousa M, Vernet T and Teixeira A
Triatoma infestans apyrases belong to the 5’-nucleotidase family.
Journal of Biological Chemistry (2004) 279(19) : 19607 - 19613
Faudry E, Rocha P S, Vernet T, Lozzi S P and Teixeira a R L
Kinetics of expression of the salivary apyrases in Triatoma infestans
Insect Biochemistry and Molecular Biology (2004) 34(10) : 1051-1058
Morlot C, Noirclerc Savoye M, Zapun A, Dideberg O and Vernet T
The D,D-carboxypeptidase PBP3 organizes the division process of Streptococcus pneumoniae
Molecular Microbiology (2004) 51(6) : 1641-8
Pagliero E, Chesnel L, Hopkins J, Croize J, Dideberg O, Vernet T and di Guilmi A M
Biochemical characterization of streptococcus pneumoniae penicillin-binding protein 2b and its implication in beta-lactam resistance
Antimicrobial Agents and Chemotherapy (2004) 48 : 1848-1855
Pernot L, Chesnel L, Legouellec A, Croize J, Vernet T, Dideberg O and Dessen A
A PBPx from a clinical isolate of spectrococcus pneumoniae exhibits an alternative mechanism for reduction of susceptibility to beta-lactam antibiotics
Journal of Biological Chemistry (2004) 279 : 16463-16470
Publications 2003
Chesnel L, Pernot L, Lemaire D, Champelovier D, Croize J, Dideberg O, Vernet T and Zapun A
The structural modifications induced by the M339F substitution in PBP2x from Streptococcus pneumoniae further decreases the susceptibility to beta-lactams of resistant strains
Journal of Biological Chemistry (2003) 278(45) : 44448-44456
Di Guilmi A M, Dessen A, Dideberg O and Vernet T
Functional characterization of penicillin-binding protein 1b from Streptococcus pneumoniae
Journal of Bacteriology (2003) 185(5) : 1650-8.
Di Guilmi A M, Dessen A, Dideberg O and Vernet T
The glycosyltransferase domain of penicillin-binding protein 2a from Streptococcus pneumoniae catalyzes the polymerization of murein glycan chains
Journal Of Bacteriology (2003) 185(15) : 4418-4423
Hermant B, Bibert S, Concord E, Dublet B, Weidenhaupt M, Vernet T and Gulino Debrac D
Identification of proteases involved in the proteolysis of vascular endothelium cadherin during neutrophil transmigration
Journal of Biological Chemistry (2003) 278(16) : 14002-14012
Hugo N, Weidenhaupt M, Beukes M, Xu B, Janson J C, Vernet T and Altschuh D
VL position 34 is a key determinant for the engineering of stable antibodies with fast dissociation rates
Protein Engineering (2003) 16(5) : 381-386
Job V, Di Guilmi A M, Martin L, Vernet T, Dideberg O and Dessen A
Structural studies of the transpeptidase domain of PBP1a from Streptococcus pneumoniae
Acta Crystallographica. Section D, Biological Crystallography (2003) 59(6) : 1067-1069
Morlot C, Zapun A, Dideberg O and Vernet T
Growth and division of Streptococcus pneumoniae : localization of the high molecular weight penicillin-binding proteins during the cell cycle
Molecular Microbiology (2003) 50(3) : 845-855
Nanao M, Ricard-Blum S, Di Guilmi A M, LeMaire D, Lascoux D, Chabert J, Attree I and Dessen A
Type III secretion proteins PcrV and PcrG from Pseudomonas aeruginosa form a 1:1 complex through high affinity interactions
BMC Microbiology (2003) 3 : 21
Noirclerc-Savoye M, Morlot C, Gerard P, Vernet T and Zapun A
Expression and purification of FtsW and RodA from Streptococcus pneumoniae, two membrane proteins involved in cell division and cell growth, respectively
Protein Expression and Purification (2003) 30(1) : 18-25
Schoehn G, Di Guilmi A M, Lemaire D, Attree I, Weissenhorn W and Dessen A
Oligomerization of type III secretion proteins PopB and PopD precedes pore
Embo Journal (2003) 22(19) : 4957-4967
Timmins J, Schoehn G, Kohlhaas C, Klenk H-D, Ruigrok R W H and Weissenhorn W
Oligomerization and polymerization of the filovirus matrix protein VP40
Virology (2003) 312(2) : 359-368
Timmins J, Schoehn G, Ricard Blum S, Scianimanico S, Vernet T, Ruigrok R W and Weissenhorn W
Ebola virus matrix protein VP40 interaction with human cellular factors Tsg101 and Nedd4
Journal of Molecular Biology (2003) 326(2) : 493-502
Publications 2002
Bibert S, Jaquinod M, Concord E, Ebel C, Hewat E, Vanbelle C, Legrand P, Weidenhaupt M, Vernet T and Gulino-Debrac D
Synergy between extracellular modules of VE cadherin promotes homotypic hexameric interactions
Journal of Biological Chemistry(2002) 277(15) : 12790-12801
Chesnel L, Zapun A, Mouz N, Dideberg O and Vernet T
Increase of the deacylation rate of PBP2x from Streptococcus pneumoniae by single point mutations mimicking the class A beta-lactamases
European Journal of Biochemistry (2002) 269(6) : 1678-83
Choulier L, Orfanoudakis G, Robinson P, Laune D, Ben Khalifa M, Granier C, Weiss E and Altschuh D
Comparative properties of two peptide-antibody interactions as deduced from epitope delineation
Journal of Immunological Methods (2002) 259(1-2) : 77-86
Di Guilmi AM, Dessen A, Dideberg O and Vernet T
Bifunctional penicillin-binding proteins : focus on the glycosyltransferase domain and its specific inhibitor moenomycin
Current Pharmacology Biotechnology (2002) 3(2) : 63-75
Di Guilmi A M and Dessen A
New approaches towards the identification of antibiotic and vaccine targets in Streptococcus pneumoniae.
EMBO Reports (2002) 3(8) : 728-34.
Gerard P, Vernet T and Zapun A
Membrane topology of the Streptococcus pneumoniae FtsW division protein
Journal of Bacteriology (2002) 184(7) : 1925-1931
Grenard P, Bresson-Hadni S, El Alaoui S, Chevallier M, Vuitton DA and Ricard-Blum S
Transglutaminase-mediated cross-linking is involved in the stabilization of extracellular matrix in human liver fibrosis
Journal of Hepatology (2001) 35(3) : 367-75.
Gu Z, Weidenhaupt M, Bingze X, Inanova N, Pavlov M, Zhi-Guo S and Jan-Christer J
Chromatographic methods for the isolation and refolding of proteins from Echerishia coli inclusion bodies
Protein Expression and Purification (2002) 25(1) : 174-179
Ricard-Blum S, Bernocco S, Font B, Moali C, Eichenberger D, Farjanel J, Burchardt E R, Van Der Rest M, Kessler E and Hulmes D J
Interaction Properties of the Procollagen C-proteinase Enhancer Protein Shed Light on the Mechanism of Stimulation of BMP-1.
Journal of Biological Chemistry (2002) 277(37) : 33864-33869.
Weidenhaupt M, Khalifa MB, Hugo N, Choulier L, Altschuh D and Vernet T
Functional mapping of conserved, surface-exposed charges of antibody variable domains
Journal of Molecular Recognition (2002) 15(2) : 94-103.
Publications 2001
Gordon E, Mouz N, Vernet T and Dideberg O
Structural insights into antibiotic-target interactions
In Antibiotic development and resistance edited by Hughes D and Anderson D, Taylor & Francis (2001) : 181-195
Grenard P, Bresson-Hadni S, El Alaoui S, Chevallier M, Vuitton DA and Ricard-Blum S
Transglutaminase-mediated cross-linking is involved in the stabilization of extracellular matrix in human liver fibrosis
Journal of Hepatology (2001) 35(3) : 367-75.
Khalifa MB, Choulier L, Lortat-Jacob H, Altschuh D and Vernet T
BIACORE Data Processing : An Evaluation of the Global Fitting Procedure
Analytical Biochemistry (2001) 293(2) : 194-203
Legrand P, Bibert S, Jaquinod M, Ebel C, Hewat E, Vincent F, Vanbelle C, Concord E, Vernet T and Gulino D
Self-assembly of the Vascular Endothelial Cadherin Ectodomain in a Ca2+- dependent Hexameric Structure
Journal of Biological Chemistry (2001) 276(5) : 3581-3588
Lima AP, dos Reis FC, Serveau C, Lalmanach G, Juliano L, Menard R, Vernet T, Thomas DY, Storer AC and Scharfstein J
Cysteine protease isoforms from Trypanosoma cruzi, cruzipain 2 and cruzain, present different substrate preference and susceptibility to inhibitors
Molecular and Biochemical Parasitology (2001) 114(1) : 41-52
Publications 2000
Di Guilmi, A. M., Mouz, N., Petillot, Y., Forest, E., Dideberg, O. and Vernet, T.
Deacylation Kinetics Analysis of Streptococcus pneumoniae Penicillin- Binding Protein 2x Mutants Resistant to beta-Lactam Antibiotics Using Electrospray Ionization- Mass Spectrometry.
Analytical Biochemistry (2000) 284(2):240-246
Gordon, E., Mouz, N., Vernet, T and Dideberg, O
Structural insights into antibiotic-target interactions
Harwood academic publishers, the Netherlands (2000).
Khalifa, M. B., Weidenhaupt, M., Choulier, L., Chatellier, J., Rauffer-Bruyere, N., Altschuh, D. and Vernet, T.
Effects on interaction kinetics of mutations at the VH-VL interface of Fabs depend on the structural context.
Journal of Molecular Recognition (2000) 13(3):127-139
Michel, G., Flament, D., Barbeyron, T., Vernet, T., Kloareg, B. and Dideberg, O.
Expression, purification, crystallization and preliminary X-ray analysis of the iota-carrageenase from Alteromonas fortis.
Acta Crystallographica D Biological Crystallography (2000) 56(6) : 766-768
Ricard-Blum, S., Dublet, B. and van der Rest, M
Unconventional Collagens : Types VI,VII,VIII,IX,X,XII,XIV,XVI and XIX (2000).
Zapun, A., Grammatyka, S., Deral, G. and Vernet, T.
Calcium-dependent conformational stability of modules 1 and 2 of human gelsolin.
Biochemical Journal (2000) 350(Pt 3):873-881